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Low-intensity Transcranial Ultrasonic Stimulation (TUS) is a non-invasive brain stimulation technique enabling cortical and deep brain targeting with unprecedented spatial accuracy. Given the high rate of adoption by new users with varying…

Acquisition of fine motor skills is a time-consuming process as it requires frequent repetitions. Transcranial electrical stimulation is a promising means of enhancing simple motor skill development via neuromodulatory mechanisms. Here, we…

Noninvasive brain stimulation (NIBS) encompasses transcranial stimulation techniques that can influence brain excitability. These techniques have the potential to treat conditions like depression, anxiety, and chronic pain, and to provide…

Digital Libraries · Computer Science 2023-10-11 Swathi Anil , Jennifer D'Souza

During the last three decades, many studies have been conducted in the field of treatment with non-invasive methods. In this way, researchers try to use alternative methods including the use of electromagnetic waves in the treatment of…

Signal Processing · Electrical Eng. & Systems 2022-08-23 Arsalan Heidarpanah

This study evaluated transcranial temporal interference stimulation (tTIS) for focal targeting of the insula and hippocampus, which are clinically relevant yet anatomically difficult to stimulate. Individualized and group-level electrode…

Medical Physics · Physics 2025-10-28 Taiga Inoue , Naofumi Otsuru , Akimasa Hirata

Background: Trans-spinal FUS (tsFUS) has recently been shown promise in modulating spinal reflexes in rodents, opening new avenues for spinal cord interventions in motor control and pain management. However, anatomical differences between…

Medical Physics · Physics 2025-07-09 Koharu Isomura , Wenwei Yu , Jose Gomez-Tames

Transcranial ultrasonic stimulation (TUS) has the potential to usher in a new era for human neuroscience by allowing spatially precise and high-resolution non-invasive targeting of both deep and superficial brain regions. Currently,…

Transcranial ultrasonic stimulation (TUS) is rapidly gaining traction for non-invasive human neuromodulation, with a pressing need to establish protocols that maximise neuromodulatory efficacy. In this review, we aggregate and examine…

Biological Physics · Physics 2024-07-04 Tulika Nandi , Benjamin R. Kop , Kim Butts Pauly , Charlotte J. Stagg , Lennart Verhagen

Transcranial magnetic stimulation (TMS) is a noninvasive medical procedure that can modulate brain activity, and it is widely used in neuroscience and neurology research. Compared to manual operators, robots may improve the outcome of TMS…

Personalized treatments are gaining momentum across all fields of medicine. Precision medicine can be applied to neuromodulatory techniques, where focused brain stimulation treatments such as repetitive transcranial magnetic stimulation…

Neurostimulation technologies have seen a recent surge in interest from the neuroscience and controls communities alike due to their proven potential to treat conditions such as Parkinson's Disease, and depression. The provided stimulation…

Systems and Control · Electrical Eng. & Systems 2023-01-03 Gagan Acharya , Sebastian F. Ruf , Erfan Nozari

The present literature about possible mechanisms behind the effectivity of noninvasive electromagnetic stimulation in major depressive disorder (MDD) is not very rich. Despite extensive research in applications for clinical practice, the…

Neurons and Cognition · Quantitative Biology 2019-12-19 Milena Cukic

Background: Transcranial magnetic stimulation (TMS) is a powerful tool to investigate neurophysiology of the human brain and treat brain disorders. Traditionally, therapeutic TMS has been applied in a one-size-fits-all approach,…

Transcranial direct current stimulation (tDCS) has emerged as a promising non-invasive therapeutic intervention for major depressive disorder (MDD), yet its effects on neural mechanisms remain incompletely understood. This study…

Quantitative Methods · Quantitative Biology 2025-04-29 Vishwani Singh , Rohit Verma , Shaurya Shriyam , Tapan K. Gandhi

Concurrency of transcranial magnetic stimulation with electroencephalography (TMS-EEG) technique is a powerful and challenging methodology for basic research and clinical applications. Aspects considered in experiments for effective TMS-EEG…

Neurons and Cognition · Quantitative Biology 2024-03-18 Hua Cheng

Brain stimulation is a core method in neuroscience. Numerous non-invasive brain stimulation (NIBS) techniques are currently in use in basic and clinical research, and recent advances promise the ability to non-invasively access deep brain…

Neurons and Cognition · Quantitative Biology 2021-11-02 Sebastian J Lehmann , Brian D Corneil

Transcranial Electrical Stimulation (TCES) and Deep Brain Stimulation (DBS) are two different applications of electrical current to the brain used in different areas of medicine. Both have a similar frequency dependence of their efficiency,…

Neurons and Cognition · Quantitative Biology 2019-07-15 Markus Schütt , Jens Christian Claussen

Noninvasive brain stimulation (NIBS) by quasistatic electromagnetic means is presently comprised of two methods: Magnetic induction methods (Transcranial magnetic perturbation or TMP) and electrical contact methods (Transcranial electric…

Medical Physics · Physics 2020-06-11 D. J. Sheltraw , B. Inglis , L. Labruna , R. Ivry

Since four decades ago, that the transcranial magnetic stimulation (TMS) technique was introduced, the increasing attention of neuroscience researchers and medical engineers has been focused on the development of this technique and its use…

Signal Processing · Electrical Eng. & Systems 2022-08-31 Arsalan Heidarpanah

Accurate neuronavigation is critical for effective transcranial magnetic stimulation (TMS), as stimulation outcomes depend directly on precise coil placement. Existing neuronavigation systems are often costly, complex, and prone to tracking…

Human-Computer Interaction · Computer Science 2026-01-26 Xuyi Hu , Ke Ma , Siwei Liu , Per Ola Kristensson , Stefan Goetz