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Task functional magnetic resonance imaging (fMRI) is a type of neuroimaging data used to identify areas of the brain that activate during specific tasks or stimuli. These data are conventionally modeled using a massive univariate approach…

Methodology · Statistics 2022-11-04 Daniel A. Spencer , David Bolin , Amanda F. Mejia

Multi-electrode arrays (MEAs) can record extracellular action potentials (also known as 'spikes') from hundreds or thousands of neurons simultaneously. Inference of a functional network from a spike train is a fundamental and formidable…

Computational Engineering, Finance, and Science · Computer Science 2020-07-07 Yun Zhao , Richard Jiang , Zhenni Xu , Elmer Guzman , Paul K. Hansma , Linda Petzold

This thesis is dedicated to the statistical analysis of multi-sub ject fMRI data, with the purpose of identifying bain structures involved in certain cognitive or sensori-motor tasks, in a reproducible way across sub jects. To overcome…

Applications · Statistics 2010-05-19 Merlin Keller , Alexis Roche , Marc Lavielle

In this paper, we describe a Bayesian deep neural network (DNN) for predicting FreeSurfer segmentations of structural MRI volumes, in minutes rather than hours. The network was trained and evaluated on a large dataset (n = 11,480), obtained…

Computer Vision and Pattern Recognition · Computer Science 2022-06-16 Patrick McClure , Nao Rho , John A. Lee , Jakub R. Kaczmarzyk , Charles Zheng , Satrajit S. Ghosh , Dylan Nielson , Adam G. Thomas , Peter Bandettini , Francisco Pereira

A major open challenge in neuroscience is the ability to measure and perturb neural activity in vivo from well-defined neural sub-populations at cellular resolution anywhere in the brain. However, limitations posed by scattering and…

Biological Physics · Physics 2017-11-10 Shay Ohayon , Antonio Miguel Caravaca-Aguirre , Rafael Piestun , James J. DiCarlo

(1) Background: The success of physiotherapy depends on the regular and correct performance of movement exercises. A system that automatically evaluates these could support the therapy. Previous approaches in this area rarely rely on Deep…

Machine Learning · Computer Science 2025-06-02 Andreas Spilz , MIchael Munz

Partial synchronization plays a crucial role in the functioning of neuronal networks: selective, coordinated activation of neurons enables information processing that flexibly adapts to a changing computational context. Since the structure…

Neurons and Cognition · Quantitative Biology 2025-06-17 Daniil Radushev , Olesia Dogonasheva , Boris Gutkin , Denis Zakharov

Activity detection is an important task in the next generation grant-free multiple access. While there are a number of existing algorithms designed for this purpose, they mostly require precise information about the network, such as…

Machine Learning · Computer Science 2024-02-05 Hao Zhang , Qingfeng Lin , Yang Li , Lei Cheng , Yik-Chung Wu

Calcium imaging is one of the most important tools in neurophysiology as it enables the observation of neuronal activity for hundreds of cells in parallel and at single-cell resolution. In order to use the data gained with calcium imaging,…

Neurons and Cognition · Quantitative Biology 2020-04-07 Elke Kirschbaum , Alberto Bailoni , Fred A. Hamprecht

Recently, fluorescence-based optical techniques have emerged as a powerful tool to probe information in the mammalian brain. However, tissue heterogeneities prevent clear imaging of deep neuron bodies due to light scattering. While several…

Extracting and detecting spike activities from the fluorescence observations is an important step in understanding how neuron systems work. The main challenge lies in that the combination of the ambient noise with dynamic baseline…

Neurons and Cognition · Quantitative Biology 2019-02-01 Zhuangkun Wei , Bin Li , Weisi Guo , Wenxiu Hu , Chenglin Zhao

Neurons encode information about the environment through their activity. As animals explore the environment, neurons rapidly acquire selectivity for distinct features of the external world; characterizing how these selectivity patterns…

Fluorescent calcium indicators are a popular means for observing the spiking activity of large neuronal populations, but extracting the activity of each neuron from raw fluorescence calcium imaging data is a nontrivial problem. We present a…

Neurons and Cognition · Quantitative Biology 2017-03-17 Johannes Friedrich , Pengcheng Zhou , Liam Paninski

Experiments that study neural encoding of stimuli at the level of individual neurons typically choose a small set of features present in the world --- contrast and luminance for vision, pitch and intensity for sound --- and assemble a…

Machine Learning · Statistics 2016-11-22 Xin , Chen , Jeffrey M Beck , John M Pearson

In the recent past, psychological stress has been increasingly observed in humans, and early detection is crucial to prevent health risks. Stress detection using on-device deep learning algorithms has been on the rise owing to advancements…

Machine Learning · Computer Science 2020-12-07 Abhijith Ragav , Gautham Krishna Gudur

Advances in image registration and machine learning have recently enabled volumetric analysis of postmortem brain tissue from conventional photographs of coronal slabs, which are routinely collected in brain banks and neuropathology…

Semantic segmentation is a crucial task in biomedical image processing, which recent breakthroughs in deep learning have allowed to improve. However, deep learning methods in general are not yet widely used in practice since they require…

Computer Vision and Pattern Recognition · Computer Science 2019-07-12 Melanie Lubrano di Scandalea , Christian S. Perone , Mathieu Boudreau , Julien Cohen-Adad

Deep-learning algorithms enable precise image recognition based on high-dimensional hierarchical image features. Here, we report the development and implementation of a deep-learning-based image segmentation algorithm in an autonomous…

Image and Video Processing · Electrical Eng. & Systems 2020-03-26 Satoru Masubuchi , Eisuke Watanabe , Yuta Seo , Shota Okazaki , Takao Sasagawa , Kenji Watanabe , Takashi Taniguchi , Tomoki Machida

Various brain functions that are necessary to maintain life activities materialize through the interaction of countless neurons. Therefore, it is important to analyze functional neuronal network. To elucidate the mechanism of brain…

Neurons and Cognition · Quantitative Biology 2023-06-29 Shun Kimura , Koujin Takeda

3D functional imaging of neuronal activity in entire organisms at single cell level and physiologically relevant time scales faces major obstacles due to trade-offs between the size of the imaged volumes, and spatial and temporal…