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To develop an automated workflow for rectal cancer three-dimensional conformal radiotherapy treatment planning that combines deep-learning(DL) aperture predictions and forward-planning algorithms. We designed an algorithm to automate the…
Medical imaging has revolutionized diagnosis, yet unnecessary procedures are rising, exposing patients to radiation and stress, limiting equitable access, and straining healthcare systems. The American College of Radiology Appropriateness…
Cataract surgery remains one of the most widely performed and effective procedures for vision restoration. Effective surgical planning requires integrating diverse clinical examinations for patient assessment, intraocular lens (IOL)…
As LLM agents transition to autonomous digital coworkers, maintaining deterministic goal-directedness in non-linear multi-turn conversations emerged as an architectural bottleneck. We identify and formalize a systemic failure mode termed…
We present PULSE, a medical reasoning agent that combines a domain-tuned large language model with scientific literature retrieval to support diagnostic decision-making in complex real-world cases. To evaluate its capabilities, we curated a…
Stereotactic body radiotherapy (SBRT) is characterized by delivering a high amount of dose in a short period of time. In SBRT the dose is delivered using open fields (e.g., beam's-eye-view) known as "apertures". Mathematical methods can be…
Complex dialog systems often use retrieved evidence to facilitate factual responses. Such RAG (Retrieval Augmented Generation) systems retrieve from massive heterogeneous data stores that are usually architected as multiple indexes or APIs…
We introduce Plan*RAG, a novel framework that enables structured multi-hop reasoning in retrieval-augmented generation (RAG) through test-time reasoning plan generation. While existing approaches such as ReAct maintain reasoning chains…
What does it mean to plan? Current agentic systems, whether scaffolded workflows or end-to-end policies, rely on reactive decision-making: selecting the next action via a fixed procedure with at most undifferentiated adaptive computation…
Rare diseases represent the long tail of medical imaging, where AI models often fail due to the scarcity of representative training data. In clinical workflows, radiologists frequently consult case reports and literature when confronted…
The emergence of large language models has enabled sophisticated multi-agent systems, yet coordinating their reasoning capabilities through prompt engineering remains challenging. We present a theoretically-grounded framework for dynamic…
PET theranostics is transforming precision oncology, yet treatment response varies substantially; many patients receiving 177Lu-PSMA radioligand therapy (RLT) for metastatic castration-resistant prostate cancer (mCRPC) fail to respond,…
Multiple myeloma is managed through sequential lines of therapy over years to decades, with each decision depending on cumulative disease history distributed across dozens to hundreds of heterogeneous clinical documents. Whether LLM-based…
Large language models are unable to continuously adapt and learn from new data during reasoning at inference time. To address this limitation, we propose that complex reasoning tasks be decomposed into atomic subtasks and introduce SAGE, a…
Despite recent success in applying large language models (LLMs) to electronic health records (EHR), most systems focus primarily on assessment rather than treatment planning. We identify three critical limitations in current approaches:…
Artificial intelligence-based radiation therapy (RT) planning has the potential to reduce planning time and inter-planner variability, improving efficiency and consistency in clinical workflows. Most existing automated approaches rely on…
Agentic retrieval-augmented reasoning pipelines are increasingly used to structure how large language models (LLMs) incorporate external evidence in clinical decision support. These systems iteratively retrieve curated domain knowledge and…
Robotic-assisted surgery (RAS) is central to modern surgery, driving the need for intelligent systems with accurate scene understanding. Most existing surgical AI methods rely on isolated, task-specific models, leading to fragmented…
The integration of Large Language Models (LLMs) into healthcare is constrained by knowledge limitations, hallucinations, and a disconnect from Evidence-Based Medicine (EBM). While Retrieval-Augmented Generation (RAG) offers a solution,…
Retrieval-Augmented Generation (RAG) is widely employed to mitigate risks such as hallucinations and knowledge obsolescence in medical question answering, yet its predominantly single-round, static retrieval paradigm misaligns with the…