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Acquiring large quantities of data and annotations is known to be effective for developing high-performing deep learning models, but is difficult and expensive to do in the healthcare context. Adding synthetic training data using generative…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Menghan Yu , Sourabh Kulhare , Courosh Mehanian , Charles B Delahunt , Daniel E Shea , Zohreh Laverriere , Ishan Shah , Matthew P Horning

Recent advances in synthetic data generation (SDG) have been hailed as a solution to the difficult problem of sharing sensitive data while protecting privacy. SDG aims to learn statistical properties of real data in order to generate…

Machine Learning · Computer Science 2024-05-10 Meenatchi Sundaram Muthu Selva Annamalai , Andrea Gadotti , Luc Rocher

Retrieval-Augmented Generation (RAG) has attracted significant attention due to its ability to combine the generative capabilities of Large Language Models (LLMs) with knowledge obtained through efficient retrieval mechanisms over…

Cryptography and Security · Computer Science 2026-01-19 Aiman Al Masoud , Marco Arazzi , Antonino Nocera

The recent availability of electronic health records (EHRs) have provided enormous opportunities to develop artificial intelligence (AI) algorithms. However, patient privacy has become a major concern that limits data sharing across…

Machine Learning · Computer Science 2023-02-01 Jin Li , Benjamin J. Cairns , Jingsong Li , Tingting Zhu

Privacy concerns around sharing personally identifiable information are a major practical barrier to data sharing in medical research. However, in many cases, researchers have no interest in a particular individual's information but rather…

Image and Video Processing · Electrical Eng. & Systems 2021-08-18 August DuMont Schütte , Jürgen Hetzel , Sergios Gatidis , Tobias Hepp , Benedikt Dietz , Stefan Bauer , Patrick Schwab

Problem: There is a lack of big data for the training of deep learning models in medicine, characterized by the time cost of data collection and privacy concerns. Generative adversarial networks (GANs) offer both the potential to generate…

Image and Video Processing · Electrical Eng. & Systems 2022-05-09 Ethan Schonfeld , Anand Veeravagu

The usage of medical image data for the training of large-scale machine learning approaches is particularly challenging due to its scarce availability and the costly generation of data annotations, typically requiring the engagement of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-26 Joshua Niemeijer , Jan Ehrhardt , Hristina Uzunova , Heinz Handels

In recent years, the machine learning research community has benefited tremendously from the availability of openly accessible benchmark datasets. Clinical data are usually not openly available due to their highly confidential nature. This…

Translational brain research using Magnetic Resonance Imaging (MRI) is becoming increasingly popular as animal models are an essential part of scientific studies and more ultra-high-field scanners are becoming available. Some disadvantages…

Image and Video Processing · Electrical Eng. & Systems 2022-01-05 André Ferreira , Ricardo Magalhães , Sébastien Mériaux , Victor Alves

Synthetic data generation has emerged as a promising approach to address the challenges of using sensitive financial data in machine learning applications. By leveraging generative models, such as Generative Adversarial Networks (GANs) and…

Machine Learning · Computer Science 2025-10-31 James Meldrum , Basem Suleiman , Fethi Rabhi , Muhammad Johan Alibasa

Generative artificial intelligence has transformed the generation of synthetic data, providing innovative solutions to challenges like data scarcity and privacy, which are particularly critical in fields such as medicine. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-31 Eugenio Lomurno , Matteo Matteucci

Face recognition models are trained on large-scale datasets, which have privacy and ethical concerns. Lately, the use of synthetic data to complement or replace genuine data for the training of face recognition models has been proposed.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 David Geissbühler , Hatef Otroshi Shahreza , Sébastien Marcel

Generative adversarial networks (GANs) have attracted intense interest in the field of generative models. However, few investigations focusing either on the theoretical analysis or on algorithm design for the approximation ability of the…

Machine Learning · Computer Science 2020-07-14 Xuejiao Liu , Yao Xu , Xueshuang Xiang

The widespread adoption of electronic health records and digital healthcare data has created a demand for data-driven insights to enhance patient outcomes, diagnostics, and treatments. However, using real patient data presents privacy and…

Machine Learning · Computer Science 2023-11-15 Aryan Jadon , Shashank Kumar

Programmatically generated synthetic data has been used in differential private training for classification to enhance performance without privacy leakage. However, as the synthetic data is generated from a random process, the distribution…

Machine Learning · Computer Science 2024-12-16 Yujin Choi , Jinseong Park , Junyoung Byun , Jaewook Lee

Tabular data sharing under privacy constraints is increasingly important for research and collaboration. Synthetic data generators (SDGs) are a promising solution, but synthetic data remains vulnerable to attacks, such as membership…

Machine Learning · Computer Science 2026-05-15 Davide Scassola , Andrea Coser , Sebastiano Saccani

Imbalanced data are commonly present in real-world applications. While data synthesis can effectively mitigate data scarcity for rare classes, and LLMs have revolutionized text generation, the application of LLMs to the synthesis of…

Synthetic data generation, a cornerstone of Generative Artificial Intelligence, promotes a paradigm shift in data science by addressing data scarcity and privacy while enabling unprecedented performance. As synthetic data becomes more…

Machine Learning · Statistics 2024-03-12 Xiaotong Shen , Yifei Liu , Rex Shen

Large language models (LLMs) achieve strong downstream performance largely due to abundant supervised fine-tuning (SFT) data. However, high-quality SFT data in knowledge-intensive domains such as humanities, social sciences, medicine, law,…

Computation and Language · Computer Science 2026-04-02 Zhiting Fan , Ruizhe Chen , Tianxiang Hu , Ru Peng , Zenan Huang , Haokai Xu , Yixin Chen , Jian Wu , Junbo Zhao , Zuozhu Liu

Clinical data usually cannot be freely distributed due to their highly confidential nature and this hampers the development of machine learning in the healthcare domain. One way to mitigate this problem is by generating realistic synthetic…