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In Question Answering (QA), Retrieval Augmented Generation (RAG) has revolutionized performance in various domains. However, how to effectively capture multi-document relationships, particularly critical for biomedical tasks, remains an…

Computation and Language · Computer Science 2025-04-03 Lingxiao Guan , Yuanhao Huang , Jie Liu

Medical dialogue generation is an important yet challenging task. Most previous works rely on the attention mechanism and large-scale pretrained language models. However, these methods often fail to acquire pivotal information from the long…

Artificial Intelligence · Computer Science 2022-06-20 Yu Zhao , Yunxin Li , Yuxiang Wu , Baotian Hu , Qingcai Chen , Xiaolong Wang , Yuxin Ding , Min Zhang

Predicting diseases solely from patient-side information, such as demographics and self-reported symptoms, has attracted significant research attention due to its potential to enhance patient awareness, facilitate early healthcare…

Artificial Intelligence · Computer Science 2025-12-10 Yibowen Zhao , Yinan Zhang , Zhixiang Su , Lizhen Cui , Chunyan Miao

Information extraction (IE) in scientific literature has facilitated many down-stream tasks. OpenIE, which does not require any relation schema but identifies a relational phrase to describe the relationship between a subject and an object,…

Computation and Language · Computer Science 2021-08-05 Joseph Kuebler , Lingbo Tong , Meng Jiang

While dense biomedical embeddings achieve strong performance, their black-box nature limits their utility in clinical decision-making. Recent question-based interpretable embeddings represent text as binary answers to natural-language…

Computation and Language · Computer Science 2026-03-04 Yixuan Tang , Zhenghong Lin , Yandong Sun , Wynne Hsu , Mong Li Lee , Anthony K. H. Tung

Knowledge Graph Embeddings (KGE) have become a quite popular class of models specifically devised to deal with ontologies and graph structure data, as they can implicitly encode statistical dependencies between entities and relations in a…

Artificial Intelligence · Computer Science 2023-03-27 Michelangelo Diligenti , Francesco Giannini , Stefano Fioravanti , Caterina Graziani , Moreno Falaschi , Giuseppe Marra

Question answering (QA) has achieved promising progress recently. However, answering a question in real-world scenarios like the medical domain is still challenging, due to the requirement of external knowledge and the insufficient quantity…

Artificial Intelligence · Computer Science 2019-12-10 Sheng Shen , Yaliang Li , Nan Du , Xian Wu , Yusheng Xie , Shen Ge , Tao Yang , Kai Wang , Xingzheng Liang , Wei Fan

Current biomedical question answering (QA) systems often assume that medical knowledge applies uniformly, yet real-world clinical reasoning is inherently conditional: nearly every decision depends on patient-specific factors such as…

Large Language Models (LLMs) and Knowledge Graphs (KGs) offer a promising approach to robust and explainable Question Answering (QA). While LLMs excel at natural language understanding, they suffer from knowledge gaps and hallucinations.…

Machine Learning · Computer Science 2025-04-15 Jasper Linders , Jakub M. Tomczak

Motivation: The biomedical literature contains a wealth of chemical-protein interactions (CPIs). Automatically extracting CPIs described in biomedical literature is essential for drug discovery, precision medicine, as well as basic…

Computation and Language · Computer Science 2020-04-27 Cong Sun , Zhihao Yang , Leilei Su , Lei Wang , Yin Zhang , Hongfei Lin , Jian Wang

Question answering (QA) in the field of healthcare has received much attention due to significant advancements in natural language processing. However, existing healthcare QA datasets primarily focus on medical images, clinical notes, or…

Quantitative Methods · Quantitative Biology 2023-10-12 Jungwoo Oh , Gyubok Lee , Seongsu Bae , Joon-myoung Kwon , Edward Choi

Epistemic AI accelerates biomedical discovery by finding hidden connections in the network of biomedical knowledge. The Epistemic AI web-based software platform embodies the concept of knowledge mapping, an interactive process that relies…

Artificial Intelligence · Computer Science 2022-04-04 Da Chen Emily Koo , Heather Bowling , Kenneth Ashworth , David J. Heeger , Stefano Pacifico

In clinical practice, physicians refrain from making decisions when patient information is insufficient. This behavior, known as abstention, is a critical safety mechanism preventing potentially harmful misdiagnoses. Recent investigations…

Computation and Language · Computer Science 2025-09-30 Xilin Dang , Kexin Chen , Xiaorui Su , Ayush Noori , Iñaki Arango , Lucas Vittor , Xinyi Long , Yuyang Du , Marinka Zitnik , Pheng Ann Heng

We present a novel system that automatically extracts and generates informative and descriptive sentences from the biomedical corpus and facilitates the efficient search for relational knowledge. Unlike previous search engines or…

Computation and Language · Computer Science 2023-10-19 Kerui Zhu , Jie Huang , Kevin Chen-Chuan Chang

We describe challenges and advantages unique to coreference resolution in the biomedical domain, and a sieve-based architecture that leverages domain knowledge for both entity and event coreference resolution. Domain-general coreference…

Computation and Language · Computer Science 2016-09-05 Dane Bell , Gus Hahn-Powell , Marco A. Valenzuela-Escárcega , Mihai Surdeanu

Biomedical knowledge graphs (KGs) are vital for drug discovery and clinical decision support but remain incomplete. Large language models (LLMs) excel at extracting biomedical relations, yet their outputs lack standardization and alignment…

Information Retrieval · Computer Science 2025-12-01 Olawumi Olasunkanmi , Mathew Satusky , Hong Yi , Chris Bizon , Harlin Lee , Stanley Ahalt

As an essential task in information extraction (IE), Event-Event Causal Relation Extraction (ECRE) aims to identify and classify the causal relationships between event mentions in natural language texts. However, existing research on ECRE…

Computation and Language · Computer Science 2024-10-08 Zimu Wang , Lei Xia , Wei Wang , Xinya Du

Electrocardiography (ECG) offers critical cardiovascular insights, such as identifying arrhythmias and myocardial ischemia, but enabling automated systems to answer complex clinical questions directly from ECG signals (ECG-QA) remains a…

Signal Processing · Electrical Eng. & Systems 2025-05-13 Hung Manh Pham , Jialu Tang , Aaqib Saeed , Dong Ma

Because protein-protein interactions (PPIs) are crucial to understand living systems, harvesting these data is essential to probe disease development and discern gene/protein functions and biological processes. Some curated datasets contain…

Biomolecules · Quantitative Biology 2024-03-12 Gilchan Park , Sean McCorkle , Carlos Soto , Ian Blaby , Shinjae Yoo

Knowledge graphs (KGs) have emerged as a powerful framework for representing and integrating complex biomedical information. However, assembling KGs from diverse sources remains a significant challenge in several aspects, including entity…

Machine Learning · Computer Science 2023-10-10 Yijia Xiao , Dylan Steinecke , Alexander Russell Pelletier , Yushi Bai , Peipei Ping , Wei Wang
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