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We introduce a model for describing the dynamics of large numbers of interacting cells. The fundamental dynamical variables in the model are sub-cellular elements, which interact with each other through phenomenological intra- and…

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Starting from the concept of binary interactions between pairs of particles, a kinetic framework for the description of the action potential dynamics on a neural network is proposed. It consists of two coupled levels: the description of a…

Biological Physics · Physics 2023-03-21 Martina Conte , Maria Groppi , Andrea Tosin

Defining cellular sheaves beyond graph structures, such as on simplicial complexes containing higher-dimensional simplices, is an essential and intriguing topic in topological data analysis (TDA) and the development of sheaf neural…

Algebraic Topology · Mathematics 2025-07-02 Chuan-Shen Hu

Composition is a powerful principle for systems biology, focused on the interfaces, interconnections, and orchestration of distributed processes to enable integrative multiscale simulations. Whereas traditional models focus on the structure…

Other Quantitative Biology · Quantitative Biology 2024-11-25 Eran Agmon

Recent advances in cellular research demonstrate that scRNA-seq characterizes cellular heterogeneity, while spatial transcriptomics reveals the spatial distribution of gene expression. Cell representation is the fundamental issue in the two…

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Soft materials (e.g., enveloped viruses, liposomes, membranes and supercooled liquids) simultaneously deform or display collective behaviors, while undergoing atomic scale vibrations and collisions. While the multiple space-time character…

Soft Condensed Matter · Physics 2014-01-03 Peter Ortoleva , Abhishek Singharoy , Stephen Pankavich

We construct algorithms and topological invariants that allow us to distinguish the topological type of a surface, as well as functions and vector fields for their topological equivalence. In the first part we discus the main structures…

Dynamical Systems · Mathematics 2025-01-28 Alexandr Prishlyak

Living systems exhibit complex yet organized behavior on multiple spatiotemporal scales. To investigate the nature of multiscale coordination in living systems, one needs a meaningful and systematic way to quantify the complex dynamics, a…

Adaptation and Self-Organizing Systems · Physics 2020-03-11 Mengsen Zhang , William D. Kalies , J. A. Scott Kelso , Emmanuelle Tognoli

Presenting systems of differential equations in the form of diagrams has become common in certain parts of physics, especially electromagnetism and computational physics. In this work, we aim to put such use of diagrams on a firm…

Mathematical Physics · Physics 2022-06-20 Evan Patterson , Andrew Baas , Timothy Hosgood , James Fairbanks

The present work proposes an approach for fluid-solid and contact interaction problems including thermo-mechanical coupling and reversible phase transitions. The solid field is assumed to consist of several arbitrarily-shaped, undeformable…

Computational Engineering, Finance, and Science · Computer Science 2021-09-14 Sebastian L. Fuchs , Christoph Meier , Wolfgang A. Wall , Christian J. Cyron

Complex geometric tasks such as geometric modeling, physical simulation, and texture parametrization often involve the embedding of many complex sub-domains with potentially different dimensions. These tasks often require evolving the…

Graphics · Computer Science 2025-01-03 Michael Tao , Jiacheng Dai , Denis Zorin , Teseo Schneider , Daniele Panozzo

Membrane computing is a well-established and successful research field which belongs to the more general area of molecular computing. Membrane computing aims at defining parallel and non-deterministic computing models, called membrane…

Distributed, Parallel, and Cluster Computing · Computer Science 2011-08-11 Bogdan Aman

The problem of membrane topology in the matrix model of M-theory is considered. The matrix regularization procedure, which makes a correspondence between finite-sized matrices and functions defined on a two-dimensional base space, is…

High Energy Physics - Theory · Physics 2010-04-05 H. Shimada

We firstly introduce some key concepts in category theory, such as quotient category, completion of limits, $\mathrm{Mor}$ category, and so on; then give the concept of topology algebras and sheaves, and discuss how to restore the structue…

Category Theory · Mathematics 2019-06-11 Dezhao Zhang

Phase-field methods offer a versatile computational framework for simulating large-scale morphological evolution. However, the applicability and predictability of phase-field models are inherently limited by their ad hoc nature, and there…

Materials Science · Physics 2025-10-30 Jaehyeok Jin , David R. Reichman

We introduce a hierarchical categorical framework for Schema-Based Learning (SBL) structured across four interconnected levels. At the schema level, a free multicategory $Sch_{syn}$ encodes fundamental schemas and transformations. An…

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Sheaves and sheaf cohomology are powerful tools in computational topology, greatly generalizing persistent homology. We develop an algorithm for simplifying the computation of cellular sheaf cohomology via (discrete) Morse-theoretic…

Algebraic Topology · Mathematics 2015-04-09 Justin Curry , Robert Ghrist , Vidit Nanda

Canonical quantization of abelian BF-type topological field theory coupled to extended sources on generic d-dimensional manifolds and with curved line bundles is studied. Sheaf cohomology is used to construct the appropriate topological…

High Energy Physics - Theory · Physics 2011-07-19 Richard J. Szabo

This study introduces a pore morphology algorithm that emphasizes the central role of topology in multiphase flow through porous media. Analysis of drainage in lattice-based pore networks identifies two key quantities, the percolation…

Statistical Mechanics · Physics 2025-08-27 Fernando Alonso-Marroquin

Every small monoidal category with universal finite joins of central idempotents is monoidally equivalent to the category of global sections of a sheaf of local monoidal categories on a topological space. Every small stiff monoidal category…

Category Theory · Mathematics 2023-02-09 Rui Soares Barbosa , Chris Heunen