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Therapeutic decision-making in clinical medicine constitutes a high-stakes domain in which AI guidance interacts with complex interactions among patient characteristics, disease processes, and pharmacological agents. Tasks such as drug…

Artificial Intelligence · Computer Science 2025-12-15 Tim Cofala , Christian Kalfar , Jingge Xiao , Johanna Schrader , Michelle Tang , Wolfgang Nejdl

Large Reasoning Models (LRMs) represent a breakthrough in AI problem-solving capabilities, but their effectiveness in interactive environments can be limited. This paper introduces and analyzes overthinking in LRMs. A phenomenon where…

Equipping large language models (LLMs) with complex, interleaved reasoning and tool-use capabilities has become a key focus in agentic AI research, especially with recent advances in reasoning-oriented (``thinking'') models. Such…

Artificial Intelligence · Computer Science 2025-09-10 Xuan-Phi Nguyen , Shrey Pandit , Revanth Gangi Reddy , Austin Xu , Silvio Savarese , Caiming Xiong , Shafiq Joty

Large Reasoning Models (LRMs) exhibit human-like cognitive reasoning strategies (e.g. backtracking, cross-verification) during reasoning process, which improves their performance on complex tasks. Currently, reasoning strategies are…

Artificial Intelligence · Computer Science 2026-01-08 Yi Fang , Wenjie Wang , Mingfeng Xue , Boyi Deng , Fengli Xu , Dayiheng Liu , Fuli Feng

Large Language Model (LLM)-powered Multi-agent systems (MAS) have achieved state-of-the-art results on various complex reasoning tasks. Recent works have proposed techniques to automate the design of MASes, eliminating the need for manual…

Artificial Intelligence · Computer Science 2026-05-20 Bohan Yao , Shiva Krishna Reddy Malay , Vikas Yadav

Large Language Model (LLM)-based agents have recently shown impressive capabilities in complex reasoning and tool use via multi-step interactions with their environments. While these agents have the potential to tackle complicated tasks,…

Artificial Intelligence · Computer Science 2025-11-04 Jiaye Lin , Yifu Guo , Yuzhen Han , Sen Hu , Ziyi Ni , Licheng Wang , Mingguang Chen , Hongzhang Liu , Ronghao Chen , Yangfan He , Daxin Jiang , Binxing Jiao , Chen Hu , Huacan Wang

The application of Large Language Models (LLMs) in recommender systems faces key challenges in delivering deep personalization and intelligent reasoning, especially for interactive scenarios. Current methods are often constrained by limited…

Information Retrieval · Computer Science 2025-10-17 Jiani Huang , Xingchen Zou , Lianghao Xia , Qing Li

While modern recommender systems are instrumental in navigating information abundance, they remain fundamentally limited by static user modeling and reactive decision-making paradigms. Current large language model (LLM)-based agents inherit…

Artificial Intelligence · Computer Science 2025-08-27 Chenghao Wu , Ruiyang Ren , Junjie Zhang , Ruirui Wang , Zhongrui Ma , Qi Ye , Wayne Xin Zhao

The rapid adoption of large language models (LLMs) in digital health has been driven by a "scaling-first" philosophy, i.e., the assumption that clinical intelligence increases with model size and data. However, real-world clinical needs…

Artificial Intelligence · Computer Science 2026-05-29 Yuqiao Meng , Luoxi Tang , Dazheng Zhang , Rafael Brens , Elvys J. Romero , Nancy Guo , Safa Elkefi , Zhaohan Xi

Large Language Models (LLMs) have demonstrated powerful reasoning capabilities through Chain-of-Thought (CoT) in various tasks, yet the inefficiency of token-by-token generation hinders real-world deployment in latency-sensitive recommender…

Information Retrieval · Computer Science 2026-05-12 Yiwen Chen , Fuwei Zhang , Zehao Chen , Deqing Wang , Hehan Li , Peizhi Xu , Hanmeng Liu , Shuanglong Li , Xin Pei , Fuzhen Zhuang , Zhao Zhang

Single-agent systems (SAS) have become the default pattern for LLM-driven scientific workflows, but routing planning, tool use, and synthesis through a single context window comes with a well-known cost: as tool specifications and…

Artificial Intelligence · Computer Science 2026-05-05 Jinpai Zhao , Albert Cerrone , Joannes Westerink , Clint Dawson

We present Tell Me, a mental well-being system that leverages advances in large language models to provide accessible, context-aware support for users and researchers. The system integrates three components: (i) a retrieval-augmented…

Computation and Language · Computer Science 2025-11-19 Trishala Jayesh Ahalpara

Sequential recommendation aims to predict a user's next action in large-scale recommender systems. While traditional methods often suffer from insufficient information interaction, recent generative recommendation models partially address…

Information Retrieval · Computer Science 2026-02-10 Haibo Xing , Hao Deng , Yucheng Mao , Lingyu Mu , Jinxin Hu , Yi Xu , Hao Zhang , Jiahao Wang , Shizhun Wang , Yu Zhang , Xiaoyi Zeng , Jing Zhang

Clinical decision-making in radiology increasingly benefits from artificial intelligence (AI), particularly through large language models (LLMs). However, traditional retrieval-augmented generation (RAG) systems for radiology question…

We introduce Synthetic Alignment data Generation for Safety Evaluation and Red Teaming (SAGE-RT or SAGE) a novel pipeline for generating synthetic alignment and red-teaming data. Existing methods fall short in creating nuanced and diverse…

Artificial Intelligence · Computer Science 2024-08-23 Anurakt Kumar , Divyanshu Kumar , Jatan Loya , Nitin Aravind Birur , Tanay Baswa , Sahil Agarwal , Prashanth Harshangi

Sixth-generation (6G) radio access networks (RANs) must enforce strict service-level agreements (SLAs) for heterogeneous slices, yet sudden latency spikes remain difficult to diagnose and resolve with conventional deep reinforcement…

Systems and Control · Electrical Eng. & Systems 2026-02-12 Kavan Fatehi , Mostafa Rahmani Ghourtani , Amir Sonee , Poonam Yadav , Alessandra M Russo , Hamed Ahmadi , Radu Calinescu

Retrieval-Augmented Generation (RAG) enables large language models (LLMs) to access external knowledge sources, but the effectiveness of RAG relies on the coordination between the retriever and the generator. Since these components are…

Computation and Language · Computer Science 2025-09-24 Junlin Wang , Zehao Wu , Shaowei Lu , Yanlan Li , Xinghao Huang

Objective: This study aims to uncover the opaque decision-making process of an artificial intelligence (AI) agent for automatic treatment planning. Approach: We examined a previously developed AI agent based on the Actor-Critic with…

Medical Physics · Physics 2025-08-21 Md Mainul Abrar , Xun Jia , Yujie Chi

We introduce SwiftSage, a novel agent framework inspired by the dual-process theory of human cognition, designed to excel in action planning for complex interactive reasoning tasks. SwiftSage integrates the strengths of behavior cloning and…

Computation and Language · Computer Science 2023-12-07 Bill Yuchen Lin , Yicheng Fu , Karina Yang , Faeze Brahman , Shiyu Huang , Chandra Bhagavatula , Prithviraj Ammanabrolu , Yejin Choi , Xiang Ren

Clinical expertise improves not only by acquiring medical knowledge, but by accumulating experience that yields reusable diagnostic patterns. Recent LLMs-based diagnostic agents have shown promising progress in clinical reasoning for…

Computation and Language · Computer Science 2026-04-09 Bingxuan Li , Simo Du , Yue Guo