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Large language models (LLMs) are increasingly evident for accurate question answering across various domains. However, rigorous evaluation of their performance on complex question-answering (QA) capabilities is essential before deployment…

Computation and Language · Computer Science 2025-09-03 Reem Abdel-Salam , Mary Adewunmi , Modinat A. Abayomi

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

Medical question answer (QA) assistants respond to lay users' health-related queries by synthesizing information from multiple sources using natural language processing and related techniques. They can serve as vital tools to alleviate…

Computation and Language · Computer Science 2024-10-01 Prakash Chandra Sukhwal , Vaibhav Rajan , Atreyi Kankanhalli

The objective of automated Question Answering (QA) systems is to provide answers to user queries in a time efficient manner. The answers are usually found in either databases (or knowledge bases) or a collection of documents commonly…

Artificial Intelligence · Computer Science 2021-11-12 Krishanu Das Baksi

Large language models (LLMs) show remarkable potential in scientific hypothesis discovery. However, existing approaches face two critical limitations: they treat divergent exploratory ideation and convergent fine-grained refinement as…

Computation and Language · Computer Science 2026-05-29 Hongran An , Zonglin Yang

Biomedical knowledge graphs (KGs) are widely used across research and translational settings, yet their design decisions and implementation are often opaque. Unlike ontologies that more frequently adhere to established creation principles,…

Open Information Extraction (OIE) systems seek to compress the factual propositions of a sentence into a series of n-ary tuples. These tuples are useful for downstream tasks in natural language processing like knowledge base creation,…

Computation and Language · Computer Science 2021-01-28 Jacob Solawetz , Stefan Larson

Electronic health records (EHRs) hold significant value for research and applications. As a new way of information extraction, question answering (QA) can extract more flexible information than conventional methods and is more accessible to…

Computation and Language · Computer Science 2024-02-20 Huaiyuan Ying , Sheng Yu

Biomedical datasets are often modeled as knowledge graphs (KGs) because they capture the multi-relational, heterogeneous, and dynamic natures of biomedical systems. KG completion (KGC), can, therefore, help researchers make predictions to…

Artificial Intelligence · Computer Science 2023-07-18 Lauren Nicole DeLong , Ramon Fernández Mir , Zonglin Ji , Fiona Niamh Coulter Smith , Jacques D. Fleuriot

Currently, there is a rapidly increasing need for high-quality biomedical knowledge graphs (BioKG) that provide direct and precise biomedical knowledge. In the context of COVID-19, this issue is even more necessary to be highlighted.…

Artificial Intelligence · Computer Science 2020-12-03 Sendong Zhao , Bing Qin , Ting Liu , Fei Wang

Medical Visual Question Answering (MedVQA) is a promising field for developing clinical decision support systems, yet progress is often limited by the available datasets, which can lack clinical complexity and visual diversity. To address…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Sushant Gautam , Michael A. Riegler , Pål Halvorsen

Objective: Question answering (QA) systems have the potential to improve the quality of clinical care by providing health professionals with the latest and most relevant evidence. However, QA systems have not been widely adopted. This…

Computation and Language · Computer Science 2024-02-06 Gregory Kell , Angus Roberts , Serge Umansky , Linglong Qian , Davide Ferrari , Frank Soboczenski , Byron Wallace , Nikhil Patel , Iain J Marshall

Despite the excitement behind biomedical artificial intelligence (AI), access to high-quality, diverse, and large-scale data - the foundation for modern AI systems - is still a bottleneck to unlocking its full potential. To address this…

Understanding complex biomolecular mechanisms requires multi-step reasoning across molecular interactions, signaling cascades, and metabolic pathways. While large language models(LLMs) show promise in such tasks, their application to…

Artificial Intelligence · Computer Science 2025-11-12 Tianwen Lyu , Xiang Zhuang , Keyan Ding , Xinzhe Cao , Lei Liang , Wei Zhao , Qiang Zhang , Huajun Chen

Quantum error mitigation (QEM) is essential for the noisy intermediate-scale quantum era, and will remain relevant for early fault-tolerant quantum computers, where logical error rates are still significant. However, most QEM methods incur…

Quantum Physics · Physics 2026-03-25 Pablo Díez-Valle , Gaurav Saxena , Jack S. Baker , Jun-Ho Lee , Thi Ha Kyaw

We introduce PubMedQA, a novel biomedical question answering (QA) dataset collected from PubMed abstracts. The task of PubMedQA is to answer research questions with yes/no/maybe (e.g.: Do preoperative statins reduce atrial fibrillation…

Computation and Language · Computer Science 2019-09-16 Qiao Jin , Bhuwan Dhingra , Zhengping Liu , William W. Cohen , Xinghua Lu

Biomedical evidence synthesis relies on accurate extraction of methodological, laboratory, and outcome variables from full-text research articles, yet these variables are embedded in complex scientific PDFs that make manual abstraction…

Computation and Language · Computer Science 2026-01-22 Pouria Mortezaagha , Joseph Shaw , Bowen Sun , Arya Rahgozar

Here we present a holistic approach for data exploration on dense knowledge graphs as a novel approach with a proof-of-concept in biomedical research. Knowledge graphs are increasingly becoming a vital factor in knowledge mining and…

Artificial Intelligence · Computer Science 2019-12-16 Jens Dörpinghaus , Alexander Apke , Vanessa Lage-Rupprecht , Andreas Stefan

Medical question answering (QA) systems have the potential to answer clinicians uncertainties about treatment and diagnosis on demand, informed by the latest evidence. However, despite the significant progress in general QA made by the NLP…

Computation and Language · Computer Science 2021-09-23 Gregory Kell , Iain J. Marshall , Byron C. Wallace , Andre Jaun

This paper presents a principled and scalable framework for systematically generating complex Question Answering (QA) data. In the core of this framework is a graphlet-anchored generation process, where small subgraphs from a Knowledge…

Computation and Language · Computer Science 2026-04-30 Richard A. A. Jonker , Bárbara Maria Ribeiro de Abreu Martins , Sérgio Matos