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The histological assessment of human tissue has emerged as the key challenge for detection and treatment of cancer. A plethora of different data sources ranging from tissue microarray data to gene expression, proteomics or metabolomics data…

Computer Vision and Pattern Recognition · Computer Science 2016-01-05 Thomas J. Fuchs , Joachim M. Buhmann

While Vision-Language Models (VLMs) have achieved notable progress in computational pathology (CPath), the gigapixel scale and spatial heterogeneity of Whole Slide Images (WSIs) continue to pose challenges for multimodal understanding.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Fengchun Liu , Songhan Jiang , Linghan Cai , Ziyue Wang , Yongbing Zhang

The role of artificial intelligence (AI) in pathology has evolved from aiding diagnostics to uncovering predictive morphological patterns in whole slide images (WSIs). Recently, foundation models (FMs) leveraging self-supervised…

Continuous physiological monitoring is central to emergency care, yet deploying trustworthy AI is challenging. While LLMs can translate complex physiological signals into clinical narratives, it is unclear how agentic systems perform…

Machine Learning · Computer Science 2026-03-05 Davide Gabrielli , Paola Velardi , Stefano Faralli , Bardh Prenkaj

Despite being widely used to support clinical care, general-purpose large multimodal models (LMMs) have generally shown poor or inconclusive performance in medical image interpretation, particularly in pathology, where gigapixel images are…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Thomas A. Buckley , Kian R. Weihrauch , Katherine Latham , Andrew Z. Zhou , Padmini A. Manrai , Arjun K. Manrai

With the development of digital imaging in medical microscopy, artificial intelligent-based analysis of pathological whole slide images (WSIs) provides a powerful tool for cancer diagnosis. Limited by the expensive cost of pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Jiawen Li , Qiehe Sun , Renao Yan , Yizhi Wang , Yuqiu Fu , Yani Wei , Tian Guan , Huijuan Shi , Yonghonghe He , Anjia Han

Large language models (LLMs) and agentic systems have shown promise for clinical decision support, but existing works largely assume that evidence has already been curated and handed to the model. Real-world clinical workflows instead…

Computation and Language · Computer Science 2026-05-20 Juncheng Wu , Letian Zhang , Yuhan Wang , Haoqin Tu , Hardy Chen , Zijun Wang , Cihang Xie , Yuyin Zhou

Radiology reporting generative AI holds significant potential to alleviate clinical workloads and streamline medical care. However, achieving high clinical accuracy is challenging, as radiological images often feature subtle lesions and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Yijian Gao , Dominic Marshall , Xiaodan Xing , Junzhi Ning , Giorgos Papanastasiou , Guang Yang , Matthieu Komorowski

Early identification of stroke symptoms is essential for enabling timely intervention and improving patient outcomes, particularly in prehospital settings. This study presents a fast, non-invasive multimodal deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Ngoc-Khai Hoang , Thi-Nhu-Mai Nguyen , Huy-Hieu Pham

The complexity and variability inherent in high-resolution pathological images present significant challenges in computational pathology. While pathology foundation models leveraging AI have catalyzed transformative advancements, their…

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

The integration of Large Language Models (LLMs) into healthcare is constrained by knowledge limitations, hallucinations, and a disconnect from Evidence-Based Medicine (EBM). While Retrieval-Augmented Generation (RAG) offers a solution,…

Computation and Language · Computer Science 2026-02-03 Qiaoyu Zheng , Yuze Sun , Chaoyi Wu , Weike Zhao , Pengcheng Qiu , Yongguo Yu , Kun Sun , Jian Zhang , Yanfeng Wang , Ya Zhang , Weidi Xie

Information gathering in large-scale or time-critical scenarios (e.g., environmental monitoring, search and rescue) requires broad coverage within limited time budgets, motivating the use of multi-agent systems. These scenarios are commonly…

Robotics · Computer Science 2026-05-01 Jeric Lew , Yuhong Cao , Derek Ming Siang Tan , Guillaume Sartoretti

Multimodal Stance Detection (MSD) is crucial for understanding public discourse, yet effectively fusing text and image, especially with conflicting signals, remains challenging. Existing methods often face difficulties with contextual…

Artificial Intelligence · Computer Science 2026-05-01 Weihai Lu , Zhejun Zhao , Yanshu Li , Huan He

Pathologists diagnose cancer using gigapixel whole-slide images (WSIs), but the current digital workflow is fragmented. These multiscale datasets often exceed 100,000 x 100,000 pixels, yet standard 2D monitors restrict the field of view.…

Human-Computer Interaction · Computer Science 2026-02-27 Jai Prakash Veerla , Partha Sai Guttikonda , Helen H. Shang , Mohammad Sadegh Nasr , Cesar Torres , Jacob M. Luber

Multimodal foundation models have significantly improved feature representation by integrating information from multiple modalities, making them highly suitable for a broader set of applications. However, the exploration of multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Kaiwen Zheng , Xuri Ge , Junchen Fu , Jun Peng , Joemon M. Jose

Multimodal machine learning is a vibrant multi-disciplinary research field that aims to design computer agents with intelligent capabilities such as understanding, reasoning, and learning through integrating multiple communicative…

Machine Learning · Computer Science 2023-02-21 Paul Pu Liang , Amir Zadeh , Louis-Philippe Morency

Efficiently navigating complex environments requires agents to internalize the underlying logic of their world, yet standard world modelling methods often struggle with sample inefficiency, lack of transparency, and poor scalability. We…

Artificial Intelligence · Computer Science 2026-02-20 Enrique Crespo-Fernandez , Oliver Ray , Telmo de Menezes e Silva Filho , Peter Flach

Diffusion-based generative models have shown promise in synthesizing histopathology images to address data scarcity caused by privacy constraints. Diagnostic text reports provide high-level semantic descriptions, and masks offer…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Mahesh Bhosale , Abdul Wasi , Yuanhao Zhai , Yunjie Tian , Samuel Border , Nan Xi , Pinaki Sarder , Junsong Yuan , David Doermann , Xuan Gong

Multimodal foundation models offer promising advancements for enhancing driving perception systems, but their high computational and financial costs pose challenges. We develop a method that leverages foundation models to refine predictions…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Yunhao Yang , Yuxin Hu , Mao Ye , Zaiwei Zhang , Zhichao Lu , Yi Xu , Ufuk Topcu , Ben Snyder