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Large language models (LLMs) enable waveform-to-text ECG interpretation and interactive clinical questioning, yet most ECG-LLM systems still rely on weak signal-text alignment and retrieval without explicit physiological or causal…

Uncertainty quantification is a critical yet unsolved challenge for deep learning, especially for the time series imputation with irregularly sampled measurements. To tackle this problem, we propose a novel framework based on the principles…

Machine Learning · Computer Science 2023-06-05 Shweta Dahale , Sai Munikoti , Balasubramaniam Natarajan

Time series data with missing values is common across many domains. Healthcare presents special challenges due to prolonged periods of sensor disconnection. In such cases, having a confidence measure for imputed values is critical. Most…

Machine Learning · Computer Science 2025-07-15 Addison Weatherhead , Anna Goldenberg

To analyze multivariate time series, most previous methods assume regular subsampling of time series, where the interval between adjacent measurements and the number of samples remain unchanged. Practically, data collection systems could…

Machine Learning · Computer Science 2023-10-18 Yuxi Wei , Juntong Peng , Tong He , Chenxin Xu , Jian Zhang , Shirui Pan , Siheng Chen

Learning transferable representations from unlabeled time series is crucial for improving performance in data-scarce classification. Existing self-supervised methods often operate at the point level and rely on unidirectional encoding,…

Machine Learning · Computer Science 2026-03-02 Mingyue Cheng , Xiaoyu Tao , Zhiding Liu , Qi Liu , Hao Zhang , Rujiao Zhang , Enhong Chen

Deployed language models must decide not only what to answer but also when not to answer. We present UniCR, a unified framework that turns heterogeneous uncertainty evidence including sequence likelihoods, self-consistency dispersion,…

Computation and Language · Computer Science 2025-12-30 Markus Oehri , Giulia Conti , Kaviraj Pather , Alexandre Rossi , Laia Serra , Adrian Parody , Rogvi Johannesen , Aviaja Petersen , Arben Krasniqi

The automated analysis of medical time series, such as the electrocardiogram (ECG), electroencephalogram (EEG), pulse oximetry, etc, has the potential to serve as a valuable tool for diagnostic decisions, allowing for remote monitoring of…

Time series data is prevalent in a wide variety of real-world applications and it calls for trustworthy and explainable models for people to understand and fully trust decisions made by AI solutions. We consider the problem of building…

Machine Learning · Computer Science 2020-11-25 Tsung-Yu Hsieh , Suhang Wang , Yiwei Sun , Vasant Honavar

Time Series Foundation Models (TSFMs) have achieved remarkable success through large-scale pretraining. However, their design primarily targets real-valued series, limiting their ability to handle general forecasting tasks involving diverse…

Machine Learning · Computer Science 2026-03-25 Lu Han , Yu Liu , Lan Li , Qiwen Deng , Jian Jiang , Yinbo Sun , Zhe Yu , Binfeng Wang , Xingyu Lu , Lintao Ma , Han-Jia Ye , De-Chuan Zhan

Medical time series data, such as EEG and ECG, are vital for diagnosing neurological and cardiovascular diseases. However, their precise interpretation faces significant challenges due to high annotation costs, leading to data scarcity, and…

Machine Learning · Computer Science 2026-01-13 Kaito Tanaka , Aya Nakayama , Masato Ito , Yuji Nishimura , Keisuke Matsuda

Time series anomaly detection is important in modern large-scale systems and is applied in a variety of domains to analyze and monitor the operation of diverse systems. Unsupervised approaches have received widespread interest, as they do…

Machine Learning · Computer Science 2025-10-23 Buang Zhang , Tung Kieu , Xiangfei Qiu , Chenjuan Guo , Jilin Hu , Aoying Zhou , Christian S. Jensen , Bin Yang

Deep learning methods are powerful tools in classifying multivariate time series data. Despite their high performance, these methods are hard to interpret, which diminishes their applications in high-risk domains such as healthcare. In this…

Machine Learning · Computer Science 2026-05-11 Bhavesh Kalisetti , Vincent Wang , Gaurav R. Ghosal , Maryam Bijanzadeh , Reza Abbasi-Asl

Counterfactual explanation is an important Explainable AI technique to explain machine learning predictions. Despite being studied actively, existing optimization-based methods often assume that the underlying machine-learning model is…

Artificial Intelligence · Computer Science 2022-06-01 Wenzhuo Yang , Jia Li , Caiming Xiong , Steven C. H. Hoi

Real-world time series data often exhibits substantial missing values, posing challenges for advanced analysis. A common approach to addressing this issue is imputation, where the primary challenge lies in determining the appropriate values…

Machine Learning · Computer Science 2025-12-02 Ying Liu , Peng Cui , Wenbo Hu , Richang Hong

Although deep learning has advanced automated electrocardiogram (ECG) diagnosis, prevalent supervised methods typically treat recordings as undifferentiated one-dimensional (1D) signals or two-dimensional (2D) images. This formulation…

Machine Learning · Computer Science 2026-01-13 Runze Ma , Caizhi Liao

As black box models and pretrained models gain traction in time series applications, understanding and explaining their predictions becomes increasingly vital, especially in high-stakes domains where interpretability and trust are…

Machine Learning · Computer Science 2026-01-16 Khalid Oublal , Quentin Bouniot , Qi Gan , Stephan Clémençon , Zeynep Akata

Major postoperative complications are devastating to surgical patients. Some of these complications are potentially preventable via early predictions based on intraoperative data. However, intraoperative data comprise long and fine-grained…

Machine Learning · Computer Science 2022-10-11 Dingwen Li , Bing Xue , Christopher King , Bradley Fritz , Michael Avidan , Joanna Abraham , Chenyang Lu

Uncertainty Quantification aims to determine when the prediction from a Machine Learning model is likely to be wrong. Computer Vision research has explored methods for determining epistemic uncertainty (also known as model uncertainty),…

Machine Learning · Computer Science 2024-03-15 Prithviraj Manivannan , Ivo Pascal de Jong , Matias Valdenegro-Toro , Andreea Ioana Sburlea

Multivariate time series (MTS) classification is foundational to pervasive computing and financial analysis, yet existing multi-scale paradigms are often constrained by suboptimal representation fidelity. We identify two critical…

Machine Learning · Computer Science 2026-05-22 Fan Zhang , Yating Cui , Hua Wang

Machine learning is increasingly applied in high-stakes decision making that directly affect people's lives, and this leads to an increased demand for systems to explain their decisions. Explanations often take the form of counterfactuals,…

Machine Learning · Computer Science 2021-05-20 Maximilian Schleich , Zixuan Geng , Yihong Zhang , Dan Suciu