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The structure of topological spaces is analysed here through the lenses of fibrous preorders. Each topological space has an associated fibrous preorder and those fibrous preorders which return a topological space are called spacial. A…

General Topology · Mathematics 2021-02-22 Nelson Martins-Ferreira

In many scenarios, especially biomedical applications, the correct delineation of complex fine-scaled structures such as neurons, tissues, and vessels is critical for downstream analysis. Despite the strong predictive power of deep learning…

Computer Vision and Pattern Recognition · Computer Science 2024-03-25 Xiaoling Hu

As data grows in size and complexity, finding frameworks which aid in interpretation and analysis has become critical. This is particularly true when data comes from complex systems where extensive structure is available, but must be drawn…

Machine Learning · Computer Science 2021-05-24 Henry Kvinge , Brett Jefferson , Cliff Joslyn , Emilie Purvine

Complexes and cohomology, traditionally central to topology, have emerged as fundamental tools across applied mathematics and the sciences. This survey explores their roles in diverse areas, from partial differential equations and continuum…

Numerical Analysis · Mathematics 2025-10-21 Kaibo Hu

The processes taking place inside the living cell are now understood to the point where predictive computational models can be used to gain detailed understanding of important biological phenomena. A key challenge is to extrapolate this…

Tissues and Organs · Quantitative Biology 2018-10-26 Stefan Engblom Daniel B. Wilson , Ruth E. Baker

This paper investigates spaces equipped with a family of metric-like functions satisfying certain axioms. These functions provide a unified framework for defining topology, uniformity, and diffeology. The framework is based on a family of…

General Topology · Mathematics 2026-03-25 Masaki Taho

A categorical framework for modeling and analyzing systems in a broad sense is proposed. These systems should be thought of as `machines' with inputs and outputs, carrying some sort of signal that occurs through some notion of time. Special…

Category Theory · Mathematics 2019-03-18 Patrick Schultz , David I. Spivak , Christina Vasilakopoulou

In this paper, we aim at modelling and analyzing the regulation processes in multi-cellular biological systems, in particular tissues. The modelling framework is based on interconnected logical regulatory networks a la Rene Thomas equipped…

Computational Engineering, Finance, and Science · Computer Science 2010-11-08 Jean-Louis Giavitto , Hanna Klaudel , Franck Pommereau

In this work, we present a multiscale kinetic framework for consensus-based image segmentation. By interpreting an image as a system of interacting particles, each pixel is characterised by its spatial position and an internal feature…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Horacio Tettamanti , Giulia Guicciardi , Mattia Zanella

We introduce a sheaf-theoretic characterization of task solvability in general distributed computing models, unifying distinct approaches to message-passing models. We establish cellular sheaves as a natural mathematical framework for…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-08-28 Stephan Felber , Bernardo Hummes Flores , Hugo Rincon Galeana

During developmental processes such as embryogenesis, how a group of cells fold into specific structures, is a central question in biology that defines how living organisms form. Establishing tissue-level morphology critically relies on how…

Soft Condensed Matter · Physics 2024-07-23 Haiqian Yang , Anh Q. Nguyen , Dapeng Bi , Markus J. Buehler , Ming Guo

Three-dimensional magnetic textures, such as Hopfions, torons, and skyrmion tubes, possess rich geometric and topological structure, but their detailed energetics, deformation modes, and collective behavior are yet to be fully understood.…

Mesoscale and Nanoscale Physics · Physics 2025-09-19 Jacob Mankenberg , Artem Abanov

A distinguishing feature of a multicellular living system is that it operates at various scales, from the intracellular to organismal. Very little is known at present on how tissue level properties are related to cell and subcellular…

Biological Physics · Physics 2007-06-26 Elijah Flenner , Francoise Marga , Adrian Neagu , Ioan Kosztin , Gabor Forgacs

Mechanisms are a fundamental concept in many areas of science. Nonetheless, there has been little effort to develop structures to represent mechanisms. We explore the issues in developing a basic semantic modeling framework for describing…

Digital Libraries · Computer Science 2019-01-01 Robert B Allen

We present a unified framework to systematically embed complex knotted and linked structures, beyond the torus family, into diverse topological phases, including Hopf insulators, classical spin liquids, topological semimetals, and…

Strongly Correlated Electrons · Physics 2025-03-27 Snigdh Sabharwal

Multiplexed imaging allows multiple cell types to be simultaneously visualised in a single tissue sample, generating unprecedented amounts of spatially-resolved, biological data. In topological data analysis, persistent homology provides…

Quantitative Methods · Quantitative Biology 2025-05-06 Maria Torras-Pérez , Iris H. R. Yoon , Praveen Weeratunga , Ling-Pei Ho , Helen M. Byrne , Ulrike Tillmann , Heather A. Harrington

The transport of particles across lipid-bilayer membranes is important for biological cells to exchange information and material with their environment. Large particles often get wrapped by membranes, a process which has been intensively…

Soft Condensed Matter · Physics 2024-06-04 Jiarul Midya , Thorsten Auth , Gerhard Gompper

Understanding the context of complex and cluttered scenes is a challenging problem for semantic segmentation. However, it is difficult to model the context without prior and additional supervision because the scene's factors, such as the…

Computer Vision and Pattern Recognition · Computer Science 2021-04-06 Hiroaki Aizawa , Yukihiro Domae , Kunihito Kato

The main goal of this paper is to establish close relations among sheaves of modules on atomic sites, representations of categories, and discrete representations of topological groups. We characterize sheaves of modules on atomic sites as…

Representation Theory · Mathematics 2025-05-07 Zhenxing Di , Liping Li , Li Liang , Fei Xu

The cohomology theory known as Tmf, for "topological modular forms," is a universal object mapping out to elliptic cohomology theories, and its coefficient ring is closely connected to the classical ring of modular forms. We extend this to…

Algebraic Topology · Mathematics 2015-02-05 Michael Hill , Tyler Lawson