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Large Language Models are expressive tools that enable complex tasks of text understanding within Computational Social Science. Their versatility, while beneficial, poses a barrier for establishing standardized best practices within the…

Computers and Society · Computer Science 2024-08-05 Anders Giovanni Møller , Luca Maria Aiello

We describe the accurate prediction of ligand-protein interaction (LPI) affinities, also known as drug-target interactions (DTI), with instruction fine-tuned pretrained generative small language models (SLMs). We achieved accurate…

Machine Learning · Computer Science 2024-07-02 Ben Fauber

Achieving consensus in group decision-making often involves overcoming significant challenges, particularly in reconciling diverse perspectives and mitigating biases that hinder agreement. Traditional methods relying on human facilitators…

Human-Computer Interaction · Computer Science 2025-03-21 Loukas Triantafyllopoulos , Dimitris Kalles

Recent advances in Large Language Models (LLMs) have opened new perspectives for automation in optimization. While several studies have explored how LLMs can generate or solve optimization models, far less is understood about what these…

Artificial Intelligence · Computer Science 2025-12-16 Francesca Da Ros , Luca Di Gaspero , Kevin Roitero

Reinforcement Learning with Verifiable Rewards (RLVR) plays a key role in stimulating the explicit reasoning capability of Large Language Models (LLMs). We can achieve expert-level performance in some specific domains via RLVR, such as…

Artificial Intelligence · Computer Science 2026-03-12 Haoqing Wang , Xiang Long , Ziheng Li , Yilong Xu , Tingguang Li , Yehui Tang

In our study, we evaluated large language model (LLM) performance on pharmacy licensure-style question-answering tasks and developed an external knowledge integration method to improve accuracy. We benchmarked ten LLMs with varying…

With the advent of the information explosion era, the importance of recommendation systems in various applications is increasingly significant. Traditional collaborative filtering algorithms are widely used due to their effectiveness in…

Artificial Intelligence · Computer Science 2024-12-30 Xueting Lin , Zhan Cheng , Longfei Yun , Qingyi Lu , Yuanshuai Luo

Acute poly-substance intoxication requires rapid, life-saving decisions under substantial uncertainty, as clinicians must rely on incomplete ingestion details and nonspecific symptoms. Effective diagnostic reasoning in this chaotic…

Computation and Language · Computer Science 2026-04-01 Nico Oberländer , David Bani-Harouni , Tobias Zellner , Nassir Navab , Florian Eyer , Matthias Keicher

Evaluating open-ended written examination responses from students is an essential yet time-intensive task for educators, requiring a high degree of effort, consistency, and precision. Recent developments in Large Language Models (LLMs)…

Computation and Language · Computer Science 2024-05-10 Jussi S. Jauhiainen , Agustín Garagorry Guerra

This study evaluates the performance of Large Language Models (LLMs) as an Artificial Intelligence-based tutor for a university course. In particular, different advanced techniques are utilized, such as prompt engineering,…

Large language models (LLMs) are transforming research on machine learning while galvanizing public debates. Understanding not only when these models work well and succeed but also why they fail and misbehave is of great societal relevance.…

Computation and Language · Computer Science 2024-10-16 Julian Coda-Forno , Kristin Witte , Akshay K. Jagadish , Marcel Binz , Zeynep Akata , Eric Schulz

The rapid development of large language models (LLMs) has not only provided numerous opportunities but also presented significant challenges. This becomes particularly evident when LLMs inadvertently generate harmful or toxic content,…

Computation and Language · Computer Science 2024-02-20 Kai Chen , Chunwei Wang , Kuo Yang , Jianhua Han , Lanqing Hong , Fei Mi , Hang Xu , Zhengying Liu , Wenyong Huang , Zhenguo Li , Dit-Yan Yeung , Lifeng Shang , Xin Jiang , Qun Liu

The integration of Large Language Models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating drug discovery, and optimizing…

Quantitative Methods · Quantitative Biology 2024-09-10 Yizhen Zheng , Huan Yee Koh , Maddie Yang , Li Li , Lauren T. May , Geoffrey I. Webb , Shirui Pan , George Church

Reinforcement Learning (RL) algorithms often require long training to become useful, especially in complex environments with sparse rewards. While techniques like reward shaping and curriculum learning exist to accelerate training, these…

Machine Learning · Computer Science 2025-09-11 Lukas Toral , Teddy Lazebnik

Background: The radiation oncology clinical practice involves many steps relying on the dynamic interplay of abundant text data. Large language models have displayed remarkable capabilities in processing complex text information. But their…

Recent advances in large language models (LLMs) demonstrate substantial capabilities in natural language understanding and generation tasks. With the growing number of LLMs, how to harness the collective expertise of multiple LLMs is an…

Computation and Language · Computer Science 2024-06-10 Junlin Wang , Jue Wang , Ben Athiwaratkun , Ce Zhang , James Zou

The current work investigates the capability of Large language models (LLMs) that are explicitly trained on large corpuses of medical knowledge (Med-PaLM 2) to predict psychiatric functioning from patient interviews and clinical…

Computation and Language · Computer Science 2023-08-04 Isaac R. Galatzer-Levy , Daniel McDuff , Vivek Natarajan , Alan Karthikesalingam , Matteo Malgaroli

Large language models (LLMs) achieve optimal utility when their responses are grounded in external knowledge sources. However, real-world documents, such as annual reports, scientific papers, and clinical guidelines, frequently combine…

Information Retrieval · Computer Science 2025-12-17 Chi Zhang , Qiyang Chen , Mengqi Zhang

In this paper, we explore the integration of Large Language Models (LLMs) with Retrieval-Augmented Generation (RAG) to enhance automated design and software development in the automotive industry. We present two case studies: a…

Software Engineering · Computer Science 2024-11-15 Vahid Zolfaghari , Nenad Petrovic , Fengjunjie Pan , Krzysztof Lebioda , Alois Knoll

Multilingual large language models (LLMs) possess impressive multilingual understanding and generation capabilities. However, their performance and cross-lingual alignment often lag for non-dominant languages. A common solution is to…

Computation and Language · Computer Science 2025-09-30 Mengyu Bu , Shaolei Zhang , Zhongjun He , Hua Wu , Yang Feng
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