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We present atomistic molecular dynamics results for fully hydrated bilayers composed of ceramide NS-24:0, free fatty acid 24:0 and cholesterol, to address the effect of the different components in the stratum corneum (the outermost layer of…

Soft Condensed Matter · Physics 2015-05-13 Chinmay Das , Massimo G. Noro , Peter D. Olmsted

We use a simple and efficient computer model to investigate the physical properties of bilayer membranes. The amphiphilic molecules are modeled as short rigid trimers with finite range pair interactions between them. The pair potentials…

Soft Condensed Matter · Physics 2009-11-10 Oded Farago

Detailed understanding of the coupling between fluid flow and solid deformation in porous media is crucial for the development biomedical devices and novel energy technologies relating to a wide range of geological and biological processes.…

Fluid Dynamics · Physics 2021-09-22 Francisco J. Carrillo

The statistical physics and dynamics of double supported bilayers are studied theoretically. The main goal in designing double supported lipid bilayers is to obtain model systems of biomembranes: the upper bilayer is meant to be almost…

Soft Condensed Matter · Physics 2015-03-13 Manoel Manghi , Nicolas Destainville

In the laminar mode interactions among molecules generate friction between layers of water that slide with respect to each other. This friction triggers the shear stress, which is traditionally presumed to be linearly proportional to the…

Fluid Dynamics · Physics 2012-06-21 K. Y. Volokh

A formal derivation of linear hydrodynamics for a granular fluid is given. The linear response to small spatial perturbations of the homogeneous reference state is studied in detail using methods of non-equilibrium statistical mechanics. A…

Statistical Mechanics · Physics 2007-05-23 James W. Dufty , Aparna Baskaran , J. Javier Brey

The study of interactions between biomimetic membranes and micron-sized particles is crucial for understanding various biological processes. Here, we control microparticle spontaneous engulfment by giant lipid vesicles by tuning particle…

Soft Condensed Matter · Physics 2025-01-22 Clément Marque , Gaetano D'Avino , Domenico Larobina , Aude Michel , Ali Abou-Hassan , Antonio Stocco

In this paper we propose a stable and robust strategy to approximate the 3d incompressible hydrostatic Euler and Navier-Stokes systems with free surface. Compared to shallow water approximation of the Navier-Stokes system, the idea is to…

Vesicles and many biological membranes are made of two monolayers of lipid molecules and form closed lipid bilayers. The dynamical behaviour of vesicles is very complex and a variety of forms and shapes appear. Lipid bilayers can be…

Computational Physics · Physics 2015-11-11 John W. Barrett , Harald Garcke , Robert Nürnberg

Bridging the gap between atomistic detail and continuum mechanics is a central challenge in modeling biological membranes, particularly for mesoscopic phenomena spanning large length and time scales. In this work, we introduce a new,…

Soft Condensed Matter · Physics 2026-03-02 Pietro Sillano , Siewert-Jan Marrink , Timon Idema

Lipid structures exhibit complex and highly dynamic lateral structure; and changes in lipid density and fluidity are believed to play an essential role in membrane targeting and function. The dynamic structure of liquids on the molecular…

Soft Condensed Matter · Physics 2016-12-21 Neda Dadashvand , Christina M. Othon

Lipid bilayer membranes are commonly modeled as area-preserving fluid surfaces that resist bending. There appear to be two schools of thought in the literature concerning the actual area constraint. In some works the total or global area…

Biological Physics · Physics 2015-06-23 Sanjay Dharmavaram , Timothy J. Healey

When a colloidal particle adheres to a fluid membrane, it induces elastic deformations in the membrane which oppose its own binding. The structural and energetic aspects of this balance are theoretically studied within the framework of a…

Soft Condensed Matter · Physics 2009-11-10 Markus Deserno

We derive a continuum sharp-interface model for moving contact lines with soluble surfactants in a thermodynamically consistent framework. The model consists of the isothermal two-phase incompressible Navier-Stokes equations for the fluid…

Fluid Dynamics · Physics 2021-08-11 Quan Zhao , Weiqing Ren , Zhen Zhang

In this paper, we consider a simplified Ericksen-Leslie model for the nematic liquid crystal flow. The evolution system consists of the Navier-Stokes equations coupled with a convective Ginzburg-Landau type equation for the averaged…

Analysis of PDEs · Mathematics 2013-05-07 Maurizio Grasselli , Hao Wu

We study a model for lipid-bilayer membrane vesicles exhibiting phase separation, incorporating a phase field together with membrane fluidity and bending elasticity. We prove the existence of a plethora of equilibria in the large,…

Analysis of PDEs · Mathematics 2015-09-18 Timothy J. Healey , Sanjay Dharmavaram

We study the motion of a compressible heat-conducting fluid in three dimensions interacting with a non-linear flexible shell. The fluid is described by the full Navier--Stokes--Fourier system. The shell constitutes an unknown part of the…

Analysis of PDEs · Mathematics 2021-11-18 Dominic Breit , Sebastian Schwarzacher

Giant unilamellar vesicles (GUVs) composed of as few as three lipid species can phase separate into small-scale lipid domains with stripes and dots patterns. These patterns have been experimentally characterized in terms of how their size…

Soft Condensed Matter · Physics 2025-05-21 Qiwei Yu , Andrej Košmrlj

We use a lattice model of a ternary mixture containing saturated and unsaturated lipids with cholesterol (Chol), to study the structural properties characterizing the coexistence between the liquid-disordered and liquid-ordered phases.…

Soft Condensed Matter · Physics 2023-10-24 Tanmoy Sarkar , Oded Farago

Biomembranes and vesicles consisting of multiple phases can attain a multitude of shapes, undergoing complex shape transitions. We study a Cahn--Hilliard model on an evolving hypersurface coupled to Navier--Stokes equations on the surface…

Numerical Analysis · Mathematics 2019-11-01 John W. Barrett , Harald Garcke , Robert Nürnberg