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In augmented reality (AR)-guided surgical navigation, preoperative organ models are superimposed onto the patient's intraoperative anatomy to visualize critical structures such as vessels and tumors. Accurate deformation modeling is…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Zheng Han , Jun Zhou , Jialun Pei , Jing Qin , Yingfang Fan , Qi Dou

The bicuspid aortic valve (BAV) is the most prevalent congenital heart defect and may require surgery for complications such as stenosis, regurgitation, and aortopathy. BAV repair surgery is effective but challenging due to the…

Valvular heart disease is prevalent and a major contributor to heart failure. Valve leaflet strain is a promising metric for evaluating the mechanics underlying the initiation and progression of valvular pathology. However, generalizable…

Quantitative Methods · Quantitative Biology 2026-02-25 Wensi Wu , Matthew Daemer , Jeffrey A. Weiss , Alison M. Pouch , Matthew A. Jolley

Image registration is an ill-posed inverse problem which often requires regularisation on the solution space. In contrast to most of the current approaches which impose explicit regularisation terms such as smoothness, in this paper we…

Image and Video Processing · Electrical Eng. & Systems 2020-07-09 Chen Qin , Shuo Wang , Chen Chen , Huaqi Qiu , Wenjia Bai , Daniel Rueckert

An automatic elastic registration method suited for vascularized organs is proposed. The vasculature in both the preoperative and intra-operative images is represented as a graph. A typical application of this method is the fusion of…

Computer Vision and Pattern Recognition · Computer Science 2019-12-16 Jaime Garcia Guevara , Igor Peterlik , Marie-Odile Berger , Stéphane Cotin

In image-guided liver surgery, 3D-3D non-rigid registration methods play a crucial role in estimating the mapping between the preoperative model and the intraoperative surface represented as point clouds, addressing the challenge of tissue…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Zixin Yang , Richard Simon , Kelly Merrell , Cristian. A. Linte

Each year, approximately 300,000 heart valve repair or replacement procedures are performed worldwide, including approximately 70,000 aortic valve replacement surgeries in the United States alone. This paper describes progress in…

Medical image registration is a challenging task involving the estimation of spatial transformations to establish anatomical correspondence between pairs or groups of images. Recently, deep learning-based image registration methods have…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Xiang Chen , Yan Xia , Nishant Ravikumar , Alejandro F Frangi

Deformable image registration is a fundamental problem in the field of medical image analysis. During the last years, we have witnessed the advent of deep learning-based image registration methods which achieve state-of-the-art performance,…

Image and Video Processing · Electrical Eng. & Systems 2020-02-03 Lucas Mansilla , Diego H. Milone , Enzo Ferrante

Deformable medical image registration is an essential task in computer-assisted interventions. This problem is particularly relevant to oncological treatments, where precise image alignment is necessary for tracking tumor growth, assessing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Stefano Fogarollo , Gregor Laimer , Reto Bale , Matthias Harders

A method is presented for the registration of MRA and 4D Flow images, with the goal of calculating blood flow properties using both modalities simultaneously. In particular, the method produces an alignment of segmentations of vessel…

Quantitative Methods · Quantitative Biology 2025-04-28 Dan Lior , Craig G. Rusin , Justin Weigand , Kristina V. Montez , Yimo Wang , Silvana Molossi , Daniel J. Penny , Charles Puelz

Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Pan Du , Delin An , Chaoli Wang , Jian-Xun Wang

Mechanical heart valve replacement is the preferred alternative in younger patients with severe symptomatic aortic valve disease. However, thrombus and pannus formations are common complications associated with bileaflet mechanical heart…

Medical Physics · Physics 2019-11-14 Ahmed Darwish , Giuseppe Di Labbio , Wael Saleh , Othman Smadi , Lyes Kadem

Cardiovascular magnetic resonance (CMR) is the gold standard for assessing cardiac function, but individual cardiac cycles complicate automatic temporal comparison or sub-phase analysis. Accurate cardiac keyframe detection can eliminate…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Sven Koehler , Sarah Kaye Mueller , Jonathan Kiekenap , Gerald Greil , Tarique Hussain , Samir Sarikouch , Florian André , Norbert Frey , Sandy Engelhardt

This paper aims to create a deep learning framework that can estimate the deformation vector field (DVF) for directly registering abdominal MRI-CT images. The proposed method assumed a diffeomorphic deformation. By using topology-preserved…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Yang Lei , Luke A. Matkovic , Justin Roper , Tonghe Wang , Jun Zhou , Beth Ghavidel , Mark McDonald , Pretesh Patel , Xiaofeng Yang

Accurate registration of medical images is vital for doctor's diagnosis and quantitative analysis. In this paper, we propose a new deformable medical image registration method based on average geometric transformations and VoxelMorph CNN…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Yongpei Zhu , Zicong Zhou , Guojun Liao , Kehong Yuan

Medical image registration is a fundamental task in medical image analysis, aiming to establish spatial correspondences between paired images. However, existing unsupervised deformable registration methods rely solely on intensity-based…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Hao Xu , Tengfei Xue , Jianan Fan , Dongnan Liu , Yuqian Chen , Fan Zhang , Carl-Fredrik Westin , Ron Kikinis , Lauren J. O'Donnell , Weidong Cai

This work introduces AD-SVFD, a deep learning model for the deformable registration of vascular shapes to a pre-defined reference and for the generation of synthetic anatomies. AD-SVFD operates by representing each geometry as a weighted…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Riccardo Tenderini , Luca Pegolotti , Fanwei Kong , Stefano Pagani , Francesco Regazzoni , Alison L. Marsden , Simone Deparis

Aortic shape analysis plays a key role in cardiovascular diagnostics, treatment planning, and understanding disease progression. We present a robust, fully automated pipeline for aortic shape analysis from cardiac MRI, combining deep…

Tissues and Organs · Quantitative Biology 2025-09-15 Nairouz Shehata , Amr Elsawy , Mohamed Nagy , Muhammad ElMahdy , Mariam Ali , Soha Romeih , Heba Aguib , Magdi Yacoub , Ben Glocker

Lung injuries, such as ventilator-induced lung injury and radiation-induced lung injury, can lead to heterogeneous alterations in the biomechanical behavior of the lungs. While imaging methods, e.g., X-ray and static computed tomography…

Medical Physics · Physics 2024-07-08 Sunder Neelakantan , Tanmay Mukherjee , Kyle J. Myers , Rahim Rizi , Reza Avazmohammadi
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