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The rapid evolution of AI-generated images poses growing challenges to information integrity and media authenticity. Existing detection approaches face limitations in robustness, interpretability, and generalization across diverse…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Mengfei Liang , Yiting Qu , Yukun Jiang , Michael Backes , Yang Zhang

While interpretable prototype networks offer compelling case-based reasoning for clinical diagnostics, their raw continuous outputs lack the semantic structure required for medical documentation. Bridging this gap via standard…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Alvaro Lopez Pellicer , Plamen Angelov , Marwan Bukhari , Yi Li , Eduardo Soares , Jemma Kerns

This study proposes a novel approach combining Multimodal Deep Learning with intrinsic eXplainable Artificial Intelligence techniques to predict pathological response in non-small cell lung cancer patients undergoing neoadjuvant therapy.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Alice Natalina Caragliano , Claudia Tacconi , Carlo Greco , Lorenzo Nibid , Edy Ippolito , Michele Fiore , Giuseppe Perrone , Sara Ramella , Paolo Soda , Valerio Guarrasi

Deep models that are both effective and explainable are desirable in many settings; prior explainable models have been unimodal, offering either image-based visualization of attention weights or text-based generation of post-hoc…

Artificial Intelligence · Computer Science 2018-02-23 Dong Huk Park , Lisa Anne Hendricks , Zeynep Akata , Anna Rohrbach , Bernt Schiele , Trevor Darrell , Marcus Rohrbach

Artificial intelligence (AI)-enabled diagnostics in maxillofacial pathology require structured, high-quality multimodal datasets. However, existing resources provide limited ameloblastoma coverage and lack the format consistency needed for…

Artificial Intelligence · Computer Science 2026-02-06 Ajo Babu George , Anna Mariam John , Athul Anoop , Balu Bhasuran

Pathological assessment guides lung cancer diagnosis, treatment selection, and prognostic evaluation, yet current CPath approaches rely on task-specific models for isolated objectives. Although pan-cancer foundation models offer…

Automated fact-checking is a crucial task that supports a responsible information ecosystem. While recent research has progressed from text-only to multimodal fact-checking, a prevailing assumption is that incorporating visual evidence…

Computation and Language · Computer Science 2026-05-14 Jaeyoon Jung , Yejun Yoon , Kunwoo Park

Foundation models are reshaping computational pathology by enabling transfer learning, where models pre-trained on vast datasets can be adapted for downstream diagnostic, prognostic, and therapeutic response tasks. Despite these advances,…

Retinal diseases spanning a broad spectrum can be effectively identified and diagnosed using complementary signals from multimodal data. However, multimodal diagnosis in ophthalmic practice is typically challenged in terms of data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Lu Zhang , Huizhen Yu , Zuowei Wang , Fu Gui , Yatu Guo , Wei Zhang , Mengyu Jia

Prevalent in biomedical applications (e.g., human phenotype research), multimodal datasets can provide valuable insights into the underlying physiological mechanisms. However, current machine learning (ML) models designed to analyze these…

Computational pathology demands both visual pattern recognition and dynamic integration of structured domain knowledge, including taxonomy, grading criteria, and clinical evidence. In practice, diagnostic reasoning requires linking…

Artificial Intelligence · Computer Science 2026-05-26 Jinyue Li , Yuci Liang , Qiankun Li , Xinheng Lyu , Jiayu Qian , Huabao Chen , Kun Wang , Zhigang Zeng , Anil Anthony Bharath , Yang Liu

Oral cancer is frequently diagnosed at later stages due to its similarity to other lesions. Existing research on computer aided diagnosis has made progress using deep learning; however, most approaches remain limited by small, imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Joy Naoum , Revana Salama , Ali Hamdi

Although numerous strategies have recently been proposed to enhance the autonomous interaction capabilities of multimodal agents in graphical user interface (GUI), their reliability remains limited when faced with complex or out-of-domain…

Computation and Language · Computer Science 2025-10-06 Pengzhou Cheng , Lingzhong Dong , Zeng Wu , Zongru Wu , Xiangru Tang , Chengwei Qin , Zhuosheng Zhang , Gongshen Liu

Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…

Computer Vision and Pattern Recognition · Computer Science 2019-10-30 Aïcha BenTaieb , Ghassan Hamarneh

In medical imaging, particularly in early disease detection and prognosis tasks, discerning the rationale behind an AI model's predictions is crucial for evaluating the reliability of its decisions. Conventional explanation methods face…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Yingying Fang , Zihao Jin , Xiaodan Xing , Simon Walsh , Guang Yang

In science, we are interested not only in forecasting but also in understanding how predictions are made, specifically what the interpretable underlying model looks like. Data-driven machine learning technology can significantly streamline…

Symbolic Computation · Computer Science 2025-05-29 Weiting Liu , Jiaxu Cui , Jiao Hu , En Wang , Bo Yang

Deciphering tumor microenvironment from Whole Slide Images (WSIs) is intriguing as it is key to cancer diagnosis, prognosis and treatment response. While these gigapixel images on one hand offer a comprehensive portrait of cancer, on the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Kunpeng Zhang , Hanwen Xu , Sheng Wang

In the field of image-based drug discovery, capturing the phenotypic response of cells to various drug treatments and perturbations is a crucial step. However, existing methods require computationally extensive and complex multi-step…

Machine Learning · Computer Science 2025-02-28 Bo Li , Bob Zhang , Chengyang Zhang , Minghao Zhou , Weiliang Huang , Shihang Wang , Qing Wang , Mengran Li , Yong Zhang , Qianqian Song

In the health domain, decisions are often based on different data modalities. Thus, when creating prediction models, multimodal fusion approaches that can extract and combine relevant features from different data modalities, can be highly…

Artificial Intelligence · Computer Science 2024-02-20 Mafalda Malafaia , Thalea Schlender , Peter A. N. Bosman , Tanja Alderliesten

Healthcare foundation models have largely followed paradigms from natural language processing and computer vision, emphasizing large scale pretraining and deterministic representations over heterogeneous clinical data. However, clinical…

Machine Learning · Computer Science 2026-04-07 Qian Zhou , Yuanyun Zhang , Shi Li
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