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The process of screening molecules for desirable properties is a key step in several applications, ranging from drug discovery to material design. During the process of drug discovery specifically, protein-ligand docking, or chemical…

Machine Learning · Computer Science 2022-11-08 Ryien Hosseini , Filippo Simini , Austin Clyde , Arvind Ramanathan

Hierarchical matrices provide a powerful representation for significantly reducing the computational complexity associated with dense kernel matrices. For general kernel functions, interpolation-based methods are widely used for the…

Numerical Analysis · Mathematics 2022-06-07 Difeng Cai , Hua Huang , Edmond Chow , Yuanzhe Xi

Due to the over-smoothing issue, most existing graph neural networks can only capture limited dependencies with their inherently finite aggregation layers. To overcome this limitation, we propose a new kind of graph convolution, called…

Machine Learning · Computer Science 2022-06-30 Qi Chen , Yifei Wang , Yisen Wang , Jiansheng Yang , Zhouchen Lin

Sim-to-real transfer remains a significant challenge in soft robotics due to the unpredictability introduced by common manufacturing processes such as 3D printing and molding. These processes often result in deviations from simulated…

We develop and analyze a stochastic genetic interacting particle method (SGIP) for reaction-diffusion-advection (RDA) equations. The SGIP method employs operator splitting to approximate the advection-diffusion and reaction processes,…

Numerical Analysis · Mathematics 2026-01-07 Boyi Hu , Zhongjian Wang , Jack Xin , Zhiwen Zhang

We investigate the rate of convergence of linear sampling numbers of the embedding $H^{\alpha,\beta} (\mathbb{T}^d) \hookrightarrow H^\gamma (\mathbb{T}^d)$. Here $\alpha$ governs the mixed smoothness and $\beta$ the isotropic smoothness in…

Numerical Analysis · Mathematics 2014-08-18 Glenn Byrenheid , Dinh Dũng , Winfried Sickel , Tino Ullrich

We present the sliding basis computational framework to automatically synthesize heterogeneous (graded or discrete) material fields for parts designed using constrained optimization. Our framework uses the fact that any spatially varying…

Computational Engineering, Finance, and Science · Computer Science 2020-05-19 Nurcan Gecer Ulu , Svyatoslav Korneev , Erva Ulu , Saigopal Nelaturi

Temporal Interaction Graphs (TIGs) are widely employed to model intricate real-world systems such as financial systems and social networks. To capture the dynamism and interdependencies of nodes, existing TIG embedding models need to…

Machine Learning · Computer Science 2023-09-12 Xi Chen , Yongxiang Liao , Yun Xiong , Yao Zhang , Siwei Zhang , Jiawei Zhang , Yiheng Sun

Graph representation learning seeks to transform complex, high-dimensional graph structures into compact vector spaces that preserve both topology and semantics. Among the various strategies, subgraph-based methods provide an interpretable…

Machine Learning · Computer Science 2025-12-05 Yeamin Kaiser , Muhammed Tasnim Bin Anwar , Bholanath Das

Photopolymerization enables the production of micro-optical elements, such as diffractive optical elements or GRIN optics. This process utilizes targeted spatial modulation of the refractive index, which is achieved through additive…

Optics · Physics 2026-03-16 Andreas Heinrich , Manuel Rank

Topology optimization is one of the engineering tools for finding efficient design. For the material interpolation scheme, it is usual to employ the SIMP (Solid Isotropic Material with Penalization) or the homogenization based interpolation…

Computational Engineering, Finance, and Science · Computer Science 2022-12-07 Bing Yi , Gil Ho Yoon , Ran Zheng , Long Liu , Daping Li , Xiang Peng

Pose graph optimization is a non-convex optimization problem encountered in many areas of robotics perception. Its convergence to an accurate solution is conditioned by two factors: the non-linearity of the cost function in use and the…

Robotics · Computer Science 2022-07-05 Tiziano Guadagnino , Luca Di Giammarino , Giorgio Grisetti

Graph generation generally aims to create new graphs that closely align with a specific graph distribution. Existing works often implicitly capture this distribution through the optimization of generators, potentially overlooking the…

Machine Learning · Computer Science 2024-07-19 Song Wang , Zhen Tan , Xinyu Zhao , Tianlong Chen , Huan Liu , Jundong Li

Chiplet-based systems, integrating various silicon dies manufactured at different integrated circuit technology nodes on a carrier interposer, have garnered significant attention in recent years due to their cost-effectiveness and…

Machine Learning · Computer Science 2024-04-09 Zhihui Deng , Yuanyuan Duan , Leilai Shao , Xiaolei Zhu

Rapid growth in scientific data and a widening gap between computational speed and I/O bandwidth make it increasingly infeasible to store and share all data produced by scientific simulations. Instead, we need methods for reducing data…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-03-02 Jieyang Chen , Lipeng Wan , Xin Liang , Ben Whitney , Qing Liu , David Pugmire , Nicholas Thompson , Matthew Wolf , Todd Munson , Ian Foster , Scott Klasky

Graph Neural Networks (GNNs) with numerical node features and graph structure as inputs have demonstrated superior performance on various supervised learning tasks with graph data. However the numerical node features utilized by GNNs are…

Machine Learning · Computer Science 2022-06-20 Jiuhai Chen , Jonas Mueller , Vassilis N. Ioannidis , Tom Goldstein , David Wipf

Following the success of convolution on non-Euclidean space, the corresponding pooling approaches have also been validated on various tasks regarding graphs. However, because of the fixed compression quota and stepwise pooling design, these…

Machine Learning · Computer Science 2022-06-29 Junran Wu , Xueyuan Chen , Ke Xu , Shangzhe Li

Retrieval-Augmented Generation (RAG) enhances large language models (LLMs) by integrating external knowledge retrieval but faces challenges on edge devices due to high storage, energy, and latency demands. Computing-in-Memory (CIM) offers a…

Genome assembly is a prominent problem studied in bioinformatics, which computes the source string using a set of its overlapping substrings. Classically, genome assembly uses assembly graphs built using this set of substrings to compute…

Data Structures and Algorithms · Computer Science 2024-09-24 Saumya Talera , Parth Bansal , Shabnam Khan , Shahbaz Khan

Graph embedding approaches attempt to project graphs into geometric entities, i.e, manifolds. The idea is that the geometric properties of the projected manifolds are helpful in the inference of graph properties. However, if the choice of…

Computational Geometry · Computer Science 2024-08-01 Saloua Naama , Kavé Salamatian , Francesco Bronzino