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Related papers: Accelerating Scientific Discovery with Autonomous …

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Large language models (LLMs) have been shown to perform better when scaffolded into agents with memory, tools, and feedback. Beyond this, self-evolving agents have emerged, but current work largely limits adaptation to prompt rewriting or…

Artificial Intelligence · Computer Science 2025-10-28 Jiahao Qiu , Xuan Qi , Hongru Wang , Xinzhe Juan , Yimin Wang , Zelin Zhao , Jiayi Geng , Jiacheng Guo , Peihang Li , Jingzhe Shi , Shilong Liu , Mengdi Wang

Traditional optimization methods excel in well-defined search spaces but struggle with design problems where transformations and design parameters are difficult to define. Large language models (LLMs) offer a promising alternative by…

Machine Learning · Computer Science 2025-12-01 Anthony Carreon , Vansh Sharma , Venkat Raman

Progress in scientific discovery is rarely the result of a single "Eureka" moment, but is rather the product of hundreds of scientists incrementally working together toward a common goal. While existing agent workflows are capable of…

Artificial Intelligence · Computer Science 2025-03-25 Samuel Schmidgall , Michael Moor

Scientific data visualization plays a crucial role in research by enabling the direct display of complex information and assisting researchers in identifying implicit patterns. Despite its importance, the use of Large Language Models (LLMs)…

Computation and Language · Computer Science 2024-03-20 Zhiyu Yang , Zihan Zhou , Shuo Wang , Xin Cong , Xu Han , Yukun Yan , Zhenghao Liu , Zhixing Tan , Pengyuan Liu , Dong Yu , Zhiyuan Liu , Xiaodong Shi , Maosong Sun

Repurposing large vision-language models (LVLMs) as computer use agents (CUAs) has led to substantial breakthroughs, primarily driven by human-labeled data. However, these models often struggle with novel and specialized software,…

Artificial Intelligence · Computer Science 2025-08-13 Zeyi Sun , Ziyu Liu , Yuhang Zang , Yuhang Cao , Xiaoyi Dong , Tong Wu , Dahua Lin , Jiaqi Wang

Scientific discovery is a complex cognitive process that has driven human knowledge and technological progress for centuries. While artificial intelligence (AI) has made significant advances in automating aspects of scientific reasoning,…

Machine Learning · Computer Science 2024-12-24 Chandan K Reddy , Parshin Shojaee

Clinical trials are critical for advancing medical treatments but remain prohibitively expensive and time-consuming. Accurate prediction of clinical trial outcomes can significantly reduce research and development costs and accelerate drug…

Machine Learning · Computer Science 2025-06-06 Fengze Liu , Haoyu Wang , Joonhyuk Cho , Dan Roth , Andrew W. Lo

Autonomous scientific research is significantly advanced thanks to the development of AI agents. One key step in this process is finding the right scientific literature, whether to explore existing knowledge for a research problem, or to…

Intelligent personal assistants (IPAs) such as Siri and Google Assistant are designed to enhance human capabilities and perform tasks on behalf of users. The emergence of LLM agents brings new opportunities for the development of IPAs.…

Artificial Intelligence · Computer Science 2025-08-07 Chongyu Bao , Ruimin Dai , Yangbo Shen , Runyang Jian , Jinghan Zhang , Xiaolan Liu , Kunpeng Liu

The rapid expansion of scholarly publications across diverse disciplines has made it increasingly difficult to systematically evaluate how research contributes to the United Nations Sustainable Development Goals (SDGs). Domain…

Digital Libraries · Computer Science 2026-01-27 Sahil Dewani , Kiran Sharma

Mobile agents show immense potential, yet current state-of-the-art (SoTA) agents exhibit inadequate success rates on real-world, long-horizon, cross-application tasks. We attribute this bottleneck to the agents' excessive reliance on…

Artificial Intelligence · Computer Science 2026-03-13 Yuxiang Zhou , Jichang Li , Yanhao Zhang , Haonan Lu , Guanbin Li

Cognitive diagnosis plays a vital role in modern intelligent education platforms to reveal students' proficiency in knowledge concepts for subsequent adaptive tasks. However, due to the requirement of high model interpretability, existing…

Neural and Evolutionary Computing · Computer Science 2023-07-11 Shangshang Yang , Haiping Ma , Cheng Zhen , Ye Tian , Limiao Zhang , Yaochu Jin , Xingyi Zhang

To unleash the full potential of AI for Science, we must untether the agents from a purely digital environment. The agent's ability to control and explore in real-world labs is essential because the physical lab remains foundational to…

Systems and Control · Electrical Eng. & Systems 2026-05-19 Zhenning Yang , Yuhan Chen , Patrick Tser Jern Kon , Tongyuan Miao , Hongyi Lin , Venkat Viswanathan , Danai Koutra , Ang Chen

Designing autonomous driving systems requires efficient exploration of large hardware/software configuration spaces under diverse environmental conditions, e.g., with varying traffic, weather, and road layouts. Traditional design space…

Robotics · Computer Science 2025-12-10 Po-An Shih , Shao-Hua Wang , Yung-Che Li , Chia-Heng Tu , Chih-Han Chang

We present ScienceClaw + Infinite, a framework for autonomous scientific investigation in which independent agents conduct research without central coordination, and any contributor can deploy new agents into a shared ecosystem. The system…

Artificial Intelligence · Computer Science 2026-03-17 Fiona Y. Wang , Lee Marom , Subhadeep Pal , Rachel K. Luu , Wei Lu , Jaime A. Berkovich , Markus J. Buehler

Recent advances in large language models (LLMs) have shown great potential to accelerate drug discovery. However, the specialized nature of biochemical data often necessitates costly domain-specific fine-tuning, posing major challenges.…

Machine Learning · Computer Science 2025-11-17 Namkyeong Lee , Edward De Brouwer , Ehsan Hajiramezanali , Tommaso Biancalani , Chanyoung Park , Gabriele Scalia

Large language models (LLMs) have enabled powerful advances in natural language understanding and generation. Yet their application to complex, real-world scientific workflows remain limited by challenges in memory, planning, and tool…

Autonomous agents play a crucial role in advancing Artificial General Intelligence, enabling problem decomposition and tool orchestration through Large Language Models (LLMs). However, existing paradigms face a critical trade-off. On one…

Artificial Intelligence · Computer Science 2025-09-03 Jinzhou Tang , Jusheng Zhang , Qinhan Lv , Sidi Liu , Jing Yang , Chengpei Tang , Keze Wang

Automating scientific discovery in complex, experiment-driven domains requires more than iterative mutation of programs; it demands structured hypothesis management, environment interaction, and principled reflection. We present OR-Agent, a…

Artificial Intelligence · Computer Science 2026-02-26 Qi Liu , Ruochen Hao , Can Li , Wanjing Ma

Evolving one-dimensional cellular automata (CAs) with genetic algorithms has provided insight into how improved performance on a task requiring global coordination emerges when only local interactions are possible. Two approaches that can…

adap-org · Physics 2007-05-23 Justin Werfel , Melanie Mitchell , James P. Crutchfield