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Hydration status is a key physiological indicator associated with cellular homeostasis, renal function, and overall health. Recent advances in smart sensing environments enable passive monitoring of urinary biomarkers that can provide…

Quantitative ultrasound (QUS) offers a non-invasive and objective way to quantify tissue health. We recently presented a spatially adaptive regularization method for reconstruction of a single QUS parameter, limited to a two dimensional…

Accurate estimation of a user's biological joint moment from wearable sensor data is vital for improving exoskeleton control during real-world locomotor tasks. However, most state-of-the-art methods rely on deep learning techniques that…

Robotics · Computer Science 2026-03-10 Jimin An , Changseob Song , Eni Halilaj , Inseung Kang

Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity and mortality. While COPD diagnosis is based on lung function tests, early stages and progression of different aspects of the disease can be visible and…

Image and Video Processing · Electrical Eng. & Systems 2019-09-30 Max Argus , Cornelia Schaefer-Prokop , David A. Lynch , Bram van Ginneken

Gaussian processes (GPs) are used to make medical and scientific decisions, including in cardiac care and monitoring of atmospheric carbon dioxide levels. Notably, the choice of GP kernel is often somewhat arbitrary. In particular,…

In recent years, a comprehensive study of multi-view datasets (e.g., multi-omics and imaging scans) has been a focus and forefront in biomedical research. State-of-the-art biomedical technologies are enabling us to collect multi-view…

Machine Learning · Statistics 2020-04-30 Md Ashad Alam , Chuan Qiu , Hui Shen , Yu-Ping Wang , Hong-Wen Deng

The rate of convergence of weighted kernel herding (WKH) and sequential Bayesian quadrature (SBQ), two kernel-based sampling algorithms for estimating integrals with respect to some target probability measure, is investigated. Under…

Machine Learning · Statistics 2021-11-02 Rajiv Khanna , Liam Hodgkinson , Michael W. Mahoney

Gaussian processes (GP) for machine learning have been studied systematically over the past two decades and they are by now widely used in a number of diverse applications. However, GP kernel design and the associated hyper-parameter…

Machine Learning · Computer Science 2020-10-28 Feng Yin , Lishuo Pan , Xinwei He , Tianshi Chen , Sergios Theodoridis , Zhi-Quan , Luo

We propose a quantum algorithm based on ridge regression model, which get the optimal fitting parameters w and a regularization hyperparameter {\alpha} by analysing the training dataset. The algorithm consists of two subalgorithms. One is…

Quantum Physics · Physics 2021-04-28 Menghan Chen , Chaohua Yu , Gongde Guo , Song Lin

Quantitative MRI (qMRI) methods allow reducing the subjectivity of clinical MRI by providing numerical values on which diagnostic assessment or predictions of tissue properties can be based. However, qMRI measurements typically take more…

Medical Physics · Physics 2022-02-15 Matti Hanhela , Antti Paajanen , Mikko J. Nissi , Ville Kolehmainen

High-resolution (HR) quantitative MRI (qMRI) relaxometry provides objective tissue characterization but remains clinically underutilized due to lengthy acquisition times. We propose a physics-informed, self-supervised framework for qMRI…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Alireza Samadifardheris , Dirk H. J. Poot , Florian Wiesinger , Stefan Klein , Juan A. Hernandez-Tamames

Certain cancer types, notably pancreatic cancer, are difficult to detect at an early stage, motivating robust biomarker-based screening. Liquid biopsies enable non-invasive monitoring of circulating biomarkers, but typical machine learning…

Machine Learning · Computer Science 2025-11-21 Chongmin Lee , Jihie Kim

Along with rich health-related metadata, medical images have been acquired for over 40,000 male and female UK Biobank participants, aged 44-82, since 2014. Phenotypes derived from these images, such as measurements of body composition from…

Image and Video Processing · Electrical Eng. & Systems 2021-09-16 Taro Langner , Fredrik K. Gustafsson , Benny Avelin , Robin Strand , Håkan Ahlström , Joel Kullberg

Multimodal self-supervised pretraining offers a promising route to cancer prognosis by integrating histopathology whole-slide images, gene expression, and pathology reports, yet most existing approaches require fully paired and complete…

Machine Learning · Computer Science 2026-04-08 Kai Yu , Shuang Zhou , Yiran Song , Zaifu Zhan , Jie Peng , Kaixiong Zhou , Tianlong Chen , Feng Xie , Meng Wang , Huazhu Fu , Mingquan Lin , Rui Zhang

Multimodal imaging has transformed neuroscience research. While it presents unprecedented opportunities, it also imposes serious challenges. Particularly, it is difficult to combine the merits of the interpretability attributed to a simple…

Methodology · Statistics 2021-11-25 Xiaowu Dai , Lexin Li

A major challenge in machine learning is the computational expense of training these models. Model training can be viewed as a form of optimization used to fit a machine learning model to a set of data, which can take up significant amount…

Machine Learning · Computer Science 2021-11-16 Prasanna Date , Thomas Potok

Foundation models pretrained on large-scale histopathology data have found great success in various fields of computational pathology, but their impact on regressive biomarker prediction remains underexplored. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Alexander Blezinger , Wolfgang Nejdl , Ming Tang

Instant machine learning predictions of molecular properties are desirable for materials design, but the predictive power of the methodology is mainly tested on well-known benchmark datasets. Here, we investigate the performance of machine…

Advances in classical machine learning and single-cell technologies have paved the way to understand interactions between disease cells and tumor microenvironments to accelerate therapeutic discovery. However, challenges in these machine…

Quantum Physics · Physics 2023-10-18 Anupama Ray , Dhiraj Madan , Srushti Patil , Maria Anna Rapsomaniki , Pushpak Pati

Effective molecular representations are essential for ligand-based virtual screening. We investigate how quantum data embedding strategies can improve this task by developing and evaluating a family of quantum-classical hybrid embedding…

Quantum Physics · Physics 2025-12-19 Junggu Choi , Tak Hur , Seokhoon Jeong , Kyle L. Jung , Jun Bae Park , Junho Lee , Jae U. Jung , Daniel K. Park