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Adaptive subgroup enrichment design is an efficient design framework that allows accelerated development for investigational treatments while also having flexibility in population selection within the course of the trial. The adaptive…

Methodology · Statistics 2022-10-21 Liwen Wu , Qing Li , Mengya Liu , Jianchang Lin

The `spotoptim` package implements surrogate-model-based optimization of expensive black-box functions in Python. Building on two decades of Sequential Parameter Optimization (SPO) methodology, it provides a Kriging-based optimization loop…

Machine Learning · Computer Science 2026-04-16 Thomas Bartz-Beielstein

Time Series Forecasting (TSF) is a crucial task in various domains, yet existing TSF models rely heavily on high-quality data and insufficiently exploit all available data. This paper explores a novel self-supervised approach to re-label…

Machine Learning · Computer Science 2025-12-17 Yuxuan Yang , Dalin Zhang , Yuxuan Liang , Hua Lu , Gang Chen , Huan Li

We present a hybrid sampling-surrogate approach for reducing the computational expense of uncertainty quantification in nonlinear dynamical systems. Our motivation is to enable rapid uncertainty quantification in complex mechanical systems…

Computation · Statistics 2022-01-27 Hang Yang , Yuji Fujii , K. W. Wang , Alex A. Gorodetsky

Anomaly detection in time-series has a wide range of practical applications. While numerous anomaly detection methods have been proposed in the literature, a recent survey concluded that no single method is the most accurate across various…

Machine Learning · Computer Science 2023-03-14 Mononito Goswami , Cristian Challu , Laurent Callot , Lenon Minorics , Andrey Kan

Active statistical inference is a new method for inference with AI-assisted data collection. Given a budget on the number of labeled data points that can be collected and assuming access to an AI predictive model, the basic idea is to…

Machine Learning · Statistics 2025-11-13 Puheng Li , Tijana Zrnic , Emmanuel Candès

Surrogate endpoints are used in place of long-term outcomes in randomized experiments when observing the real outcome for a large enough cohort is prohibitively expensive or impractical. A short-term surrogate is good if the result of an…

Semi supervised learning methods have gained importance in today's world because of large expenses and time involved in labeling the unlabeled data by human experts. The proposed hybrid approach uses SVM and Label Propagation to label the…

Machine Learning · Computer Science 2015-12-08 Aruna Govada , Pravin Joshi , Sahil Mittal , Sanjay K Sahay

Fine tuning self supervised pretrained models using pseudo labels can effectively improve speech recognition performance. But, low quality pseudo labels can misguide decision boundaries and degrade performance. We propose a simple yet…

Sound · Computer Science 2022-11-01 Zezhong Jin , Dading Zhong , Xiao Song , Zhaoyi Liu , Naipeng Ye , Qingcheng Zeng

Multifidelity surrogate modelling combines data of varying accuracy and cost from different sources. It strategically uses low-fidelity models for rapid evaluations, saving computational resources, and high-fidelity models for detailed…

Machine Learning · Computer Science 2024-04-24 Daniel N Wilke

Prior knowledge and symbolic rules in machine learning are often expressed in the form of label constraints, especially in structured prediction problems. In this work, we compare two common strategies for encoding label constraints in a…

Machine Learning · Computer Science 2023-07-11 Kaifu Wang , Hangfeng He , Tin D. Nguyen , Piyush Kumar , Dan Roth

Reasoning on large and complex real-world models is a computationally difficult task, yet one that is required for effective use of many AI applications. A plethora of inference algorithms have been developed that work well on specific…

Artificial Intelligence · Computer Science 2016-06-13 Avi Pfeffer , Brian Ruttenberg , William Kretschmer

Scalable and accurate identification of specific clinical outcomes has been enabled by machine-learning applied to electronic medical record (EMR) systems. The development of classification models requires the collection of a complete…

Methodology · Statistics 2020-11-09 W. Katherine Tan , Patrick J. Heagerty

Over-parameterized deep models usually over-fit to a given training distribution, which makes them sensitive to small changes and out-of-distribution samples at inference time, leading to low generalization performance. To this end, several…

Computer Vision and Pattern Recognition · Computer Science 2019-12-12 Saeid Asgari Taghanaki , Kumar Abhishek , Ghassan Hamarneh

Traditional semi-supervised learning (SSL) assumes that the feature distributions of labeled and unlabeled data are consistent which rarely holds in realistic scenarios. In this paper, we propose a novel SSL setting, where unlabeled samples…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Jiachen Liang , Ruibing Hou , Hong Chang , Bingpeng Ma , Shiguang Shan , Xilin Chen

Explainable AI is a crucial component for edge services, as it ensures reliable decision making based on complex AI models. Surrogate models are a prominent approach of XAI where human-interpretable models, such as a linear regression…

Machine Learning · Computer Science 2025-03-12 Foivos Charalampakos , Thomas Tsouparopoulos , Iordanis Koutsopoulos

The present paper proposes a Bayesian framework for inverse problems that seamlessly integrates optimization and inversion to enable rapid surrogate modeling, accurate parameter inference, and rigorous uncertainty quantification. Bayesian…

Computational Engineering, Finance, and Science · Computer Science 2026-02-05 Mihaela Chiappetta , Massimo Carraturo , Alexander Raßloff , Markus Kästner , Ferdinando Auricchio

Existing deep learning-based surrogate models facilitate efficient data generation, but fall short in uncertainty quantification, efficient parameter space exploration, and reverse prediction. In our work, we introduce SurroFlow, a novel…

Machine Learning · Computer Science 2024-07-19 Jingyi Shen , Yuhan Duan , Han-Wei Shen

Surrogate models are often used as computationally efficient approximations to complex simulation models, enabling tasks such as solving inverse problems, sensitivity analysis, and probabilistic forward predictions, which would otherwise be…

Machine Learning · Statistics 2026-05-13 Philipp Reiser , Paul-Christian Bürkner , Anneli Guthke

In engineering design and scientific computing, computational cost and predictive accuracy are intrinsically coupled. High-fidelity simulations provide accurate predictions but at substantial computational costs, while lower-fidelity…

Machine Learning · Computer Science 2026-05-11 Ahmed Mohamed Eisa Nasr , Ali Elham , Haris Moazam Sheikh