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Tumor synthesis can generate examples that AI often misses or over-detects, improving AI performance by training on these challenging cases. However, existing synthesis methods, which are typically unconditional -- generating images from…

Image and Video Processing · Electrical Eng. & Systems 2024-12-25 Xinran Li , Yi Shuai , Chen Liu , Qi Chen , Qilong Wu , Pengfei Guo , Dong Yang , Can Zhao , Pedro R. A. S. Bassi , Daguang Xu , Kang Wang , Yang Yang , Alan Yuille , Zongwei Zhou

While hundreds of artificial intelligence (AI) algorithms are now approved or cleared by the US Food and Drugs Administration (FDA), many studies have shown inconsistent generalization or latent bias, particularly for underrepresented…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Luke W. Sagers , James A. Diao , Luke Melas-Kyriazi , Matthew Groh , Pranav Rajpurkar , Adewole S. Adamson , Veronica Rotemberg , Roxana Daneshjou , Arjun K. Manrai

Synthetic data generation in histopathology faces unique challenges: preserving tissue heterogeneity, capturing subtle morphological features, and scaling to unannotated datasets. We present a latent diffusion model that generates realistic…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Saghir Alfasly , Wataru Uegami , MD Enamul Hoq , Ghazal Alabtah , H. R. Tizhoosh

Reliable crack detection and segmentation are vital for structural health monitoring, yet the scarcity of well-annotated data constitutes a major challenge. To address this limitation, we propose a novel context-aware generative framework…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Nassim Sadallah , Mohand Saïd Allili

Advancements in generative models have sparked significant interest in generating images while adhering to specific structural guidelines. Scene graph to image generation is one such task of generating images which are consistent with the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Rameshwar Mishra , A V Subramanyam

Deep learning is widely applied in computer-aided pathological diagnosis, which alleviates the pathologist workload and provide timely clinical analysis. However, most models generally require large-scale annotated data for training, which…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Zeyu Liu , Tianyi Zhang , Yufang He , Yunlu Feng , Yu Zhao , Guanglei Zhang

Convolutional Neural Networks (CNNs) can play a key role in Medical Image Analysis under large-scale annotated datasets. However, preparing such massive dataset is demanding. In this context, Generative Adversarial Networks (GANs) can…

Image and Video Processing · Electrical Eng. & Systems 2021-06-04 Changhee Han

Human anatomy, morphology, and associated diseases can be studied using medical imaging data. However, access to medical imaging data is restricted by governance and privacy concerns, data ownership, and the cost of acquisition, thus…

Despite technological and medical advances, the detection, interpretation, and treatment of cancer based on imaging data continue to pose significant challenges. These include inter-observer variability, class imbalance, dataset shifts,…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Richard Osuala , Kaisar Kushibar , Lidia Garrucho , Akis Linardos , Zuzanna Szafranowska , Stefan Klein , Ben Glocker , Oliver Diaz , Karim Lekadir

AI-assisted imaging made substantial advances in tumor diagnosis and management. However, a major barrier to developing robust oncology foundation models is the scarcity of large-scale, high-quality annotated datasets, which are limited by…

Automated synthesis of histology images has several potential applications in computational pathology. However, no existing method can generate realistic tissue images with a bespoke cellular layout or user-defined histology parameters. In…

Image and Video Processing · Electrical Eng. & Systems 2022-12-29 Srijay Deshpande , Muhammad Dawood , Fayyaz Minhas , Nasir Rajpoot

Synthetic generation of three-dimensional cell models from histopathological images aims to enhance understanding of cell mutation, and progression of cancer, necessary for clinical assessment and optimal treatment. Classical reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2021-02-09 Yoav Alon , Xiang Yu , Huiyu Zhou

Incorporating artificial intelligence (AI) into digital pathology offers promising prospects for automating and enhancing tasks such as image analysis and diagnostic processes. However, the diversity of tissue samples and the necessity for…

Image and Video Processing · Electrical Eng. & Systems 2024-12-04 Nati Daniel , May Nathan , Eden Azeroual , Yael Fisher , Yonatan Savir

Generative modelling and synthetic data can be a surrogate for real medical imaging datasets, whose scarcity and difficulty to share can be a nuisance when delivering accurate deep learning models for healthcare applications. In recent…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Virginia Fernandez , Walter Hugo Lopez Pinaya , Pedro Borges , Mark S. Graham , Tom Vercauteren , M. Jorge Cardoso

Pathology image segmentation across multiple centers encounters significant challenges due to diverse sources of heterogeneity including imaging modalities, organs, and scanning equipment, whose variability brings representation bias and…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Yuan Zhang , Feng Chen , Yaolei Qi , Guanyu Yang , Huazhu Fu

In this paper, we propose a multi-stage and high-resolution model for image synthesis that uses fine-grained attributes and masks as input. With a fine-grained attribute, the proposed model can detailedly constrain the features of the…

Computer Vision and Pattern Recognition · Computer Science 2021-01-13 Pengyang Li , Donghui Wang

Supervised training of an automated medical image analysis system often requires a large amount of expert annotations that are hard to collect. Moreover, the proportions of data available across different classes may be highly imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yuan Xue , Jiarong Ye , Rodney Long , Sameer Antani , Zhiyun Xue , Xiaolei Huang

Biphasic face photo-sketch synthesis has significant practical value in wide-ranging fields such as digital entertainment and law enforcement. Previous approaches directly generate the photo-sketch in a global view, they always suffer from…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Xingqun Qi , Muyi Sun , Zijian Wang , Jiaming Liu , Qi Li , Fang Zhao , Shanghang Zhang , Caifeng Shan

Text-conditioned generative models for volumetric medical imaging provide semantic control but lack explicit anatomical guidance, often resulting in outputs that are spatially ambiguous or anatomically inconsistent. In contrast,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Daniele Molino , Camillo Maria Caruso , Paolo Soda , Valerio Guarrasi

In semantic image synthesis the state of the art is dominated by methods that use customized variants of the SPatially-Adaptive DE-normalization (SPADE) layers, which allow for good visual generation quality and editing versatility. By…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Tomaso Fontanini , Claudio Ferrari , Giuseppe Lisanti , Massimo Bertozzi , Andrea Prati