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Fluorescent calcium imaging provides a potentially powerful tool for inferring connectivity in neural circuits with up to thousands of neurons. However, a key challenge in using calcium imaging for connectivity detection is that current…

Information Theory · Computer Science 2014-09-05 Alyson K. Fletcher , Sundeep Rangan

Purpose: To apply a convolutional neural network (CNN) to develop a system that segments intensity calibration phantom regions in computed tomography (CT) images, and to test the system in a large cohort to evaluate its robustness. Methods:…

Computer Vision and Pattern Recognition · Computer Science 2020-12-22 Keisuke Uemura , Yoshito Otake , Masaki Takao , Mazen Soufi , Akihiro Kawasaki , Nobuhiko Sugano , Yoshinobu Sato

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

Neurons and Cognition · Quantitative Biology 2017-03-03 Jannis Schuecker , Maximilian Schmidt , Sacha J. van Albada , Markus Diesmann , Moritz Helias

Large efforts are currently under way to systematically map functional connectivity between all pairs of millimeter-scale brain regions using big volumes of neuroimaging data. Functional magnetic resonance imaging (fMRI) can produce these…

Neurons and Cognition · Quantitative Biology 2014-09-24 Enzo Tagliazucchi , Helmut Laufs , Dante R. Chialvo

The anatomical location of imaging features is of crucial importance for accurate diagnosis in many medical tasks. Convolutional neural networks (CNN) have had huge successes in computer vision, but they lack the natural ability to…

Computer Vision and Pattern Recognition · Computer Science 2016-11-01 Mohsen Ghafoorian , Nico Karssemeijer , Tom Heskes , Inge van Uden , Clara Sanchez , Geert Litjens , Frank-Erik de Leeuw , Bram van Ginneken , Elena Marchiori , Bram Platel

Single-molecule localization fluorescence microscopy constructs super-resolution images by sequential imaging and computational localization of sparsely activated fluorophores. Accurate and efficient fluorophore localization algorithms are…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Artur Speiser , Lucas-Raphael Müller , Ulf Matti , Christopher J. Obara , Wesley R. Legant , Jonas Ries , Jakob H. Macke , Srinivas C. Turaga

Activity recognition computer vision algorithms can be used to detect the presence of autism-related behaviors, including what are termed "restricted and repetitive behaviors", or stimming, by diagnostic instruments. The limited data that…

Computer Vision and Pattern Recognition · Computer Science 2021-01-12 Peter Washington , Aaron Kline , Onur Cezmi Mutlu , Emilie Leblanc , Cathy Hou , Nate Stockham , Kelley Paskov , Brianna Chrisman , Dennis P. Wall

One of the most common tasks in medical imaging is semantic segmentation. Achieving this segmentation automatically has been an active area of research, but the task has been proven very challenging due to the large variation of anatomy…

Computer Vision and Pattern Recognition · Computer Science 2018-04-10 Holger R. Roth , Chen Shen , Hirohisa Oda , Masahiro Oda , Yuichiro Hayashi , Kazunari Misawa , Kensaku Mori

One often lacks sufficient annotated samples for training deep segmentation models. This is in particular the case for less common imaging modalities such as Quantitative Susceptibility Mapping (QSM). It has been shown that deep models tend…

Computer vision tasks are difficult because of the large variability in the data that is induced by changes in light, background, partial occlusion as well as the varying pose, texture, and shape of objects. Generative approaches to…

Computer Vision and Pattern Recognition · Computer Science 2018-11-30 Adam Kortylewski , Mario Wieser , Andreas Morel-Forster , Aleksander Wieczorek , Sonali Parbhoo , Volker Roth , Thomas Vetter

A central goal in many brain studies is the identification of those brain regions that are activated during an observation window that may correspond to a motor task, a stimulus, or simply a resting state. While functional MRI is currently…

Numerical Analysis · Mathematics 2025-10-23 Daniela Calvetti , Erkki Somersalo

Sparse deep learning aims to address the challenge of huge storage consumption by deep neural networks, and to recover the sparse structure of target functions. Although tremendous empirical successes have been achieved, most sparse deep…

Machine Learning · Statistics 2020-11-17 Jincheng Bai , Qifan Song , Guang Cheng

With pervasive applications of medical imaging in health-care, biomedical image segmentation plays a central role in quantitative analysis, clinical diagno- sis, and medical intervention. Since manual anno- tation su ers limited…

Computer Vision and Pattern Recognition · Computer Science 2018-03-14 Xiaowei Xu , Qing Lu , Yu Hu , Lin Yang , Sharon Hu , Danny Chen , Yiyu Shi

In many applications, smooth processes generate data that is recorded under a variety of observation regimes, such as dense, sparse or fragmented observations that are often contaminated with error. The statistical goal of registering and…

Applications · Statistics 2019-12-12 James Matuk , Karthik Bharath , Oksana Chkrebtii , Sebastian Kurtek

While perception tasks such as visual object recognition and text understanding play an important role in human intelligence, the subsequent tasks that involve inference, reasoning and planning require an even higher level of intelligence.…

Machine Learning · Statistics 2016-09-06 Hao Wang , Dit-Yan Yeung

This paper presents a comprehensive evaluation framework for image segmentation algorithms, encompassing naive methods, machine learning approaches, and deep learning techniques. We begin by introducing the fundamental concepts and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Tatiana Merkulova , Bharani Jayakumar

Ultrasound scanning is essential in several medical diagnostic and therapeutic applications. It is used to visualize and analyze anatomical features and structures that influence treatment plans. However, it is both labor intensive, and its…

Computer Vision and Pattern Recognition · Computer Science 2021-06-29 Abdullah F. Al-Battal , Yan Gong , Lu Xu , Timothy Morton , Chen Du , Yifeng Bu 1 , Imanuel R Lerman , Radhika Madhavan , Truong Q. Nguyen

We introduce a novel approach for temporal activity segmentation with timestamp supervision. Our main contribution is a graph convolutional network, which is learned in an end-to-end manner to exploit both frame features and connections…

Computer Vision and Pattern Recognition · Computer Science 2022-08-03 Hamza Khan , Sanjay Haresh , Awais Ahmed , Shakeeb Siddiqui , Andrey Konin , M. Zeeshan Zia , Quoc-Huy Tran

Three-dimensional (3D) fluorescence microscopy in general requires axial scanning to capture images of a sample at different planes. Here we demonstrate that a deep convolutional neural network can be trained to virtually refocus a 2D…

Computer Vision and Pattern Recognition · Computer Science 2019-11-05 Yichen Wu , Yair Rivenson , Hongda Wang , Yilin Luo , Eyal Ben-David , Laurent A. Bentolila , Christian Pritz , Aydogan Ozcan

We introduce a generic framework that reduces the computational cost of object detection while retaining accuracy for scenarios where objects with varied sizes appear in high resolution images. Detection progresses in a coarse-to-fine…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Mingfei Gao , Ruichi Yu , Ang Li , Vlad I. Morariu , Larry S. Davis
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