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In this work we propose a deep learning approach to clean spectroscopy signals using only uncleaned data. Cleaning signals from spectroscopy instrument noise is challenging as noise exhibits an unknown, non-zero mean, multivariate…

Machine Learning · Computer Science 2023-01-04 Juan Castorena , Diane Oyen

We introduce a machine learning prediction workflow to study the impact of defects on the Raman response of 2D materials. By combining the use of machine-learned interatomic potentials, the Raman-active $\Gamma$-weighted density of states…

In fluorescence microscopy, spectral unmixing aims to recover individual fluorophore concentrations from spectral images that capture mixed fluorophore emissions. Since classical methods operate pixel-wise and rely on least-squares fitting,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Federico Carrara , Talley Lambert , Mehdi Seifi , Florian Jug

ConvNets achieve good results when training from clean data, but learning from noisy labels significantly degrades performances and remains challenging. Unlike previous works constrained by many conditions, making them infeasible to real…

Computer Vision and Pattern Recognition · Computer Science 2019-08-21 Jiangfan Han , Ping Luo , Xiaogang Wang

Spectroscopy represents the ideal observational method to maximally extract information from galaxies regarding their star formation and chemical enrichment histories. However, absorption spectra of galaxies prove rather challenging at high…

Instrumentation and Methods for Astrophysics · Physics 2025-10-10 Oliver Camilleri , Zahra Sharbaf , Ignacio Ferreras

As the scale and complexity of integrated circuits continue to increase, traditional modeling methods are struggling to address the nonlinear challenges in radio frequency (RF) chips. Deep learning has been increasingly applied to RF device…

Signal Processing · Electrical Eng. & Systems 2024-12-06 Zhaokun Hu , Yindong Xiao , Houjun Wang , Jiayong Yu , Zihang Gao

Image denoising is an important problem in low-level vision and serves as a critical module for many image recovery tasks. Anisotropic diffusion is a wide family of image denoising approaches with promising performance. However, traditional…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Xinran Qin , Yuhui Quan , Ruotao Xu , Hui Ji

The growing field of nano nuclear magnetic resonance (nano-NMR) seeks to estimate spectra or discriminate between spectra of minuscule amounts of complex molecules. While this field holds great promise, nano-NMR experiments suffer from…

Quantum Physics · Physics 2019-12-02 Nati Aharon , Amit Rotem , Liam P. McGuinness , Fedor Jelezko , Alex Retzker , Zohar Ringel

Magnetic Resonance Imaging (MRI) is an essential diagnostic tool in clinical settings but its utility is often hindered by noise artifacts introduced during the imaging process. Effective denoising is critical for enhancing image quality…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Zeyun Deng , Joseph Campbell

This paper proposes a novel method for automatic MRI denoising that exploits last advances in deep learning feature regression and self-similarity properties of the MR images. The proposed method is a two-stage approach. In the first stage,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-19 Jose V. Manjon , Pierrick Coupe

Image denoising is a prerequisite for downstream tasks in many fields. Low-dose and photon-counting computed tomography (CT) denoising can optimize diagnostic performance at minimized radiation dose. Supervised deep denoising methods are…

Machine Learning · Computer Science 2022-01-06 Chuang Niu , Mengzhou Li , Fenglei Fan , Weiwen Wu , Xiaodong Guo , Qing Lyu , Ge Wang

The use of fluorescent molecules to create long sequences of low-density, diffraction-limited images enables highly-precise molecule localization. However, this methodology requires lengthy imaging times, which limits the ability to view…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Yair Ben Sahel , Yonina C. Eldar

Histological analysis of tissue samples is one of the most widely used methods for disease diagnosis. After taking a sample from a patient, it goes through a lengthy and laborious preparation, which stains the tissue to visualize different…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Yair Rivenson , Hongda Wang , Zhensong Wei , Yibo Zhang , Harun Gunaydin , Aydogan Ozcan

Medical image acquisition is often intervented by unwanted noise that corrupts the information content. This paper introduces an unsupervised medical image denoising technique that learns noise characteristics from the available images and…

Image and Video Processing · Electrical Eng. & Systems 2021-03-12 Swati Rai , Jignesh S. Bhatt , S. K. Patra

Low-light image denoising and enhancement are challenging, especially when traditional noise assumptions, such as Gaussian noise, do not hold in majority. In many real-world scenarios, such as low-light imaging, noise is signal-dependent…

Image and Video Processing · Electrical Eng. & Systems 2025-11-03 Isha Rao , Ratul Chakraborty , Sanjay Ghosh

With the development of deep learning, medical image processing has been widely used to assist clinical research. This paper focuses on the denoising problem of low-dose computed tomography using deep learning. Although low-dose computed…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Zhilin Guan , Wei Zhang

Traditional blind image SR methods need to model real-world degradations precisely. Consequently, current research struggles with this dilemma by assuming idealized degradations, which leads to limited applicability to actual user data.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-30 Brian B. Moser , Ahmed Anwar , Federico Raue , Stanislav Frolov , Andreas Dengel

Raman microscopy is a powerful method combining non-invasiveness with no special sample preparation. Because of this remarkable simplicity, it has been widely exploited in many fields, ranging from life and materials sciences, to…

The use of deep learning has successfully solved several problems in the field of medical imaging. Deep learning has been applied to the CT denoising problem successfully. However, the use of deep learning requires large amounts of data to…

Image and Video Processing · Electrical Eng. & Systems 2022-04-04 Mayank Patwari , Ralf Gutjahr , Rainer Raupach , Andreas Maier

Magnetic resonance imaging (MRI) is a powerful noninvasive diagnostic imaging tool that provides unparalleled soft tissue contrast and anatomical detail. Noise contamination, especially in accelerated and/or low-field acquisitions, can…

Image and Video Processing · Electrical Eng. & Systems 2025-05-12 Jiachen Tu , Yaokun Shi , Fan Lam