Related papers: Contactless micro-elastography of single cells usi…
Elasticity is a fundamental cellular property that is related to the anatomy, functionality and pathological state of cells and tissues. However, current techniques based on cell deformation, atomic force microscopy or Brillouin scattering…
Recent advances recognize that the viscoelastic properties of epithelial structures play important roles in biology and disease modeling. However, accessing the viscoelastic properties of multicellular structures in mechanistic or…
Many essential cellular functions depend on the viscoelastic properties of the cytoplasm. While techniques such as optical tweezers and atomic force microscopy can measure these properties, their reliance on localized probes prevents…
Acoustical tweezers open major prospects in microbiology for cells and microorganisms contactless manipulation, organization and mechanical properties testing since they are biocompatible, label-free and can exert forces several orders of…
We present an experimental protocol for the fabrication and characterization of scalable microarchitected elastic waveguides. Using silicon microfabrication techniques, we develop free-standing 2D truss-based architected waveguides with a…
Shear wave elastography involves applying a non-invasive acoustic radiation force to the tissue and imaging the induced deformation to infer its mechanical properties. This work investigates the use of convolutional neural networks to…
We develop and thoroughly test a stress-controlled, parallel plates shear cell that can be coupled to an optical microscope or a small angle light scattering setup, for simultaneous investigation of the rheological properties and the…
When submitted to a magnetic field, micron size wires with superparamagnetic properties behave as embedded rheometers and represent interesting sensors for micro-rheology. Here we use rotational magnetic spectroscopy to measure the shear…
Dynamic elastography is a widely used, safe, convenient, and cost-effective method to aid in medical diagnosis. It visualizes the wave field propagating through living tissues and quantitatively determines the wave propagation speed from…
We report contactless measurements of the viscoelastic rheological properties of soft gels. The experiments are performed using a colloidal-probe Atomic Force Microscope (AFM) in a liquid environment and in dynamic mode. The mechanical…
We present a contactless method for measuring the elastic modulus of living cells (human triple-negative breast cancer, MDA-MB-231) from the thermal fluctuations of an atomic force microscope (AFM) cantilever. By analyzing the power…
Microrheology, the study of fluids on micron length-scales, promises to reveal insights into cellular biology, including mechanical biomarkers of disease and the interplay between biomechanics and cellular function. Here a…
Objective - Shear wave elastography has enriched ultrasound medical imaging with quantitative measurements of tissue stiffness. However, this method still suffers from some limitations due to viscoelasticity, guiding geometry or static…
Sensing biological forces with microscopic lasers is an emerging technique that offers significant advantages over conventional fluorescent probes and imaging-based techniques. However, the limited availability of suitable deformable or…
We present a simple and \emph{non-invasive} experimental procedure to measure the linear viscoelastic properties of cells by passive video particle tracking microrheology. In order to do this, a generalised Langevin equation is adopted to…
Vibrational spectroscopy is a ubiquitous technology that derives the species, constituents, and morphology of an object from its natural vibrations. However, the vibrational spectra of mesoscopic particles - including most biological cells…
Using shear wave elastography, we measure the changes in the wave speed with the stress produced by a striated muscle during isometric voluntary contraction. To isolate the behaviour of an individual muscle from complementary or…
We present an analytical model for the frequency response of a gas microbubble oscillating near a spherical inclusion of arbitrary size and mechanical nature (rigid, fluid, or viscoelastic) immersed in a viscous compressible fluid. The…
The study of the interactions of living adherent cells with mechanically stable (visco)elastic materials enables understanding and exploiting physiological phenomena mediated by cell-extracellular communication. However, insight on the…
Optical coherence elastography (OCE) is a powerful non-invasive imaging technique for high-resolution assessment of tissue elasticity and viscoelasticity. Accurate characterization of viscoelastic properties requires estimating shear wave…