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Intracellular signaling often arises from ligand-induced oligomerization of cell surface receptors. This oligomerization or clustering process is fundamentally a cooperative behavior between near-neighbor receptor molecules; the properties…

Soft Condensed Matter · Physics 2009-10-31 Chinlin Guo , Herbert Levine

We introduce a statistical mechanics formalism for the study of constrained graph evolution as a Markovian stochastic process, in analogy with that available for spin systems, deriving its basic properties and highlighting the role of the…

Disordered Systems and Neural Networks · Physics 2015-05-13 A. C. C. Coolen , A. De Martino , A. Annibale

Mean-field stochastic differential equations, also called McKean--Vlasov equations, are the limiting equations of interacting particle systems with fully symmetric interaction potential. Such systems play an important role in a variety of…

Dynamical Systems · Mathematics 2025-09-15 Eirini Ioannou , Stefan Klus , Gonçalo dos Reis

Structure-based coarse graining of molecular systems offers a systematic route to reproduce the many-body potential of mean force. Unfortunately, common strategies are inherently limited by the molecular mechanics force field employed.…

Soft Condensed Matter · Physics 2018-12-27 Tristan Bereau , Joseph F. Rudzinski

Recent studies have indicated that the coarse grained dynamics of a large class of traffic models and driven-diffusive systems may be described by urn models. We consider a class of one-dimensional urn models whereby particles hop from an…

Statistical Mechanics · Physics 2009-11-10 E. Levine , D. Mukamel , G. Ziv

We review some recent coarse-graining and multi-scale methods, but also put forward some new ideas for addressing such issues. We find that, if one is guided by nonequilibrium statistical mechanics and thermodynamics, it is possible to…

Soft Condensed Matter · Physics 2009-11-06 Patrick Ilg , Vlasis Mavrantzas , Hans Christian Öttinger

We propose a data-driven approach for propagating uncertainty in stochastic power grid simulations and apply it to the estimation of transmission line failure probabilities. A reduced-order equation governing the evolution of the observed…

Computational Engineering, Finance, and Science · Computer Science 2024-01-08 Hongli Zhao , Tyler E. Maltba , D. Adrian Maldonado , Emil Constantinescu , Mihai Anitescu

The application of machine learning methods to particle physics often doesn't provide enough understanding of the underlying physics. An interpretable model which provides a way to improve our knowledge of the mechanism governing a physical…

Computational Physics · Physics 2023-07-19 Marko Jercic , Nikola Poljak

An approach to improve neural network interpretability is via clusterability, i.e., splitting a model into disjoint clusters that can be studied independently. We define a measure for clusterability and show that pre-trained models form…

Machine Learning · Computer Science 2025-07-28 Satvik Golechha , Maheep Chaudhary , Joan Velja , Alessandro Abate , Nandi Schoots

The data stream model has been defined for new classes of applications involving massive data being generated at a fast pace. Web click stream analysis and detection of network intrusions are two examples. Cluster analysis on data streams…

Databases · Computer Science 2007-05-23 Zengyou He , Xiaofei Xu , Shengchun Deng , Joshua Zhexue Huang

Quantum algorithms have the potential to revolutionize our understanding of open quantum systems in chemistry. In this work, we demonstrate that a repeated interaction model, which could serve as the foundation for a digital quantum…

Quantum Physics · Physics 2025-05-05 Lea K. Northcote , Matthew S. Teynor , Gemma C. Solomon

Causal Temporal Representation Learning (Ctrl) methods aim to identify the temporal causal dynamics of complex nonstationary temporal sequences. Despite the success of existing Ctrl methods, they require either directly observing the domain…

Machine Learning · Computer Science 2024-09-06 Xiangchen Song , Zijian Li , Guangyi Chen , Yujia Zheng , Yewen Fan , Xinshuai Dong , Kun Zhang

Coarse-grained (CG) models provide an effective route to reducing the complexity of molecular simulations (MD), but conventional approaches depend heavily on long all-atom MD trajectories to adequately sample configurational space. This…

Chemical Physics · Physics 2025-10-28 Maximilian Stupp , P. S. Koutsourelakis

Transformers are extremely successful machine learning models whose mathematical properties remain poorly understood. Here, we rigorously characterize the behavior of transformers with hardmax self-attention and normalization sublayers as…

Computation and Language · Computer Science 2026-05-14 Albert Alcalde , Giovanni Fantuzzi , Enrique Zuazua

In Robust Control and Data Driven Robust Control design methodologies, multiple plant transfer functions or a family of transfer functions are considered and a common controller is designed such that all the plants that fall into this…

Systems and Control · Electrical Eng. & Systems 2023-11-20 Nikhil Potu Surya Prakash , Joohwan Seo , Jongeun Choi , Roberto Horowitz

Closure models are widely used in simulating complex multiscale dynamical systems such as turbulence and the earth system, for which direct numerical simulation that resolves all scales is often too expensive. For those systems without a…

Machine Learning · Computer Science 2025-04-22 Xinghao Dong , Chuanqi Chen , Jin-Long Wu

We present a quantum algorithm for data classification based on the nearest-neighbor learning algorithm. The classification algorithm is divided into two steps: Firstly, data in the same class is divided into smaller groups with sublabels…

Quantum Physics · Physics 2021-06-15 Junxu Li , Sabre Kais

We provide a numerical study of the macroscopic model of [3] derived from an agent-based model for a system of particles interacting through a dynamical network of links. Assuming that the network remodelling process is very fast, the…

In this paper we focus on the development of new methods suitable for efficient and reliable coarse-graining of {\it non-equilibrium} molecular systems. In this context, we propose error estimation and controlled-fidelity model reduction…

Computational Physics · Physics 2015-06-15 Markos A. Katsoulakis , Petr Plechac

This paper presents CLUSTERFORMER, a universal vision model that is based on the CLUSTERing paradigm with TransFORMER. It comprises two novel designs: 1. recurrent cross-attention clustering, which reformulates the cross-attention mechanism…

Computer Vision and Pattern Recognition · Computer Science 2023-10-09 James C. Liang , Yiming Cui , Qifan Wang , Tong Geng , Wenguan Wang , Dongfang Liu