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Accurate yet transferable machine-learning interatomic potentials (MLIPs) are essential for accelerating materials and chemical discovery. However, most universal MLIPs overfit to narrow datasets or computational protocols, limiting their…

Machine learning interatomic potentials (MLIPs) enable efficient modeling of molecular interactions with quantum mechanical (QM) accuracy. However, constructing robust and representative training datasets that capture subtle,…

Chemical Physics · Physics 2026-01-28 Lejia Zeng , Xintong Zhang , Yuchan Pei , Lifeng Zhao , Lan Hua , Jincai Yang , Niu Huang

Active learning aims to reduce annotation cost by predicting which samples are useful for a human expert to label. Although this field is quite old, several important challenges to using active learning in real-world settings still remain…

Machine Learning · Computer Science 2021-04-27 Louis Desreumaux , Vincent Lemaire

Active learning (AL) has emerged as a crucial strategy for reducing the prohibitive costs associated with medical image segmentation. However, standard uncertainty-based AL methods typically focus on maximizing performance metrics, ignoring…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Ghazal Danaee , Mélanie Gaillochet , Christian Desrosiers , Herve Lombaert , Sylvain Bouix

Machine learning interatomic potentials (MLIPs) are routinely used atomic simulations, but generating databases of atomic configurations used in fitting these models is a laborious process, requiring significant computational and human…

Materials Science · Physics 2022-07-26 Connor Allen , Albert P. Bartók

We propose a novel approach for constructing training databases for Machine-Learned Interatomic Potential (MLIP) models, specifically designed to capture phase properties across a wide range of conditions. The framework is uniquely…

Materials Science · Physics 2025-12-03 Vincent G. Fletcher , Albert P. Bartók , Livia B. Pártay

The past few years have seen the development of ``universal'' machine-learning interatomic potentials (uMLIPs) capable of approximating the ground-state potential energy surface across a wide range of chemical structures and compositions…

Chemical Physics · Physics 2026-04-20 Sofiia Chorna , Davide Tisi , Cesare Malosso , Wei Bin How , Michele Ceriotti , Sanggyu Chong

Machine-learning interatomic potentials (MLIPs) have become a mainstay in computationally-guided materials science, surpassing traditional force fields due to their flexible functional form and superior accuracy in reproducing physical…

Chemical Physics · Physics 2026-01-13 Igor Vorotnikov , Fedor Romashov , Nikita Rybin , Maxim Rakhuba , Ivan S. Novikov

Many active learning and search approaches are intractable for large-scale industrial settings with billions of unlabeled examples. Existing approaches search globally for the optimal examples to label, scaling linearly or even…

Active Learning (AL) is a human-in-the-loop framework to interactively and adaptively label data instances, thereby enabling significant gains in model performance compared to random sampling. AL approaches function by selecting the hardest…

Machine Learning · Computer Science 2023-06-05 Nathan Beck , Krishnateja Killamsetty , Suraj Kothawade , Rishabh Iyer

Vulnerability detection is crucial for identifying security weaknesses in software systems. However, training effective machine learning models for this task is often constrained by the high cost and expertise required for data annotation.…

Cryptography and Security · Computer Science 2025-08-19 Xiang Lan , Tim Menzies , Bowen Xu

Foundational machine learning interatomic potentials (MLIPs) are being developed at a rapid pace, promising closer and closer approximation to ab initio accuracy. This unlocks the possibility to simulate much larger length and time scales.…

Materials Science · Physics 2026-05-27 Luuk H. E. Kempen , Raffaele Cheula , Mie Andersen

Conventional active learning (AL) frameworks aim to reduce the cost of data annotation by actively requesting the labeling for the most informative data points. However, introducing AL to data hungry deep learning algorithms has been a…

Computer Vision and Pattern Recognition · Computer Science 2022-10-13 Salman Mohamadi , Gianfranco Doretto , Donald A. Adjeroh

Transition metal chromophores with earth-abundant transition metals are an important design target for their applications in lighting and non-toxic bioimaging, but their design is challenged by the scarcity of complexes that simultaneously…

Chemical Physics · Physics 2022-09-16 Chenru Duan , Aditya Nandy , Gianmarco Terrones , David W. Kastner , Heather J. Kulik

Machine learning interatomic potentials (MLIPs) trained on large, chemically diverse datasets are revolutionizing computational chemistry, enabling molecular dynamics simulations of battery electrolytes with near-DFT accuracy over 10,000…

Dopants can tune the performance of MoS2 in various applications, but use of molecular dynamics simulations for doped MoS2 materials discovery is limited by the lack of multi-dopant interatomic potentials. Universal machine learning…

Materials Science · Physics 2026-03-02 Abrar Faiyad , Ashlie Martini

Allegro is a machine learning interatomic potential (MLIP) model designed to predict atomic properties in molecules using E(3) equivariant neural networks. When training this model, there tends to be a trade-off between accuracy and…

Active learning has been increasingly applied to screening functional materials from existing materials databases with desired properties. However, the number of known materials deposited in the popular materials databases such as ICSD and…

Active learning, a powerful paradigm in machine learning, aims at reducing labeling costs by selecting the most informative samples from an unlabeled dataset. However, the traditional active learning process often demands extensive…

Machine Learning · Computer Science 2024-01-17 Gábor Németh , Tamás Matuszka

Active learning promises to provide an optimal training sample selection procedure in the construction of machine learning models. It often relies on minimizing the model's variance, which is assumed to decrease the prediction error. Still,…

Chemical Physics · Physics 2025-11-26 Vivin Vinod , Peter Zaspel