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Compartmentalization of biochemical processes underlies all biological systems, from the organelle to the tissue scale. Theoretical models to study the interplay between noisy reaction dynamics and compartmentalization are sparse, and…

Quantitative Methods · Quantitative Biology 2022-06-08 Lorenzo Duso , Christoph Zechner

In the context of uncertainty quantification, computational models are required to be repeatedly evaluated. This task is intractable for costly numerical models. Such a problem turns out to be even more severe for stochastic simulators, the…

Computation · Statistics 2022-11-29 X. Zhu , B. Sudret

We introduce a language for formally reasoning about programs that combine differential constructs with probabilistic ones. The language harbours, for example, such systems as adaptive cruise controllers, continuous-time random walks, and…

Logic in Computer Science · Computer Science 2025-07-23 Renato Neves , José Proença , Juliana Souza

Stochastic orders are very useful tool to compare the lifetimes of two coherent systems. We show that, under certain conditions, a coherent system of used components performs better (worse) than a used coherent system with respect to…

Applications · Statistics 2016-01-20 Nil Kamal Hazra , Asok K. Nanda

The problem of learning a computational model from examples has been receiving growing attention. For the particularly challenging problem of learning models of distributed systems, existing results are restricted to models with a fixed…

Formal Languages and Automata Theory · Computer Science 2023-12-13 Dana Fisman , Noa Izsak , Swen Jacobs

Statistical thermodynamics delivers the probability distribution of the equilibrium state of matter through the constrained maximization of a special functional, entropy. Its elegance and enormous success have led to numerous attempts to…

Statistical Mechanics · Physics 2023-06-22 Themis Matsoukas

The study of density-dependent stochastic population processes is important from a historical perspective as well as from the perspective of a number of existing and emerging applications today. In more recent applications of these…

Optimization and Control · Mathematics 2017-09-26 Yingdong Lu , Mark Squillante , Chai Wah Wu

Systems with stochastic time delay between the input and output present a number of unique challenges. Time domain noise leads to irregular alignments, obfuscates relationships and attenuates inferred coefficients. To handle these…

Methodology · Statistics 2021-11-15 Juan Camilo Orduz , Aaron Pickering

Stochastic systems feature, in general, both coherent dynamics and incoherent transitions between different states. We propose a method to identify the coherent part in the full counting statistics for the transitions. The proposal is…

Mesoscale and Nanoscale Physics · Physics 2018-07-10 Philipp Stegmann , Jürgen König , Stephan Weiss

We study general stochastic birth and death processes including delay. We develop several approaches for the analytical treatment of these non-Markovian systems, valid, not only for constant delays, but also for stochastic delays with…

Statistical Mechanics · Physics 2015-06-11 Luis F. Lafuerza , Raul Toral

The modelling and analysis of biological systems has deep roots in Mathematics, specifically in the field of ordinary differential equations (ODEs). Alternative approaches based on formal calculi, often derived from process algebras or term…

Programming Languages · Computer Science 2010-11-03 Mario Coppo , Ferruccio Damiani , Maurizio Drocco , Elena Grassi , Eva Sciacca , Salvatore Spinella , Angelo Troina

The latent stochastic block model is a flexible and widely used statistical model for the analysis of network data. Extensions of this model to a dynamic context often fail to capture the persistence of edges in contiguous network…

Methodology · Statistics 2018-04-16 Riccardo Rastelli

Population protocols are a distributed computing model appropriate for describing massive numbers of agents with limited computational power. A population protocol "has an initial leader" if every valid initial configuration contains a…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-11-06 Amanda Belleville , David Doty , David Soloveichik

We consider the problem of online scheduling on a single machine in order to minimize weighted flow time. The existing algorithms for this problem (STOC '01, SODA '03, FOCS '18) all require exact knowledge of the processing time of each…

Data Structures and Algorithms · Computer Science 2021-03-10 Yossi Azar , Stefano Leonardi , Noam Touitou

Hybrid systems whose mode dynamics are governed by non-linear ordinary differential equations (ODEs) are often a natural model for biological processes. However such models are difficult to analyze. To address this, we develop a…

Systems and Control · Computer Science 2015-06-23 Benjamin M. Gyori , Bing Liu , Soumya Paul , R. Ramanathan , P. S. Thiagarajan

Modelling complex information systems often entails the need for dealing with scenarios of inconsistency in which several requirements either reinforce or contradict each other. In this kind of scenarios, arising e.g. in knowledge…

Logic in Computer Science · Computer Science 2022-04-15 Ana Cruz , Alexandre Madeira , Luís Soares Barbosa

We introduce a variant of transition systems, where activation of transitions depends on conditions of the environment and upgrades during runtime potentially create additional transitions. Using a cornerstone result in lattice theory, we…

Software Engineering · Computer Science 2017-06-09 Harsh Beohar , Barbara König , Sebastian Küpper , Alexandra Silva

Designing distributed systems to have predictable performance under high load is difficult because of resource exhaustion, non-linearity, and stochastic behaviour. Timeliness, i.e., delivering results within defined time bounds, is a…

Population protocols are a model of distributed computing where $n$ agents, each a simple finite-state machine, interact in pairs to solve a common task against a (adversarial) interaction scheduler. This model was intensively studied in…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-19 Tom-Lukas Breitkopf , Julien Dallot , Antoine El-Hayek , Stefan Schmid

It has recently been shown that structural conditions on the reaction network, rather than a 'fine-tuning' of system parameters, often suffice to impart 'absolute concentration robustness' on a wide class of biologically relevant,…

Probability · Mathematics 2014-01-20 David F. Anderson , German Enciso , Matthew Johnston
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