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Mamba, a special case of the State Space Model, is gaining popularity as an alternative to template-based deep learning approaches in medical image analysis. While transformers are powerful architectures, they have drawbacks, including…

Multiple Instance Learning (MIL) plays a significant role in computational pathology, enabling weakly supervised analysis of Whole Slide Image (WSI) datasets. The field of WSI analysis is confronted with a severe long-tailed distribution…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Xitong Ling , Yifeng Ping , Jiawen Li , Jing Peng , Yuxuan Chen , Minxi Ouyang , Yizhi Wang , Yonghong He , Tian Guan , Xiaoping Liu , Lianghui Zhu

Foundation models, now powering most of the exciting applications in deep learning, are almost universally based on the Transformer architecture and its core attention module. Many subquadratic-time architectures such as linear attention,…

Machine Learning · Computer Science 2024-06-03 Albert Gu , Tri Dao

Being able to learn on weakly labeled data, and provide interpretability, are two of the main reasons why attention-based deep multiple instance learning (ABMIL) methods have become particularly popular for classification of…

Computer Vision and Pattern Recognition · Computer Science 2022-03-09 Axel Andersson , Nadezhda Koriakina , Nataša Sladoje , Joakim Lindblad

Mamba, a State Space Model (SSM) that accelerates training by recasting recurrence as a parallel scan, has recently emerged as a linearly-scaling alternative to self-attention. Because of its unidirectional nature, each state in Mamba only…

Computer Vision and Pattern Recognition · Computer Science 2025-11-13 Jingwei Zhang , Xi Han , Hong Qin , Mahdi S. Hosseini , Dimitris Samaras

Traditional image-based survival prediction models rely on discriminative patch labeling which make those methods not scalable to extend to large datasets. Recent studies have shown Multiple Instance Learning (MIL) framework is useful for…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Jiawen Yao , Xinliang Zhu , Jitendra Jonnagaddala , Nicholas Hawkins , Junzhou Huang

Multi-modal medical image synthesis involves nonlinear transformation of tissue signals between source and target modalities, where tissues exhibit contextual interactions across diverse spatial distances. As such, the utility of a network…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Omer F. Atli , Bilal Kabas , Fuat Arslan , Arda C. Demirtas , Mahmut Yurt , Onat Dalmaz , Tolga Çukur

Few-shot class-incremental learning (FSCIL) aims to incrementally learn novel classes from limited examples while preserving knowledge of previously learned classes. Existing methods face a critical dilemma: static architectures rely on a…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Xiaojie Li , Yibo Yang , Jianlong Wu , Yue Yu , Ming-Hsuan Yang , Liqiang Nie , Min Zhang

Accurate lesion segmentation in histopathology images is essential for diagnostic interpretation and quantitative analysis, yet it remains challenging due to the limited availability of costly pixel-level annotations. To address this, we…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Hangbei Cheng , Xiaorong Dong , Xueyu Liu , Jianan Zhang , Xuetao Ma , Mingqiang Wei , Liansheng Wang , Junxin Chen , Yongfei Wu

Multiple instance learning (MIL) has been extensively applied to whole slide histopathology image (WSI) analysis. The existing aggregation strategy in MIL, which primarily relies on the first-order distance (e.g., mean difference) between…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Yihang Chen , Tsai Hor Chan , Guosheng Yin , Yuming Jiang , Lequan Yu

3D object detection is critical for autonomous driving, yet it remains fundamentally challenging to simultaneously maximize computational efficiency and capture long-range spatial dependencies. We observed that Mamba-based models, with…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Longhui Zheng , Qiming Xia , Xiaolu Chen , Zhaoliang Liu , Chenglu Wen

Physics-informed machine learning (PIML) has emerged as a promising alternative to classical methods for predicting dynamical systems, offering faster and more generalizable solutions. However, existing models, including recurrent neural…

Machine Learning · Computer Science 2025-01-28 Zheyuan Hu , Nazanin Ahmadi Daryakenari , Qianli Shen , Kenji Kawaguchi , George Em Karniadakis

Sequence modeling plays a vital role across various domains, with recurrent neural networks being historically the predominant method of performing these tasks. However, the emergence of transformers has altered this paradigm due to their…

In digital pathology, Whole Slide Image (WSI) analysis is usually formulated as a Multiple Instance Learning (MIL) problem. Although transformer-based architectures have been used for WSI classification, these methods require modifications…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Juan I. Pisula , Katarzyna Bozek

Digital pathology has revolutionized the field by enabling the digitization of tissue samples into whole slide images (WSIs). However, the high resolution and large size of WSIs present significant challenges when it comes to applying Deep…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Ali Mammadov , Loïc Le Folgoc , Guillaume Hocquet , Pietro Gori

Whole slide image (WSI) assessment is a challenging and crucial step in cancer diagnosis and treatment planning. WSIs require high magnifications to facilitate sub-cellular analysis. Precise annotations for patch- or even pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Simon Holdenried-Krafft , Peter Somers , Ivonne A. Montes-Majarro , Diana Silimon , Cristina Tarín , Falko Fend , Hendrik P. A. Lensch

Multiple-instance Learning (MIL) is commonly used to undertake computational pathology (CPath) tasks, and the use of multi-scale patches allows diverse features across scales to be learned. Previous studies using multi-scale features in…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Shuyang Wu , Yifu Qiu , Ines P. Nearchou , Sandrine Prost , Jonathan A Fallowfield , Hakan Bilen , Timothy J Kendall

The Transformer architecture has shown a remarkable ability in modeling global relationships. However, it poses a significant computational challenge when processing high-dimensional medical images. This hinders its development and…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Zhaohu Xing , Tian Ye , Yijun Yang , Guang Liu , Lei Zhu

Although hyperspectral image (HSI) classification is critical for supporting various environmental applications, it is a challenging task due to the spectral-mixture effect, the spatial-spectral heterogeneity and the difficulty to preserve…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Yimin Zhu , Lincoln Linlin Xu

Recent advancements in Mamba have shown promising results in image restoration. These methods typically flatten 2D images into multiple distinct 1D sequences along rows and columns, process each sequence independently using selective scan…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Boyun Li , Haiyu Zhao , Wenxin Wang , Peng Hu , Yuanbiao Gou , Xi Peng
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