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Large language models (LLMs) show promise in automating clinical diagnosis, yet their non-transparent decision-making and limited alignment with diagnostic standards hinder trust and clinical adoption. We address this challenge by proposing…

Artificial Intelligence · Computer Science 2025-11-25 Yining Yuan , J. Ben Tamo , Micky C. Nnamdi , Yifei Wang , May D. Wang

This study evaluates the capacity of large language models (LLMs) to generate structured clinical consultation templates for electronic consultation. Using 145 expert-crafted templates developed and routinely used by Stanford's eConsult…

The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

Computation and Language · Computer Science 2023-12-08 Angeela Acharya , Sulabh Shrestha , Anyi Chen , Joseph Conte , Sanja Avramovic , Siddhartha Sikdar , Antonios Anastasopoulos , Sanmay Das

Large language models (LLMs) have become increasingly popular in medical domains to assist physicians with a variety of clinical and operational tasks. Given the fast-paced and high-stakes environment of emergency departments (EDs), small…

Computation and Language · Computer Science 2025-10-07 Zirui Wang , Jiajun Wu , Braden Teitge , Jessalyn Holodinsky , Steve Drew

Clinical practice guidelines (CPGs) provide evidence-based recommendations for patient care; however, integrating them into Artificial Intelligence (AI) remains challenging. Previous approaches, such as rule-based systems, face significant…

Artificial Intelligence · Computer Science 2026-01-08 Ruiqi Deng , Geoffrey Martin , Tony Wang , Gongbo Zhang , Yi Liu , Chunhua Weng , Yanshan Wang , Justin F Rousseau , Yifan Peng

Evaluating the performance and biases of large language models (LLMs) through role-playing scenarios is becoming increasingly common, as LLMs often exhibit biased behaviors in these contexts. Building on this line of research, we introduce…

Computation and Language · Computer Science 2025-06-30 Junho Myung , Yeon Su Park , Sunwoo Kim , Shin Yoo , Alice Oh

Large language models (LLMs) have shown considerable potential in supporting medical diagnosis. However, their effective integration into clinical workflows is hindered by physicians' difficulties in perceiving and trusting LLM…

Human-Computer Interaction · Computer Science 2026-01-28 Yuansong Xu , Yichao Zhu , Haokai Wang , Yuchen Wu , Yang Ouyang , Hanlu Li , Wenzhe Zhou , Xinyu Liu , Chang Jiang , Quan Li

Peer review is fundamental to scientific research, but the growing volume of publications has intensified the challenges of this expertise-intensive process. While LLMs show promise in various scientific tasks, their potential to assist…

Computation and Language · Computer Science 2025-07-04 Zhijian Xu , Yilun Zhao , Manasi Patwardhan , Lovekesh Vig , Arman Cohan

Large Language Models (LLMs) have demonstrated great potential for conducting diagnostic conversations but evaluation has been largely limited to language-only interactions, deviating from the real-world requirements of remote care…

Evaluating large language models (LLMs) for medical applications remains challenging due to benchmark saturation, limited data accessibility, and insufficient coverage of relevant tasks. Existing suites have either saturated, heavily depend…

Objectives: To evaluate the current limitations of large language models (LLMs) in medical question answering, focusing on the quality of datasets used for their evaluation. Materials and Methods: Widely-used benchmark datasets, including…

Computation and Language · Computer Science 2025-07-15 Mahmoud Alwakeel , Aditya Nagori , Vijay Krishnamoorthy , Rishikesan Kamaleswaran

We present MedPI, a high-dimensional benchmark for evaluating large language models (LLMs) in patient-clinician conversations. Unlike single-turn question-answer (QA) benchmarks, MedPI evaluates the medical dialogue across 105 dimensions…

Computation and Language · Computer Science 2026-01-09 Diego Fajardo V. , Oleksii Proniakin , Victoria-Elisabeth Gruber , Razvan Marinescu

Evaluation of large language model (LLM) outputs requires users to make critical judgments about the best outputs across various configurations. This process is costly and takes time given the large amounts of data. LLMs are increasingly…

This study explores the intersection of electroencephalography (EEG) microstates and Large Language Models (LLMs) to enhance the assessment of cognitive load states. By utilizing EEG microstate features, the research aims to fine-tune LLMs…

Human-Computer Interaction · Computer Science 2025-08-12 Bujar Raufi

Introduction: Generative artificial intelligence (AI), particularly large language models (LLMs), holds significant promise for Health Economics and Outcomes Research (HEOR). However, standardized reporting guidance for LLM-assisted…

Computers and Society · Computer Science 2025-06-09 Rachael L. Fleurence , Dalia Dawoud , Jiang Bian , Mitchell K. Higashi , Xiaoyan Wang , Hua Xu , Jagpreet Chhatwal , Turgay Ayer

Large language models (LLMs) are increasingly leveraged as foundational backbones in the development of advanced recommender systems, offering enhanced capabilities through their extensive knowledge and reasoning. Existing llm-based…

Information Retrieval · Computer Science 2025-02-21 Minjie Hong , Yan Xia , Zehan Wang , Jieming Zhu , Ye Wang , Sihang Cai , Xiaoda Yang , Quanyu Dai , Zhenhua Dong , Zhimeng Zhang , Zhou Zhao

The ability of large language models (LLMs) to follow natural language instructions with human-level fluency suggests many opportunities in healthcare to reduce administrative burden and improve quality of care. However, evaluating LLMs on…

Home-based music therapy devices require accessible and cost-effective solutions for users to understand and track their therapeutic progress. Traditional physiological signal analysis, particularly EEG interpretation, relies heavily on…

Human-Computer Interaction · Computer Science 2026-04-27 Huixin Xue , Guangjun Xu , Shihong Ren , Xian Gao , Ruian Tie , Zhen Zhou , Hao Liu , Yue Gao

Physicians considering clinical trials for their patients are met with the laborious process of checking many text based eligibility criteria. Large Language Models (LLMs) have shown to perform well for clinical information extraction and…

Machine Learning · Computer Science 2023-06-30 Danny M. den Hamer , Perry Schoor , Tobias B. Polak , Daniel Kapitan

Recently, the fast development of Large Language Models (LLMs) such as ChatGPT has significantly advanced NLP tasks by enhancing the capabilities of conversational models. However, the application of LLMs in the recommendation domain has…

Information Retrieval · Computer Science 2023-08-24 Junling Liu , Chao Liu , Peilin Zhou , Qichen Ye , Dading Chong , Kang Zhou , Yueqi Xie , Yuwei Cao , Shoujin Wang , Chenyu You , Philip S. Yu