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Background and Objectives: Cardiovascular magnetic resonance (CMR) imaging is a powerful modality in functional and anatomical assessment for various cardiovascular diseases. Sufficient image quality is essential to achieve proper diagnosis…

Image and Video Processing · Electrical Eng. & Systems 2023-10-02 Shahabedin Nabavi , Hossein Simchi , Mohsen Ebrahimi Moghaddam , Ahmad Ali Abin , Alejandro F. Frangi

The work proposes a novel deep-learning framework for the synthesis of three-dimensional MRI volumes from corresponding 3D ultrasound images of the brain, leveraging a modified iteration of the Pix2Pix Generative Adversarial Network (GAN)…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Shubham Singh , Mrunal Bewoor , Ammar Ranapurwala , Satyam Rai , Sheetal Patil

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

Supervised deep learning methods typically rely on large datasets for training. Ethical and practical considerations usually make it difficult to access large amounts of healthcare data, such as medical images, with known task-specific…

Medical Physics · Physics 2023-05-26 Marta Varela , Anil A Bharath

The reconstruction of cortical surfaces from brain magnetic resonance imaging (MRI) scans is essential for quantitative analyses of cortical thickness and sulcal morphology. Although traditional and deep learning-based algorithmic pipelines…

Computer Vision and Pattern Recognition · Computer Science 2022-03-21 Fabian Bongratz , Anne-Marie Rickmann , Sebastian Pölsterl , Christian Wachinger

Nuclear magnetic resonance spectroscopy (MRS) allows for the determination of atomic structures and concentrations of different chemicals in a biochemical sample of interest. MRS is used in vivo clinically to aid in the diagnosis of several…

Medical Physics · Physics 2021-05-04 Zohaib Iqbal , Dan Nguyen , M. Albert Thomas , Steve Jiang

Recent studies on T1-assisted MRI reconstruction for under-sampled images of other modalities have demonstrated the potential of further accelerating MRI acquisition of other modalities. Most of the state-of-the-art approaches have achieved…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Junwei Yang , Xiao-Xin Li , Feihong Liu , Dong Nie , Pietro Lio , Haikun Qi , Dinggang Shen

Recent advances in types and extent of medical imaging technologies has led to proliferation of multimodal quantitative imaging data in cancer. Quantitative medical imaging data refer to numerical representations derived from medical…

This dissertation is devoted to provide advanced nonconvex nonsmooth variational models of (Magnetic Resonance Image) MRI reconstruction, efficient learnable image reconstruction algorithms and parameter training algorithms that improve the…

Optimization and Control · Mathematics 2023-03-06 Wanyu Bian

Longitudinal biomedical studies play a vital role in tracking disease progression, treatment response, and the emergence of resistance mechanisms, particularly in complex disorders such as cancer and neurodegenerative diseases. However, the…

Quantitative Methods · Quantitative Biology 2025-04-28 Maria Demidik , Filippo Utro , Alexey Galda , Karl Jansen , Daniel Blankenberg , Laxmi Parida

Fetal brain MRI is useful for diagnosing brain abnormalities but is challenged by fetal motion. The current protocol for T2-weighted fetal brain MRI is not robust to motion so image volumes are degraded by inter- and intra- slice motion…

Image and Video Processing · Electrical Eng. & Systems 2020-06-24 Junshen Xu , Sayeri Lala , Borjan Gagoski , Esra Abaci Turk , P. Ellen Grant , Polina Golland , Elfar Adalsteinsson

The study of neurodegenerative diseases relies on the reconstruction and analysis of the brain cortex from magnetic resonance imaging (MRI). Traditional frameworks for this task like FreeSurfer demand lengthy runtimes, while its accelerated…

Image and Video Processing · Electrical Eng. & Systems 2020-10-23 Rodrigo Santa Cruz , Leo Lebrat , Pierrick Bourgeat , Clinton Fookes , Jurgen Fripp , Olivier Salvado

Deep learning models have had a great success in disease classifications using large data pools of skin cancer images or lung X-rays. However, data scarcity has been the roadblock of applying deep learning models directly on prostate…

Computer Vision and Pattern Recognition · Computer Science 2021-01-27 Weiwei Zong , Joon Lee , Chang Liu , Eric Carver , Aharon Feldman , Branislava Janic , Mohamed Elshaikh , Milan Pantelic , David Hearshen , Indrin Chetty , Benjamin Movsas , Ning Wen

Deep learning has proven to be a suitable alternative to least-squares (LSQ) fitting for parameter estimation in various quantitative MRI (QMRI) models. However, current deep learning implementations are not robust to changes in MR…

Novel methods for quantitative, transient-state multiparametric imaging are increasingly being demonstrated for assessment of disease and treatment efficacy. Here, we build on these by assessing the most common Non-Cartesian readout…

Learning a robust Variational Autoencoder (VAE) is a fundamental step for many deep learning applications in medical image analysis, such as MRI synthesizes. Existing brain VAEs predominantly focus on single-modality data (i.e., T1-weighted…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Mingjie Li , Edward Kim , Yue Zhao , Ehsan Adeli , Kilian M. Pohl

Magnetic Resonance Imaging (MRI) is a noninvasive imaging technique that provides exquisite soft-tissue contrast without using ionizing radiation. The clinical application of MRI may be limited by long data acquisition times; therefore, MR…

Image and Video Processing · Electrical Eng. & Systems 2020-07-10 Shen Zhao , Lee C. Potter , Kiryung Lee , Rizwan Ahmad

Cortical thickness measurements from magnetic resonance imaging, an important biomarker in many neurodegenerative and neurological disorders, are derived by many tools from an initial voxel-wise tissue segmentation. White matter (WM)…

Image and Video Processing · Electrical Eng. & Systems 2025-03-27 Vinzenz Uhr , Ivan Diaz , Christian Rummel , Richard McKinley

Purpose: This study demonstrated an MR signal multitask learning method for 3D simultaneous segmentation and relaxometry of human brain tissues. Materials and Methods: A 3D inversion-prepared balanced steady-state free precession sequence…

Medical Physics · Physics 2019-12-02 Peng Cao , Jing Liu , Shuyu Tang , Andrew Leynes , Janine M. Lupo , Duan Xu , Peder E. Z. Larson

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Xinrui Ma , Jian Cheng , Wenxin Fan , Ruoyou Wu , Yongquan Ye , Shanshan Wang