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Advances in robotic control and sensing have propelled the rise of automated scientific laboratories capable of high-throughput experiments. However, automated scientific laboratories are currently limited by human intuition in their…

Machine Learning · Computer Science 2024-12-18 Saaketh Desai , Sadhvikas Addamane , Jeffrey Y. Tsao , Igal Brener , Laura P. Swiler , Remi Dingreville , Prasad P. Iyer

Large language models (LLMs) can generate syntactically valid optimization programs, yet often struggle to reliably choose an effective modeling strategy, leading to incorrect formulations and inefficient solver behavior. We propose SAGE, a…

Artificial Intelligence · Computer Science 2026-05-05 Ruiqing Zhao , Fengzhi Li , Yuan Zuo , Rui Liu , Yansong Liu , Yunfei Ma , Fanyu Meng , Junlan Feng

Large language models (LLMs), have shown strong potential in scientific discovery, yet existing methods still face substantial challenges in the design of research workflows and multi-role collaboration mechanisms. To mitigate these issues,…

Artificial Intelligence · Computer Science 2026-05-26 Xiaoyu Xiong , Yuqi Ren , Deyi Xiong

Auxiliary objectives, supplementary learning signals that are introduced to help aid learning on data-starved or highly complex end-tasks, are commonplace in machine learning. Whilst much work has been done to formulate useful auxiliary…

Machine Learning · Computer Science 2023-03-01 Lucio M. Dery , Paul Michel , Mikhail Khodak , Graham Neubig , Ameet Talwalkar

The development of Large Language Models (LLMs) has catalyzed automation in customer service, yet benchmarking their performance remains challenging. Existing benchmarks predominantly rely on static paradigms and single-dimensional metrics,…

Artificial Intelligence · Computer Science 2026-04-13 Ling Shi , Yuqin Dai , Ziyin Wang , Ning Gao , Wei Zhang , Chaozheng Wang , Yujie Wang , Wei He , Jinpeng Wang , Deiyi Xiong

Long-term memory is becoming a central bottleneck for language agents. Exsting RAG and GraphRAG systems largely treat memory graphs as static retrieval middleware, which limits their ability to recover complete evidence chains from partial…

Artificial Intelligence · Computer Science 2026-05-13 Juntong Wang , Haoyue Zhao , guanghui Pan , Xiyuan Wang , Yanbo Wang , Qiyan Deng , Muhan Zhang

Inspired by cellular growth and self-organization, Neural Cellular Automata (NCAs) have been capable of "growing" artificial cells into images, 3D structures, and even functional machines. NCAs are flexible and robust computational systems…

Neural and Evolutionary Computing · Computer Science 2022-05-16 Shyam Sudhakaran , Elias Najarro , Sebastian Risi

With the rapid advancements in Large Language Models (LLMs), an increasing number of studies have leveraged LLMs as the cognitive core of agents to address complex task decision-making challenges. Specially, recent research has demonstrated…

Multiagent Systems · Computer Science 2025-03-13 Di Zhao , Longhui Ma , Siwei Wang , Miao Wang , Zhao Lv

Artificial Intelligence for Social Good (AI4SG) is an emerging effort that aims to address complex societal challenges with the powerful capabilities of AI systems. These challenges range from local issues with transit networks to global…

Artificial Intelligence · Computer Science 2025-04-29 Jacob Emmerson , Rayid Ghani , Zheyuan Ryan Shi

The advent of Large Language Models (LLMs) has created new opportunities for the automation of scientific research spanning both experimental processes and computational simulations. This study explores the feasibility of constructing an…

Artificial Intelligence · Computer Science 2025-01-16 Zhihan Liu , Yubo Chai , Jianfeng Li

Retrieval-Augmented Generation (RAG) enables large language models (LLMs) to access external knowledge sources, but the effectiveness of RAG relies on the coordination between the retriever and the generator. Since these components are…

Computation and Language · Computer Science 2025-09-24 Junlin Wang , Zehao Wu , Shaowei Lu , Yanlan Li , Xinghao Huang

Computer aided drug design is a promising approach to reduce the tremendous costs, i.e. time and resources, for developing new medicinal drugs. It finds application in aiding the traversal of the vast chemical space of potentially useful…

Neural and Evolutionary Computing · Computer Science 2024-05-02 Tomoya Hömberg , Sanaz Mostaghim , Satoru Hiwa , Tomoyuki Hiroyasu

Large Language Model (LLM)-based agents have recently shown impressive capabilities in complex reasoning and tool use via multi-step interactions with their environments. While these agents have the potential to tackle complicated tasks,…

Artificial Intelligence · Computer Science 2025-11-04 Jiaye Lin , Yifu Guo , Yuzhen Han , Sen Hu , Ziyi Ni , Licheng Wang , Mingguang Chen , Hongzhang Liu , Ronghao Chen , Yangfan He , Daxin Jiang , Binxing Jiao , Chen Hu , Huacan Wang

Creating end-to-end bioinformatics workflows requires diverse domain expertise, which poses challenges for both junior and senior researchers as it demands a deep understanding of both genomics concepts and computational techniques. While…

Artificial intelligence is reshaping scientific exploration, but most methods automate procedural tasks without engaging in scientific reasoning, limiting autonomy in discovery. We introduce Materials Agents for Simulation and Theory in…

Recent advances in agentic AI have enabled increasingly autonomous workflows, but existing systems still face substantial challenges in achieving reliable deployment in real-world scientific research. In this work, we present a safe,…

Artificial Intelligence · Computer Science 2026-04-16 Qibin Liu , Julia Gonski

Most commodity software lacks accessible Application Programming Interfaces (APIs), requiring autonomous agents to interact solely through pixel-based Graphical User Interfaces (GUIs). In this API-free setting, large language model…

Artificial Intelligence · Computer Science 2026-03-26 Chenwei Tang , Lin Long , Xinyu Liu , Jingyu Xing , Zizhou Wang , Joey Tianyi Zhou , Jiawei Du , Liangli Zhen , Jiancheng Lv

AI agents hold the potential to revolutionize scientific productivity by automating literature reviews, replicating experiments, analyzing data, and even proposing new directions of inquiry; indeed, there are now many such agents, ranging…

In this work, we present an extension of the genetic algorithm (GA) which exploits the supervised learning technique called active subspaces (AS) to evolve the individuals on a lower dimensional space. In many cases, GA requires in fact…

Numerical Analysis · Mathematics 2021-07-13 Nicola Demo , Marco Tezzele , Gianluigi Rozza

The rapid advancement of artificial intelligence (AI) has demonstrated substantial potential in chemical engineering, yet existing AI systems remain limited in interdisciplinary collaboration and exploration of uncharted problems. To…

Artificial Intelligence · Computer Science 2025-10-03 Zekun Jiang , Chunming Xu , Tianhang Zhou
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