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Whole slide images are the foundation of digital pathology for the diagnosis and treatment of carcinomas. Writing pathology reports is laborious and error-prone for inexperienced pathologists. To reduce the workload and improve clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Pingyi Chen , Honglin Li , Chenglu Zhu , Sunyi Zheng , Zhongyi Shui , Lin Yang

Image tiling -- the seamless connection of disparate images to create a coherent visual field -- is crucial for applications such as texture creation, video game asset development, and digital art. Traditionally, tiles have been constructed…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Or Madar , Ohad Fried

Background: The integration of multi-stain histopathology images through deep learning poses a significant challenge in digital histopathology. Current multi-modal approaches struggle with data heterogeneity and missing data. This study…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Valentin Koch , Sabine Bauer , Valerio Luppberger , Michael Joner , Heribert Schunkert , Julia A. Schnabel , Moritz von Scheidt , Carsten Marr

Multimodal survival methods combining gigapixel histology whole-slide images (WSIs) and transcriptomic profiles are particularly promising for patient prognostication and stratification. Current approaches involve tokenizing the WSIs into…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Andrew H. Song , Richard J. Chen , Guillaume Jaume , Anurag J. Vaidya , Alexander S. Baras , Faisal Mahmood

Vision Transformer models process input images by dividing them into a spatially regular grid of equal-size patches. Conversely, Transformers were originally introduced over natural language sequences, where each token represents a subword…

Computer Vision and Pattern Recognition · Computer Science 2023-04-28 Tomer Ronen , Omer Levy , Avram Golbert

In pathological research, education, and clinical practice, the decision-making process based on pathological images is critically important. This significance extends to digital pathology image analysis: its adequacy is demonstrated by the…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Zhi-Bo Liu , Xiaobo Pang , Jizhao Wang , Shuai Liu , Chen Li

The field of digital pathology has seen a proliferation of deep learning models in recent years. Despite substantial progress, it remains rare for other researchers and pathologists to be able to access models published in the literature…

Tissues and Organs · Quantitative Biology 2024-01-15 Jakub R. Kaczmarzyk , Alan O'Callaghan , Fiona Inglis , Tahsin Kurc , Rajarsi Gupta , Erich Bremer , Peter Bankhead , Joel H. Saltz

Transformers predict over a representation of a sequence. The same data can be written as bytes, characters, or subword tokens, and these representations may be lossless. Yet, under a fixed context window, they need not expose the same…

Machine Learning · Computer Science 2026-05-14 Amirmehdi Jafari Fesharaki , Mohammadamin Rami , Aslan Tchamkerten

Whole slide image (WSI) assessment is a challenging and crucial step in cancer diagnosis and treatment planning. WSIs require high magnifications to facilitate sub-cellular analysis. Precise annotations for patch- or even pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Simon Holdenried-Krafft , Peter Somers , Ivonne A. Montes-Majarro , Diana Silimon , Cristina Tarín , Falko Fend , Hendrik P. A. Lensch

Advances in foundation modeling have reshaped computational pathology. However, the increasing number of available models and lack of standardized benchmarks make it increasingly complex to assess their strengths, limitations, and potential…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Andrew Zhang , Guillaume Jaume , Anurag Vaidya , Tong Ding , Faisal Mahmood

Generating diagnostic text from histopathology whole slide images (WSIs) is challenging due to the gigapixel scale of the input and the requirement for precise, domain specific language. We propose a hierarchical vision language framework…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Ahmet Halici , Ece Tugba Cebeci , Musa Balci , Mustafa Cini , Serkan Sokmen

Multiple instance learning (MIL) is the preferred approach for whole slide image classification. However, most MIL approaches do not exploit the interdependencies of tiles extracted from a whole slide image, which could provide valuable…

Computer Vision and Pattern Recognition · Computer Science 2021-08-26 Marvin Lerousseau , Maria Vakalopoulou , Eric Deutsch , Nikos Paragios

Vision Transformers are at the heart of the current surge of interest in foundation models for histopathology. They process images by breaking them into smaller patches following a regular grid, regardless of their content. Yet, not all…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Clément Grisi , Geert Litjens , Jeroen van der Laak

The expanding ecosystem of pathology foundation models has produced powerful but fragmented tile-level representations, limiting their use in clinical tasks that require unified slide-level reasoning and interpretable linkage to clinically…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Tianyang Wang , Ziyu Su , Abdul Rehman Akbar , Usama Sajjad , Lina Gokhale , Charles Rabolli , Wei Chen , Anil Parwani , Muhammad Khalid Khan Niazi

Recent advances in whole-slide image (WSI) scanners and computational capabilities have significantly propelled the application of artificial intelligence in histopathology slide analysis. While these strides are promising, current…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Weiyi Wu , Chongyang Gao , Joseph DiPalma , Soroush Vosoughi , Saeed Hassanpour

Masked Image Modeling (MIM) achieves outstanding success in self-supervised representation learning. Unfortunately, MIM models typically have huge computational burden and slow learning process, which is an inevitable obstacle for their…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Haoqing Wang , Yehui Tang , Yunhe Wang , Jianyuan Guo , Zhi-Hong Deng , Kai Han

Multi-modal learning adeptly integrates visual and textual data, but its application to histopathology image and text analysis remains challenging, particularly with large, high-resolution images like gigapixel Whole Slide Images (WSIs).…

Computer Vision and Pattern Recognition · Computer Science 2024-05-29 Quan Liu , Ruining Deng , Can Cui , Tianyuan Yao , Vishwesh Nath , Yucheng Tang , Yuankai Huo

Regions of Interest (ROI) contain morphological features in pathology whole slide images (WSI) are delimited with polygons[1]. These polygons are often represented in either a textual notation (with the array of edges) or in a binary mask…

Graphics · Computer Science 2020-05-15 Erich Bremer , Jonas Almeida , Joel Saltz

Computational pathology relies on effective representation learning to support cancer research and precision medicine. Although self-supervised learning has driven major progress at the patch and whole-slide image levels, representation…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Loïc Chadoutaud , Alice Blondel , Hana Feki , Jacqueline Fontugne , Emmanuel Barillot , Thomas Walter

Attributed network embedding aims to learn low-dimensional vector representations for nodes in a network, where each node contains rich attributes/features describing node content. Because network topology structure and node attributes…

Social and Information Networks · Computer Science 2018-10-17 Daokun Zhang , Jie Yin , Xingquan Zhu , Chengqi Zhang