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The emergent abilities of large language models (LLMs) have demonstrated great potential in solving medical questions. They can possess considerable medical knowledge, but may still hallucinate and are inflexible in the knowledge updates.…

Computation and Language · Computer Science 2024-10-14 Guangzhi Xiong , Qiao Jin , Xiao Wang , Minjia Zhang , Zhiyong Lu , Aidong Zhang

Electronic health records (EHRs) are long, noisy, and often redundant, posing a major challenge for the clinicians who must navigate them. Large language models (LLMs) offer a promising solution for extracting and reasoning over this…

Computation and Language · Computer Science 2025-08-21 Skatje Myers , Dmitriy Dligach , Timothy A. Miller , Samantha Barr , Yanjun Gao , Matthew Churpek , Anoop Mayampurath , Majid Afshar

Medical question answering requires extensive access to specialized conceptual knowledge. The current paradigm, Retrieval-Augmented Generation (RAG), acquires expertise medical knowledge through large-scale corpus retrieval and uses this…

Computation and Language · Computer Science 2025-02-20 Sichu Liang , Linhai Zhang , Hongyu Zhu , Wenwen Wang , Yulan He , Deyu Zhou

Large Language Models (LLMs) have demonstrated significant potential in medical Question Answering (QA), yet they remain prone to hallucinations and ungrounded reasoning, limiting their reliability in high-stakes clinical scenarios. While…

Information Retrieval · Computer Science 2026-01-09 Jessica Ryan , Alexander I. Gumilang , Robert Wiliam , Derwin Suhartono

This paper presents an experience report on the development of Retrieval Augmented Generation (RAG) systems using PDF documents as the primary data source. The RAG architecture combines generative capabilities of Large Language Models…

Software Engineering · Computer Science 2024-10-22 Ayman Asad Khan , Md Toufique Hasan , Kai Kristian Kemell , Jussi Rasku , Pekka Abrahamsson

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta

Large Language Models (LLMs), although powerful in general domains, often perform poorly on domain-specific tasks such as medical question answering (QA). In addition, LLMs tend to function as "black-boxes", making it challenging to modify…

Computation and Language · Computer Science 2024-08-19 Yucheng Shi , Shaochen Xu , Tianze Yang , Zhengliang Liu , Tianming Liu , Quanzheng Li , Xiang Li , Ninghao Liu

This paper presents the development and evaluation of a Retrieval-Augmented Generation (RAG) system for querying the United Kingdom's National Institute for Health and Care Excellence (NICE) clinical guidelines using Large Language Models…

Retrieval Augmented Generation (RAG) is a technique used to augment Large Language Models (LLMs) with contextually relevant, time-critical, or domain-specific information without altering the underlying model parameters. However,…

Information Retrieval · Computer Science 2024-08-20 Laurent Mombaerts , Terry Ding , Adi Banerjee , Florian Felice , Jonathan Taws , Tarik Borogovac

Retrieving and extracting knowledge from extensive research documents and large databases presents significant challenges for researchers, students, and professionals in today's information-rich era. Existing retrieval systems, which rely…

Information Retrieval · Computer Science 2025-02-06 Mohammed-Khalil Ghali , Abdelrahman Farrag , Daehan Won , Yu Jin

Patient-trial matching requires reasoning over long, heterogeneous electronic health records (EHRs) and complex eligibility criteria, posing significant challenges for scalability, generalization, and computational efficiency. Existing…

Computation and Language · Computer Science 2026-04-27 Xiaodi Li , Yang Xiao , Munhwan Lee , Konstantinos Leventakos , Young J. Juhn , David Jones , Terence T. Sio , Wei Liu , Maria Vassilaki , Nansu Zong

Recently, Large Language Model (LLM)-empowered recommender systems have revolutionized personalized recommendation frameworks and attracted extensive attention. Despite the remarkable success, existing LLM-empowered RecSys have been…

Information Retrieval · Computer Science 2025-04-04 Liangbo Ning , Wenqi Fan , Qing Li

LLMs hold great promise for healthcare applications, but the rapid evolution of medical knowledge and errors in training data often cause them to generate outdated or inaccurate information, limiting their applicability in high-stakes…

Computation and Language · Computer Science 2025-11-04 Shujun Xia , Haokun Lin , Yichen Wu , Yinan Zhou , Zixuan Li , Zhongwei Wan , Xingrun Xing , Yefeng Zheng , Xiang Li , Caifeng Shan , Zhenan Sun , Quanzheng Li

Artificial Intelligence (AI) has demonstrated significant potential in healthcare, particularly in disease diagnosis and treatment planning. Recent progress in Medical Large Vision-Language Models (Med-LVLMs) has opened up new possibilities…

Machine Learning · Computer Science 2025-03-04 Peng Xia , Kangyu Zhu , Haoran Li , Tianze Wang , Weijia Shi , Sheng Wang , Linjun Zhang , James Zou , Huaxiu Yao

Timely and accurate identification of student misconceptions is key to improving learning outcomes and pre-empting the compounding of student errors. However, this task is highly dependent on the effort and intuition of the teacher. In this…

Computation and Language · Computer Science 2026-02-03 Joshua Mitton , Prarthana Bhattacharyya , Digory Smith , Thomas Christie , Ralph Abboud , Simon Woodhead

Retrieval-augmented generation (RAG) introduces additional information to enhance large language models (LLMs). In machine translation (MT), previous work typically retrieves in-context examples from paired MT corpora, or domain-specific…

Computation and Language · Computer Science 2025-09-01 Jiaan Wang , Fandong Meng , Yingxue Zhang , Jie Zhou

With the rise of LLMs, there is an increasing need for intelligent recommendation assistants that can handle complex queries and provide personalized, reasoning-driven recommendations. LLM-based recommenders show potential but face…

Information Retrieval · Computer Science 2026-04-10 Jiani Huang , Shijie Wang , Liangbo Ning , Wenqi Fan , Qing Li

The rapid advancement of large-scale language models (LLMs) has shown their potential to transform intelligent education systems (IESs) through automated teaching and learning support applications. However, current IESs often rely on…

Computers and Society · Computer Science 2026-01-09 Yuxin Liu , Zeqing Song , Jiong Lou , Chentao Wu , Jie Li

Large Language Models (LLMs) have demonstrated impressive capabilities across natural language processing tasks. However, their application to specialized domains such as medicine and biology requires further optimization to ensure factual…

Computation and Language · Computer Science 2025-02-06 Seonok Kim

The recent emergence of Medical Large Vision Language Models (Med-LVLMs) has enhanced medical diagnosis. However, current Med-LVLMs frequently encounter factual issues, often generating responses that do not align with established medical…

Machine Learning · Computer Science 2024-10-18 Peng Xia , Kangyu Zhu , Haoran Li , Hongtu Zhu , Yun Li , Gang Li , Linjun Zhang , Huaxiu Yao