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Histopathology, the current gold standard for cancer diagnosis, involves the manual examination of tissue samples after chemical staining, a time-consuming process requiring expert analysis. Raman spectroscopy is an alternative, stain-free…
Imaging through scattering is a pervasive and difficult problem in many biological applications. The high background and the exponentially attenuated target signals due to scattering fundamentally limits the imaging depth of fluorescence…
Recently, the mainstream practice for training low-light raw image denoising methods has shifted towards employing synthetic data. Noise modeling, which focuses on characterizing the noise distribution of real-world sensors, profoundly…
Noise reduction techniques based on deep learning have demonstrated impressive performance in enhancing the overall quality of recorded speech. While these approaches are highly performant, their application in audio engineering can be…
Image restoration has been an extensively researched topic in numerous fields. With the advent of deep learning, a lot of the current algorithms were replaced by algorithms that are more flexible and robust. Deep networks have demonstrated…
Denoising is a fundamental challenge in scientific imaging. Deep convolutional neural networks (CNNs) provide the current state of the art in denoising natural images, where they produce impressive results. However, their potential has…
Raman spectroscopy is an important tool in the study of vibrational properties and composition of molecules, peptides and even proteins. Raman spectra can be simulated based on the change of the electronic polarizability with vibrations,…
Fluorescence lifetime imaging microscopy (FLIM) systems are limited by their slow processing speed, low signal-to-noise ratio (SNR), and expensive and challenging hardware setups. In this work, we demonstrate applying a denoising…
Ultrasound images are widespread in medical diagnosis for musculoskeletal, cardiac, and obstetrical imaging due to the efficiency and non-invasiveness of the acquisition methodology. However, the acquired images are degraded by acoustic…
Supervised learning-based methods yield robust denoising results, yet they are inherently limited by the need for large-scale clean/noisy paired datasets. The use of unsupervised denoisers, on the other hand, necessitates a more detailed…
Hyperspectral stimulated Raman scattering (SRS) microscopy is a label-free technique for biomedical and mineralogical imaging which can suffer from low signal to noise ratios. Here we demonstrate the use of an unsupervised deep learning…
Raman spectroscopy serves as a powerful and reliable tool for analyzing the chemical information of substances. The integration of Raman spectroscopy with deep learning methods enables rapid qualitative and quantitative analysis of…
Capturing images under extremely low-light conditions poses significant challenges for the standard camera pipeline. Images become too dark and too noisy, which makes traditional image enhancement techniques almost impossible to apply. Very…
Among the plethora of techniques devised to curb the prevalence of noise in medical images, deep learning based approaches have shown the most promise. However, one critical limitation of these deep learning based denoisers is the…
While deep neural networks have been shown to perform remarkably well in many machine learning tasks, labeling a large amount of ground truth data for supervised training is usually very costly to scale. Therefore, learning robust…
Fingerprint image denoising is a very important step in fingerprint identification. to improve the denoising effect of fingerprint image,we have designs a fingerprint denoising algorithm based on deep encoder-decoder network,which encoder…
Two-dimensional electronic spectroscopy (2DES) has enabled significant discoveries in both biological and synthetic energy-transducing systems. Although deriving chemical information from 2DES is a complex task, machine learning (ML) offers…
This work proposes a learning-based statistical refinement method for improving the denoising results of a given denoiser without knowing the precise noise distribution or accessing clean images or calibration data. While there are many…
Enhancing the visibility in extreme low-light environments is a challenging task. Under nearly lightless condition, existing image denoising methods could easily break down due to significantly low SNR. In this paper, we systematically…
Raman spectroscopy provides spectral information related to the specific molecular structures of substances and has been well established as a powerful tool for studying biological tissues and diagnosing diseases. This article reviews…