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Specialized clinical AI assistants are rapidly entering medical practice, often framed as safer or more reliable than general-purpose large language models (LLMs). Yet, unlike frontier models, these clinical tools are rarely subjected to…

Computation and Language · Computer Science 2025-12-02 Krithik Vishwanath , Mrigayu Ghosh , Anton Alyakin , Daniel Alexander Alber , Yindalon Aphinyanaphongs , Eric Karl Oermann

Security analysts face increasing pressure to triage large and complex vulnerability backlogs. Large Language Models (LLMs) offer a potential aid by automating parts of the interpretation process. We evaluate four models (ChatGPT, Claude,…

Cryptography and Security · Computer Science 2025-10-22 Osama Al Haddad , Muhammad Ikram , Ejaz Ahmed , Young Lee

Large language models (LLMs) have become important tools in solving biological problems, offering improvements in accuracy and adaptability over conventional methods. Several benchmarks have been proposed to evaluate the performance of…

Large Language Models (LLMs) have achieved high accuracy on medical question-answer (QA) benchmarks, yet their capacity for flexible clinical reasoning has been debated. Here, we asked whether advances in reasoning LLMs improve their…

Computation and Language · Computer Science 2026-01-21 Kie Shidara , Preethi Prem , Jonathan Kim , Anna Podlasek , Feng Liu , Ahmed Alaa , Danilo Bernardo

Large language models have been adopted in the medical domain for clinical documentation to reduce clinician burden. However, studies have reported that LLMs often "forget" a significant amount of instruction-following ability when…

Computation and Language · Computer Science 2026-04-03 Mengxian Lyu , Cheng Peng , Ziyi Chen , Mengyuan Zhang , Jieting Li Lu , Yonghui Wu

Large language models (LLMs) are increasingly used in clinical and care settings. This exploratory study investigates whether LLMs exhibit sycophantic behavior - adapting their responses to social expectation signals rather than maintaining…

Computers and Society · Computer Science 2026-05-19 Christian Kolb

Large language models (LLMs) offer significant potential in enhancing psychiatric practice, from improving diagnostic accuracy to streamlining clinical documentation and therapeutic support. However, existing evaluation resources heavily…

Computation and Language · Computer Science 2025-11-25 Aya E. Fouda , Abdelrahamn A. Hassan , Radwa J. Hanafy , Mohammed E. Fouda

There is increasing interest in the application large language models (LLMs) to the medical field, in part because of their impressive performance on medical exam questions. While promising, exam questions do not reflect the complexity of…

Recent advancements in Large Language Models (LLMs) have significantly influenced the landscape of language and speech research. Despite this progress, these models lack specific benchmarking against state-of-the-art (SOTA) models tailored…

Objective To solve major clinical natural language processing (NLP) tasks using a unified text-to-text learning architecture based on a generative large language model (LLM) via prompt tuning. Methods We formulated 7 key clinical NLP tasks…

Computation and Language · Computer Science 2023-12-12 Cheng Peng , Xi Yang , Aokun Chen , Zehao Yu , Kaleb E Smith , Anthony B Costa , Mona G Flores , Jiang Bian , Yonghui Wu

Large language model (LLM) simulations of human behavior have the potential to revolutionize the social and behavioral sciences, if and only if they faithfully reflect real human behaviors. Current evaluations of simulation fidelity are…

Computation and Language · Computer Science 2026-04-14 Tiancheng Hu , Joachim Baumann , Lorenzo Lupo , Nigel Collier , Dirk Hovy , Paul Röttger

Large language models (LLMs) are increasingly central to clinician workflows, spanning clinical decision support, medical education, and patient communication. However, current evaluation methods for medical LLMs rely heavily on static,…

Physicians considering clinical trials for their patients are met with the laborious process of checking many text based eligibility criteria. Large Language Models (LLMs) have shown to perform well for clinical information extraction and…

Machine Learning · Computer Science 2023-06-30 Danny M. den Hamer , Perry Schoor , Tobias B. Polak , Daniel Kapitan

With the emergence of large language models (LLMs), investigating if they can surpass humans in areas such as emotion recognition and empathetic responding has become a focal point of research. This paper presents a comprehensive study…

Computation and Language · Computer Science 2024-06-10 Anuradha Welivita , Pearl Pu

Large language models (LLMs) are increasingly utilized in clinical reasoning and risk assessment. However, their interpretive reliability in critical and indeterminate domains such as psychiatry remains unclear. Prior work has identified…

Machine Learning · Computer Science 2026-04-30 Shevya Panda , Shinjini Bose , Ananya Joshi

Large language models (LLMs) have garnered significant attention and widespread usage due to their impressive performance in various tasks. However, they are not without their own set of challenges, including issues such as hallucinations,…

Computation and Language · Computer Science 2024-05-08 Duygu Altinok

Although supervised machine learning is popular for information extraction from clinical notes, creating large annotated datasets requires extensive domain expertise and is time-consuming. Meanwhile, large language models (LLMs) have…

Computation and Language · Computer Science 2024-01-26 Madhumita Sushil , Travis Zack , Divneet Mandair , Zhiwei Zheng , Ahmed Wali , Yan-Ning Yu , Yuwei Quan , Atul J. Butte

Prognosis prediction is crucial for determining optimal treatment plans for lung cancer patients. Traditionally, such predictions relied on models developed from retrospective patient data. Recently, large language models (LLMs) have gained…

Computation and Language · Computer Science 2024-08-16 Danqing Hu , Bing Liu , Xiang Li , Xiaofeng Zhu , Nan Wu

Large Language Models (LLMs) have significantly advanced Natural Language Processing (NLP), particularly in Natural Language Understanding (NLU) tasks. As we progress toward an agentic world where LLM-based agents autonomously handle…

Computation and Language · Computer Science 2025-04-03 Naimul Haque
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