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Recent advancements in the ability to construct three-dimensional (3D) tissues and organoids from stem cells and biomaterials have not only opened abundant new research avenues in disease modeling and regenerative medicine but also have…

Tissues and Organs · Quantitative Biology 2017-07-27 Richard J. McMurtrey

Transformer-based deep neural networks have achieved remarkable success across various computer vision tasks, largely attributed to their long-range self-attention mechanism and scalability. However, most transformer architectures embed…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Muyi Bao , Changyu Zeng , Yifan Wang , Zhengni Yang , Zimu Wang , Guangliang Cheng , Jun Qi , Wei Wang

Properties of crystalline materials are closely linked to microstructure arising from the spatial arrangement, orientation, and phase of nanocrystals. Rapid characterization of crystalline microstructure can accelerate the identification of…

Materials Science · Physics 2026-02-16 Kwanghwi Je , Ellis R. Kennedy , Sungin Kim , Yao Yang , Erik H. Thiede

Understanding the morphological structure of medical images and precisely segmenting the region of interest or abnormality is an important task that can assist in diagnosis. However, the unique properties of medical imaging make clear…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Sungmin Kang , Jaeha Song , Jihie Kim

Transformer-based neural networks have surpassed promising performance on many biomedical image segmentation tasks due to a better global information modeling from the self-attention mechanism. However, most methods are still designed for…

Computer Vision and Pattern Recognition · Computer Science 2023-02-02 Zheyuan Zhang , Ulas Bagci

Recovering 3D phase features of complex, multiple-scattering biological samples traditionally sacrifices computational efficiency and processing time for physical model accuracy and reconstruction quality. This trade-off hinders the rapid…

Image and Video Processing · Electrical Eng. & Systems 2021-03-30 Alex Matlock , Lei Tian

Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…

Abdominal multi-organ segmentation in computed tomography (CT) is crucial for many clinical applications including disease detection and treatment planning. Deep learning methods have shown unprecedented performance in this perspective.…

Image and Video Processing · Electrical Eng. & Systems 2023-09-29 Mingjin Chen , Yongkang He , Yongyi Lu

Diffusion MRI (dMRI) provides unique insights into fetal brain microstructure in utero. Longitudinal and cross-sectional fetal dMRI studies can reveal crucial neurodevelopmental changes but require precise spatial alignment across scans and…

Image and Video Processing · Electrical Eng. & Systems 2025-05-13 Bo Li , Qi Zeng , Simon K. Warfield , Davood Karimi

The placenta is a complex organ, playing multiple roles during fetal development. Very little is known about the association between placental morphological abnormalities and fetal physiology. In this work, we present an open sourced,…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Michael Ferlaino , Craig A. Glastonbury , Carolina Motta-Mejia , Manu Vatish , Ingrid Granne , Stephen Kennedy , Cecilia M. Lindgren , Christoffer Nellåker

"Epigenetic Tracking" is a model of systems of biological cells, able to generate arbitrary 2 or 3-dimensional cellular shapes of any kind and complexity (in terms of number of cells, number of colours, etc.) starting from a single cell. If…

Adaptation and Self-Organizing Systems · Physics 2011-11-18 Alessandro Fontana

We present feature finding and tracking algorithms in 3D in living cells, and demonstrate their utility to measure metrics important in cell biological processes. We developed a computational imaging hybrid approach that combines automated…

Biological Physics · Physics 2015-04-06 Kemp Plumb , Sarah Elaz , Vincent Pelletier , Maria L. Kilfoil

During development, cell fates are determined through a combination of intracellular transcriptional regulations and extracellular signaling. As a result, spatial patterns of different cell types arise. We investigate the decision between…

Cell Behavior · Quantitative Biology 2021-11-03 Simon Schardt , Sabine C. Fischer

Through mechanical forces, biological cells remodel the surrounding collagen network, generating striking deformation patterns. Tethers-tracts of high densification and fiber alignment-form between cells, thinner bands emanate from cell…

In this study, we build upon a previously proposed neuroevolution framework to evolve deep convolutional models. Specifically, the genome encoding and the crossover operator are extended to make them applicable to layered networks. We also…

Neural and Evolutionary Computing · Computer Science 2021-04-13 Alexander Hadjiivanov , Alan Blair

The membrane curvature of cells and intracellular compartments continuously adapts to enable cells to perform vital functions, from cell division to signal trafficking. Understanding how membrane geometry affects these processes in vivo is…

Reconstructing neuron morphology from 3D light microscope imaging data is critical to aid neuroscientists in analyzing brain networks and neuroanatomy. With the boost from deep learning techniques, a variety of learning-based segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-02-18 Yik San Cheng , Runkai Zhao , Heng Wang , Hanchuan Peng , Yui Lo , Yuqian Chen , Lauren J. O'Donnell , Weidong Cai

Convolutional neural networks have made significant progresses in edge detection by progressively exploring the context and semantic features. However, local details are gradually suppressed with the enlarging of receptive fields. Recently,…

Computer Vision and Pattern Recognition · Computer Science 2022-03-17 Mengyang Pu , Yaping Huang , Yuming Liu , Qingji Guan , Haibin Ling

Pretraining molecular representations from large unlabeled data is essential for molecular property prediction due to the high cost of obtaining ground-truth labels. While there exist various 2D graph-based molecular pretraining approaches,…

Machine Learning · Computer Science 2023-09-11 Sungjun Cho , Dae-Woong Jeong , Sung Moon Ko , Jinwoo Kim , Sehui Han , Seunghoon Hong , Honglak Lee , Moontae Lee

We propose Clustering Mask Transformer (CMT-DeepLab), a transformer-based framework for panoptic segmentation designed around clustering. It rethinks the existing transformer architectures used in segmentation and detection; CMT-DeepLab…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Qihang Yu , Huiyu Wang , Dahun Kim , Siyuan Qiao , Maxwell Collins , Yukun Zhu , Hartwig Adam , Alan Yuille , Liang-Chieh Chen