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High-fidelity generative models are increasingly needed in privacy-sensitive scenarios, where access to data is severely restricted due to regulatory and copyright constraints. This scarcity hampers model development--ironically, in…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Xuemei Jia , Jiawei Du , Hui Wei , Jun Chen , Joey Tianyi Zhou , Zheng Wang

As Deep Learning algorithms continue to evolve and become more sophisticated, they require massive datasets for model training and efficacy of models. Some of those data requirements can be met with the help of existing datasets within the…

Machine Learning · Statistics 2022-04-07 Monik Raj Behera , Sudhir Upadhyay , Suresh Shetty , Sudha Priyadarshini , Palka Patel , Ker Farn Lee

Each year, hundreds of clinical trials are conducted to evaluate new medical interventions, but sharing patient records from these trials with other institutions can be challenging due to privacy concerns and federal regulations. To help…

Machine Learning · Computer Science 2025-02-19 Trisha Das , Zifeng Wang , Afrah Shafquat , Mandis Beigi , Jason Mezey , Jacob Aptekar , Jimeng Sun

Synthetic data generation is an important application of machine learning in the field of medical imaging. While existing approaches have successfully applied fine-tuned diffusion models for synthesizing medical images, we explore potential…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Lakshmi Nair

Artificial intelligence (AI) is increasingly used in every stage of drug development. Continuing breakthroughs in AI-based methods for drug discovery require the creation, improvement, and refinement of drug discovery data. We posit a new…

Machine Learning · Computer Science 2024-05-08 Bing Hu , Ashish Saragadam , Anita Layton , Helen Chen

Artificial Intelligence and digital health have the potential to transform global health. However, having access to representative data to test and validate algorithms in realistic production environments is essential. We introduce…

Recent years have witnessed a surge in the popularity of Machine Learning (ML), applied across diverse domains. However, progress is impeded by the scarcity of training data due to expensive acquisition and privacy legislation. Synthetic…

Machine Learning · Computer Science 2024-02-05 André Bauer , Simon Trapp , Michael Stenger , Robert Leppich , Samuel Kounev , Mark Leznik , Kyle Chard , Ian Foster

Synthetic Data Generation (SDG), leveraging Large Language Models (LLMs), has recently been recognized and broadly adopted as an effective approach to improve the performance of smaller but more resource and compute efficient LLMs through…

Machine Learning · Computer Science 2026-03-25 Srideepika Jayaraman , Achille Fokoue , Dhaval Patel , Jayant Kalagnanam

Sensitive medical data is often subject to strict usage constraints. In this paper, we trained a generative adversarial network (GAN) on real-world electronic health records (EHR). It was then used to create a data-set of "fake" patients…

Machine Learning · Computer Science 2021-09-07 John Weldon , Tomas Ward , Eoin Brophy

In this paper, we propose a data privacy-preserving and communication efficient distributed GAN learning framework named Distributed Asynchronized Discriminator GAN (AsynDGAN). Our proposed framework aims to train a central generator learns…

Image and Video Processing · Electrical Eng. & Systems 2020-06-16 Qi Chang , Hui Qu , Yikai Zhang , Mert Sabuncu , Chao Chen , Tong Zhang , Dimitris Metaxas

Deep learning algorithms require extensive data to achieve robust performance. However, data availability is often restricted in the medical domain due to patient privacy concerns. Synthetic data presents a possible solution to these…

Single Domain Generalization (SDG) aims to train models that maintain consistent performance across diverse scenarios using data from a single source. While latent diffusion models (LDMs) show promise for augmenting limited source data, our…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Hao Li , Yubin Xiao , Ke Liang , Mengzhu Wang , Long Lan , Kenli Li , Xinwang Liu

Swarm learning (SL) is an emerging promising decentralized machine learning paradigm and has achieved high performance in clinical applications. SL solves the problem of a central structure in federated learning by combining edge computing…

Machine Learning · Computer Science 2022-12-05 Zirui Wang , Shaoming Duan , Chengyue Wu , Wenhao Lin , Xinyu Zha , Peiyi Han , Chuanyi Liu

The limited data availability due to strict privacy regulations and significant resource demands severely constrains biomedical time-series AI development, which creates a critical gap between data requirements and accessibility. Synthetic…

Machine Learning · Computer Science 2025-11-25 Youngjoon Lee , Seongmin Cho , Yehhyun Jo , Jinu Gong , Hyunjoo Jenny Lee , Joonhyuk Kang

Sensitive datasets are often underutilized in research and industry due to privacy concerns, limiting the potential of valuable data-driven insights. Synthetic data generation presents a promising solution to address this challenge by…

Computation · Statistics 2026-01-27 Ali Furkan Kalay

Deep learning models have demonstrated superior performance in several application problems, such as image classification and speech processing. However, creating a deep learning model using health record data requires addressing certain…

Machine Learning · Computer Science 2021-12-14 Amirsina Torfi , Edward A. Fox , Chandan K. Reddy

Preservation of private user data is of paramount importance for high Quality of Experience (QoE) and acceptability, particularly with services treating sensitive data, such as IT-based health services. Whereas anonymization techniques were…

Machine Learning · Computer Science 2024-03-04 Navid Ashrafi , Vera Schmitt , Robert P. Spang , Sebastian Möller , Jan-Niklas Voigt-Antons

The increasing reliance on large-scale datasets in machine learning poses significant privacy and ethical challenges, particularly in sensitive domains such as face recognition. Synthetic data generation offers a promising alternative;…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Parsa Rahimi , Damien Teney , Sebastien Marcel

Synthetic data generation offers a promising solution to enhance the usefulness of Electronic Healthcare Records (EHR) by generating realistic de-identified data. However, the existing literature primarily focuses on the quality of…

Machine Learning · Computer Science 2024-04-29 Resmi Ramachandranpillai , Md Fahim Sikder , David Bergström , Fredrik Heintz

Utility and privacy are two crucial measurements of the quality of synthetic tabular data. While significant advancements have been made in privacy measures, generating synthetic samples with high utility remains challenging. To enhance the…

Machine Learning · Computer Science 2024-03-28 Oriel Perets , Nadav Rappoport
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