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Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

Hardware Architecture · Computer Science 2021-11-04 Damla Senol Cali

The deep feedforward neural networks (DNNs) are increasingly deployed in socioeconomic critical decision support software systems. DNNs are exceptionally good at finding minimal, sufficient statistical patterns within their training data.…

Software Engineering · Computer Science 2023-04-11 Verya Monjezi , Ashutosh Trivedi , Gang Tan , Saeid Tizpaz-Niari

Accurately estimating decision boundaries in black box systems is critical when ensuring safety, quality, and feasibility in real-world applications. However, existing methods iteratively refine boundary estimates by sampling in regions of…

Computational Geometry · Computer Science 2026-02-17 Mithun Goutham , Riccardo DalferroNucci , Stephanie Stockar , Meghna Menon , Sneha Nayak , Harshad Zade , Chetan Patel , Mario Santillo

Dynamic symbolic execution (DSE) is a powerful test generation approach based on an exploration of the path space of the program under test. Well-adapted for path coverage, this approach is however less efficient for conditions, decisions,…

Software Engineering · Computer Science 2022-12-26 Nicolas Berthier , Steven De Oliveira , Nikolai Kosmatov , Delphine Longuet , Romain Soulat

This paper demonstrates the predictive superiority of discrete wavelet transform (DWT) over previously used methods of feature extraction in the diagnosis of epileptic seizures from EEG data. Classification accuracy, specificity, and…

Computational Engineering, Finance, and Science · Computer Science 2021-02-03 Cyrille Feudjio , Victoire Djimna Noyum , Younous Perieukeu Mofendjou , Rockefeller , Ernest Fokoué

The study emphasizes the challenge of finding the optimal trade-off between bias and variance, especially as hyperparameter optimization increases in complexity. Through empirical analysis, three hyperparameter tuning algorithms…

Machine Learning · Computer Science 2024-08-30 Subhasis Dasgupta , Jaydip Sen

A deductive program synthesis tool takes a specification as input and derives a program that satisfies the specification. The drawback of this approach is that search spaces for such correct programs tend to be enormous, making it difficult…

Neural and Evolutionary Computing · Computer Science 2023-01-23 Yutaka Nagashima

Diffusion modeling (DM) has high-quality generative performance, and the sampling problem is an important part of the DM performance. Thanks to efficient differential equation solvers, the sampling speed can be reduced while higher sampling…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Zitong Cheng

Tabular data generation has become increasingly essential for enabling robust machine learning applications, which require large-scale, high-quality data. Existing solutions leverage generative models to learn original data distributions.…

Machine Learning · Computer Science 2025-12-29 Yafeng Tang , Xiaoou Ding , Jianzhuo Du , Zishuo Yan , Zhuang Ma , Zheng Liang , Zekai Qian , Hongzhi Wang

Models obtained by decision tree induction techniques excel in being interpretable.However, they can be prone to overfitting, which results in a low predictive performance. Ensemble techniques are able to achieve a higher accuracy. However,…

Machine Learning · Statistics 2016-11-18 Gilles Vandewiele , Olivier Janssens , Femke Ongenae , Filip De Turck , Sofie Van Hoecke

One common belief is that with complex models and pre-training on large-scale datasets, transformer-based methods for referring expression comprehension (REC) perform much better than existing graph-based methods. We observe that since most…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Jingcheng Ke , Dele Wang , Jun-Cheng Chen , I-Hong Jhuo , Chia-Wen Lin , Yen-Yu Lin

Deep Neural Networks (DNNs) have had a significant impact on domains like autonomous vehicles and smart cities through low-latency inferencing on edge computing devices close to the data source. However, DNN training on the edge is poorly…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-29 Prashanthi S. K. , Sai Anuroop Kesanapalli , Yogesh Simmhan

Speculative decoding (SD) has emerged as an effective technique to accelerate large language model (LLM) inference without compromising output quality. However, the achievable speedup largely depends on the effectiveness of the drafting…

Computation and Language · Computer Science 2025-11-04 Min Fang , Zhihui Fu , Qibin Zhao , Jun Wang

Self-consistency boosts inference-time performance by sampling multiple reasoning traces in parallel and voting. However, in constrained domains like math and code, this strategy is compute-inefficient because it samples with replacement,…

Machine Learning · Computer Science 2026-04-23 Xueyan Li , Johannes Zenn , Ekaterina Fadeeva , Guinan Su , Mrinmaya Sachan , Jonas Geiping

Deep neural network (DNN) models have shown remarkable success in many real-world scenarios, such as object detection and classification. Unfortunately, these models are not yet widely adopted in health monitoring due to exceptionally high…

Machine Learning · Computer Science 2025-03-14 Johnson Loh , Lyubov Dudchenko , Justus Viga , Tobias Gemmeke

The boom of DL technology leads to massive DL models built and shared, which facilitates the acquisition and reuse of DL models. For a given task, we encounter multiple DL models available with the same functionality, which are considered…

Software Engineering · Computer Science 2021-03-10 Linghan Meng , Yanhui Li , Lin Chen , Zhi Wang , Di Wu , Yuming Zhou , Baowen Xu

We propose a probabilistic model for interpreting gene expression levels that are observed through single-cell RNA sequencing. In the model, each cell has a low-dimensional latent representation. Additional latent variables account for…

Machine Learning · Computer Science 2018-01-18 Romain Lopez , Jeffrey Regier , Michael Cole , Michael Jordan , Nir Yosef

High-throughput sequencing (HTS) is revolutionizing biological research by enabling scientists to quickly and cheaply query variation at a genomic scale. Despite the increasing ease of obtaining such data, using these data effectively still…

Genomics · Quantitative Biology 2012-11-09 Sonal Singhal

Possessing the five-year durability rate of nearly 5%, currently, the fourth leading cause for cancer-related deaths is pancreatic cancer. Previously, several works have resolved that early diagnosis performs a meaningful function in…

Genomics · Quantitative Biology 2023-06-22 Azmain Yakin Srizon

Automated test-generation research overwhelmingly assumes the correctness of focal methods, yet practitioners routinely face non-regression scenarios where the focal method may be defective. A baseline evaluation of EVOSUITE and two leading…

Software Engineering · Computer Science 2026-02-03 Pengyu Xue , Yuxiang Zhang , Zhen Yang , Xiaoxue Ren , Xiang Li , Pengfei Hu , Linhao Wu , Kainan Li
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