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The structure of grey matter has long been a key focus in neuroscience, as cell morphology varies by type and can be affected by neurological conditions. Understanding these variations is essential for studying brain function and disease.…

Biological Physics · Physics 2025-08-27 Charlie Aird-Rossiter , Hui Zhang , Daniel C. Alexander , Derek K. Jones , Marco Palombo

Medicine is inherently a multimodal discipline. Medical images can reflect the pathological changes of cancer and tumors, while the expression of specific genes can influence their morphological characteristics. However, most deep learning…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Jiaying Zhou , Mingzhou Jiang , Junde Wu , Jiayuan Zhu , Ziyue Wang , Yueming Jin

Imaging in clinical routine is subject to changing scanner protocols, hardware, or policies in a typically heterogeneous set of acquisition hardware. Accuracy and reliability of deep learning models suffer from those changes as data and…

Machine Learning · Computer Science 2021-06-08 Matthias Perkonigg , Johannes Hofmanninger , Georg Langs

Semiconductor imaging and analysis are critical yet understudied in deep learning, limiting our ability for precise control and optimization in semiconductor manufacturing. We introduce a small-scale multimodal framework for analyzing…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Sakhinana Sagar Srinivas , Chidaksh Ravuru , Geethan Sannidhi , Venkataramana Runkana

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

Multimodal magnetic resonance imaging (MRI) constitutes the first line of investigation for clinicians in the care of brain tumors, providing crucial insights for surgery planning, treatment monitoring, and biomarker identification.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Lucas Robinet , Ahmad Berjaoui , Elizabeth Cohen-Jonathan Moyal

Representation learning has driven major advances in natural image analysis by enabling models to acquire high-level semantic features. In microscopy imaging, however, it remains unclear what current representation learning methods actually…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Ivan Svatko , Maxime Sanchez , Ihab Bendidi , Gilles Cottrell , Auguste Genovesio

With the growth of artificial intelligence (AI), there has been an increase in the adoption of computer vision and deep learning (DL) techniques for the evaluation of microscopy images and movies. This adoption has not only addressed…

Quantitative Methods · Quantitative Biology 2023-07-21 Binghao Chai , Christoforos Efstathiou , Haoran Yue , Viji M. Draviam

Vision Transformers (ViTs) have achieved remarkable success in standard RGB image processing tasks. However, applying ViTs to multi-channel imaging (MCI) data, e.g., for medical and remote sensing applications, remains a challenge. In…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Wenyi Lian , Patrick Micke , Joakim Lindblad , Nataša Sladoje

Image-based profiling techniques have become increasingly popular over the past decade for their applications in target identification, mechanism-of-action inference, and assay development. These techniques have generated large datasets of…

Biomolecules · Quantitative Biology 2023-06-28 Cuong Q. Nguyen , Dante Pertusi , Kim M. Branson

The current cancer treatment practice collects multimodal data, such as radiology images, histopathology slides, genomics and clinical data. The importance of these data sources taken individually has fostered the recent raise of radiomics…

Machine Learning · Computer Science 2023-06-16 Matteo Tortora , Ermanno Cordelli , Rosa Sicilia , Lorenzo Nibid , Edy Ippolito , Giuseppe Perrone , Sara Ramella , Paolo Soda

The medical image analysis field has traditionally been focused on the development of organ-, and disease-specific methods. Recently, the interest in the development of more 20 comprehensive computational anatomical models has grown,…

Computer Vision and Pattern Recognition · Computer Science 2018-12-21 Juan J. Cerrolaza , Mirella Lopez-Picazo , Ludovic Humbert , Yoshinobu Sato , Daniel Rueckert , Miguel Angel Gonzalez Ballester , Marius George Linguraru

Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…

Image and Video Processing · Electrical Eng. & Systems 2022-09-30 Puria Azadi Moghadam , Sanne Van Dalen , Karina C. Martin , Jochen Lennerz , Stephen Yip , Hossein Farahani , Ali Bashashati

How morphogenesis depends on cell properties is an active direction of research. Here, we focus on mechanical models of growing plant tissues, where microscopic (sub)cellular structure is taken into account. In order to establish links…

Analysis of PDEs · Mathematics 2023-11-21 Arezki Boudaoud , Annamaria Kiss , Mariya Ptashnyk

Microscopy images contain rich information about how cells respond to perturbations, making them essential to applications like drug screening. To quantify images, researchers often use representation extraction methods, and recent years…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Emre Hayir , Lorin Crawford , Alex X. Lu

Model-driven analysis of biophysical phenomena is gaining increased attention and utility for medical imaging applications. In magnetic resonance imaging (MRI), the availability of well-established models for describing the relations…

Medical Physics · Physics 2023-10-31 Dinor Nagar , Nikita Vladimirov , Christian T. Farrar , Or Perlman

Extracting table contents from documents such as scientific papers and financial reports and converting them into a format that can be processed by large language models is an important task in knowledge information processing. End-to-end…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Takaya Kawakatsu

Understanding the mechanisms of interactions within cells, tissues, and organisms is crucial to driving developments across biology and medicine. Mathematical modeling is an essential tool for simulating biological systems and revealing…

Molecular Networks · Quantitative Biology 2024-08-13 Lingxia Qiao , Ali Khalilimeybodi , Nathaniel J Linden-Santangeli , Padmini Rangamani

The phase field model can accurately simulate the evolution of microstructures with complex morphologies, and it has been widely used for cell modeling in the last two decades. However, compared to other cellular models such as the…

Biological Physics · Physics 2022-06-13 Xiangyu Kuang , Guoye Guan , Chao Tang , Lei Zhang

Prior work using Masked Autoencoders (MAEs) typically relies on random patch masking based on the assumption that images have significant redundancies across different channels, allowing for the reconstruction of masked content using…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Chau Pham , Juan C. Caicedo , Bryan A. Plummer