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Vision-language models (VLMs) are increasingly adapted through domain-specific fine-tuning, yet it remains unclear whether this improves reasoning beyond superficial visual cues, particularly in high-stakes domains like medicine. We…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Oliver McLaughlin , Daniel Shubin , Carsten Eickhoff , Ritambhara Singh , William Rudman , Michal Golovanevsky

Despite the promise of foundation models in medical AI, current systems remain limited - they are modality-specific and lack transparent reasoning processes, hindering clinical adoption. To address this gap, we present EVLF-FM, a multimodal…

Puzzles have long served as compact and revealing probes of human cognition, isolating abstraction, rule discovery, and systematic reasoning with minimal reliance on prior knowledge. Leveraging these properties, visual puzzles have recently…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Maria Lymperaiou , Vasileios Karampinis , Giorgos Filandrianos , Angelos Vlachos , Chrysoula Zerva , Athanasios Voulodimos

Recent advancements indicate that scaling up Multimodal Large Language Models (MLLMs) effectively enhances performance on downstream multimodal tasks. The prevailing MLLM paradigm, \emph{e.g.}, LLaVA, transforms visual features into…

Artificial Intelligence · Computer Science 2024-03-21 Wenqiao Zhang , Tianwei Lin , Jiang Liu , Fangxun Shu , Haoyuan Li , Lei Zhang , He Wanggui , Hao Zhou , Zheqi Lv , Hao Jiang , Juncheng Li , Siliang Tang , Yueting Zhuang

Large Language Models (LLMs) are increasingly applied to medical imaging tasks, including image interpretation and synthetic image generation. However, these models often produce hallucinations, which are confident but incorrect outputs…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Anindya Bijoy Das , Shahnewaz Karim Sakib , Shibbir Ahmed

Multimodal Large Language Models (MLLMs) have become a powerful tool for integrating visual and textual information. Despite their exceptional performance on visual understanding benchmarks, measuring their ability to reason abstractly…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Nilay Yilmaz , Maitreya Patel , Yiran Lawrence Luo , Tejas Gokhale , Chitta Baral , Suren Jayasuriya , Yezhou Yang

Incentivizing the reasoning ability of Multimodal Large Language Models (MLLMs) is essential for medical applications to transparently analyze medical scans and provide reliable diagnosis. However, existing medical MLLMs rely solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Lehan Wang , Yi Qin , Honglong Yang , Xiaomeng Li

Multimodal Large Language Models (MLLMs) have shown remarkable capability in assisting disease diagnosis in medical visual question answering (VQA). However, their outputs remain vulnerable to hallucinations (i.e., responses that contradict…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Mengyuan Jin , Zehui Liao , Yong Xia

Large language models (LLMs) show promise in medical diagnosis, but real-world deployment remains challenging due to high-stakes clinical decisions and imperfect reasoning reliability. As a result, careful inspection of model behavior is…

Computation and Language · Computer Science 2026-04-28 Yurui Xiang , Xingyi Mao , Rui Sheng , Zixin Chen , Zelin Zang , Yuyang Wu , Haipeng Zeng , Huamin Qu , Yushi Sun , Yanna Lin

Large language models (LLMs) have shown remarkable ability in various language tasks, especially with their emergent in-context learning capability. Extending LLMs to incorporate visual inputs, large vision-language models (LVLMs) have…

Machine Learning · Computer Science 2025-10-13 Aneesh Komanduri , Karuna Bhaila , Xintao Wu

Vision-Language Models (VLMs) enable powerful multimodal reasoning but suffer from slow autoregressive inference, limiting their deployment in real-time applications. We introduce Spec-LLaVA, a system that applies speculative decoding to…

Computation and Language · Computer Science 2025-09-16 Mingxiao Huo , Jiayi Zhang , Hewei Wang , Jinfeng Xu , Zheyu Chen , Huilin Tai , Yijun Chen

Large language models (LLMs) have shown impressive performance on complex reasoning by leveraging chain-of-thought (CoT) prompting to generate intermediate reasoning chains as the rationale to infer the answer. However, existing CoT studies…

Computation and Language · Computer Science 2024-05-21 Zhuosheng Zhang , Aston Zhang , Mu Li , Hai Zhao , George Karypis , Alex Smola

Existing Large Vision-Language Models (LVLMs) excel at matching concepts across multi-modal inputs but struggle with compositional concepts and high-level relationships between entities. This paper introduces Progressive multi-granular…

Computer Vision and Pattern Recognition · Computer Science 2024-12-20 Quang-Hung Le , Long Hoang Dang , Ngan Le , Truyen Tran , Thao Minh Le

Interpretation is critical for disease diagnosis, but existing models struggle to balance predictive accuracy with human-understandable rationales. While large language models (LLMs) offer strong reasoning abilities, their clinical use is…

Computation and Language · Computer Science 2025-07-15 Shuai Niu , Jing Ma , Hongzhan Lin , Liang Bai , Zhihua Wang , Yida Xu , Yunya Song , Xian Yang

Large Vision Language Models (LVLMs) have recently achieved superior performance in various tasks on natural image and text data, which inspires a large amount of studies for LVLMs fine-tuning and training. Despite their advancements, there…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Zishan Gu , Changchang Yin , Fenglin Liu , Ping Zhang

Scientific research demands sophisticated reasoning over multimodal data, a challenge especially prevalent in biology. Despite recent advances in multimodal large language models (MLLMs) for AI-assisted research, existing multimodal…

Real-world clinical practice demands multi-image comparative reasoning, yet current medical benchmarks remain limited to single-frame interpretation. We present MedFrameQA, the first benchmark explicitly designed to test multi-image medical…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Suhao Yu , Haojin Wang , Juncheng Wu , Luyang Luo , Jingshen Wang , Cihang Xie , Pranav Rajpurkar , Carl Yang , Yang Yang , Kang Wang , Yannan Yu , Yuyin Zhou

Recent advancements in Vision-Language (VL) research have sparked new benchmarks for complex visual reasoning, challenging models' advanced reasoning ability. Traditional Vision-Language Models (VLMs) perform well in visual perception tasks…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Zhiyuan Li , Dongnan Liu , Chaoyi Zhang , Heng Wang , Tengfei Xue , Weidong Cai

With the rapid progress of large language models (LLMs), advanced multimodal large language models (MLLMs) have demonstrated impressive zero-shot capabilities on vision-language tasks. In the biomedical domain, however, even…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Siyuan Dai , Lunxiao Li , Kun Zhao , Eardi Lila , Paul K. Crane , Heng Huang , Dongkuan Xu , Haoteng Tang , Liang Zhan

The differential diagnosis of neurodegenerative dementias is a challenging clinical task, mainly because of the overlap in symptom presentation and the similarity of patterns observed in structural neuroimaging. To improve diagnostic…

Machine Learning · Computer Science 2025-05-27 Andrew Zamai , Nathanael Fijalkow , Boris Mansencal , Laurent Simon , Eloi Navet , Pierrick Coupe