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Artificial Intelligence (AI) is revolutionizing scientific research, yet its growing integration into laboratory environments presents critical safety challenges. Large language models (LLMs) and vision language models (VLMs) now assist in…

Large Language Models (LLMs) have achieved unparalleled success across diverse language modeling tasks in recent years. However, this progress has also intensified ethical concerns, impacting the deployment of LLMs in everyday contexts.…

Objectieve:This review aims to deliver a comprehensive analysis of Large Language Models (LLMs) utilization in mental health care, evaluating their effectiveness, identifying challenges, and exploring their potential for future application.…

Large language models (LLMs) often match or exceed clinician-level performance on medical benchmarks, yet very few are evaluated on real clinical data or examined beyond headline metrics. We present, to our knowledge, the first evaluation…

The safety evaluation of large language models (LLMs) remains largely centered on English, leaving non-English languages and culturally grounded risks underexplored. In this work, we investigate LLM safety in the context of the Thai…

Computation and Language · Computer Science 2026-03-09 Trapoom Ukarapol , Nut Chukamphaeng , Kunat Pipatanakul , Pakhapoom Sarapat

Large language models (LLMs) have offered new opportunities for emotional support, and recent work has shown that they can produce empathic responses to people in distress. However, long-term mental well-being requires emotional…

Computation and Language · Computer Science 2024-08-09 Hongli Zhan , Allen Zheng , Yoon Kyung Lee , Jina Suh , Junyi Jessy Li , Desmond C. Ong

Large Language Models (LLMs) are increasingly deployed as agents that operate in real-world environments, introducing safety risks beyond linguistic harm. Existing agent safety evaluations rely on risk-oriented tasks tailored to specific…

Artificial Intelligence · Computer Science 2026-02-04 Jingnan Zheng , Yanzhen Luo , Jingjun Xu , Bingnan Liu , Yuxin Chen , Chenhang Cui , Gelei Deng , Chaochao Lu , Xiang Wang , An Zhang , Tat-Seng Chua

Large Language Models (LLMs) have emerged as potent tools for advancing the United Nations' Sustainable Development Goals (SDGs). However, the attitudinal disparities between LLMs and humans towards these goals can pose significant…

Computers and Society · Computer Science 2025-01-17 Qingyang Wu , Ying Xu , Tingsong Xiao , Yunze Xiao , Yitong Li , Tianyang Wang , Yichi Zhang , Shanghai Zhong , Yuwei Zhang , Wei Lu , Yifan Yang

The rapid adoption of large language models (LLMs) has spurred extensive research into their encoded moral norms and decision-making processes. Much of this research relies on prompting LLMs with survey-style questions to assess how well…

Artificial Intelligence · Computer Science 2025-01-31 Pratik S. Sachdeva , Tom van Nuenen

Large language models (LLMs) are increasingly consulted by parents for pediatric guidance, yet their safety under real-world adversarial pressures is poorly understood. Anxious parents often use urgent language that can compromise model…

Artificial Intelligence · Computer Science 2025-12-19 Vahideh Zolfaghari

We present an open-source benchmark and evaluation framework for assessing emotional boundary handling in Large Language Models (LLMs). Using a dataset of 1156 prompts across six languages, we evaluated three leading LLMs (GPT-4o,…

Computation and Language · Computer Science 2025-02-24 David Noever , Grant Rosario

The latest large language models (LLMs) such as ChatGPT, exhibit strong capabilities in automated mental health analysis. However, existing relevant studies bear several limitations, including inadequate evaluations, lack of prompting…

Computation and Language · Computer Science 2024-10-03 Kailai Yang , Shaoxiong Ji , Tianlin Zhang , Qianqian Xie , Ziyan Kuang , Sophia Ananiadou

Biased AI-generated medical advice and misdiagnoses can jeopardize patient safety, making the integrity of AI in healthcare more critical than ever. As Large Language Models (LLMs) take on a growing role in medical decision-making,…

Computation and Language · Computer Science 2024-10-10 Pardis Sadat Zahraei , Zahra Shakeri

Large Language Models (LLMs) are increasingly utilized for mental health support; however, current safety benchmarks often fail to detect the complex, longitudinal risks inherent in therapeutic dialogue. We introduce an evaluation framework…

Computation and Language · Computer Science 2026-03-06 Ian Steenstra , Paola Pedrelli , Weiyan Shi , Stacy Marsella , Timothy W. Bickmore

Psychometric tests are increasingly used to assess psychological constructs in large language models (LLMs). However, it remains unclear whether these tests -- originally developed for humans -- yield meaningful results when applied to…

Computation and Language · Computer Science 2026-01-28 Jana Jung , Marlene Lutz , Indira Sen , Markus Strohmaier

Large language models (LLMs) often produce confident but incorrect answers in settings where abstention would be safer. Standard evaluation protocols, however, require a response and do not account for how confidence should guide decisions…

Computation and Language · Computer Science 2026-04-06 Sean Wu , Fredrik K. Gustafsson , Edward Phillips , Boyan Gao , Anshul Thakur , David A. Clifton

As large language models (LLMs) increasingly mediate ethically sensitive decisions, understanding their moral reasoning processes becomes imperative. This study presents a comprehensive empirical evaluation of 14 leading LLMs, both…

Computation and Language · Computer Science 2025-08-12 Junchen Ding , Penghao Jiang , Zihao Xu , Ziqi Ding , Yichen Zhu , Jiaojiao Jiang , Yuekang Li

Large Language Models (LLMs) have emerged as powerful candidates to inform clinical decision-making processes. While these models play an increasingly prominent role in shaping the digital landscape, two growing concerns emerge in…

Computation and Language · Computer Science 2024-04-24 Raphael Poulain , Hamed Fayyaz , Rahmatollah Beheshti

Large Language Models (LLMs) are vulnerable to jailbreak attacks that exploit weaknesses in traditional safety alignment, which often relies on rigid refusal heuristics or representation engineering to block harmful outputs. While they are…

Computation and Language · Computer Science 2025-10-01 Yuyou Zhang , Miao Li , William Han , Yihang Yao , Zhepeng Cen , Ding Zhao

Large language models (LLMs) show significant potential in healthcare, prompting numerous benchmarks to evaluate their capabilities. However, concerns persist regarding the reliability of these benchmarks, which often lack clinical…

Computation and Language · Computer Science 2026-04-30 Wenting Chen , Guo Yu , Yiu-Fai Cheung , Meidan Ding , Jie Liu , Zizhan Ma , Wenxuan Wang , Linlin Shen