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This paper presents a comprehensive systematic review of generative models (GANs, VAEs, DMs, and LLMs) used to synthesize various medical data types, including imaging (dermoscopic, mammographic, ultrasound, CT, MRI, and X-ray), text,…

Recent advances in artificial intelligence (AI), in particular self-supervised learning of foundation models (FMs), are revolutionizing medical imaging and computational pathology (CPath). A constant challenge in the analysis of digital…

With the availability of powerful text-to-image diffusion models, recent works have explored the use of synthetic data to improve image classification performances. These works show that it can effectively augment or even replace real data.…

Computer Vision and Pattern Recognition · Computer Science 2023-11-29 Perla Doubinsky , Nicolas Audebert , Michel Crucianu , Hervé Le Borgne

Corneal diseases are the most common eye disorders. Deep learning techniques are used to per-form automated diagnoses of cornea. Deep learning networks require large-scale annotated datasets, which is conceded as a weakness of deep…

Image and Video Processing · Electrical Eng. & Systems 2023-01-30 Samer Kais Jameel , Sezgin Aydin , Nebras H. Ghaeb , Jafar Majidpour , Tarik A. Rashid , Sinan Q. Salih , P. S. JosephNg

Understanding how cellular morphology, gene expression, and spatial context jointly shape tissue function is a central challenge in biology. Image-based spatial transcriptomics technologies now provide high-resolution measurements of cell…

Quantitative Methods · Quantitative Biology 2026-02-17 Zhenglun Kong , Mufan Qiu , John Boesen , Xiang Lin , Sukwon Yun , Tianlong Chen , Manolis Kellis , Marinka Zitnik

Large Language Models (LLMs) have demonstrated strong performance in open-ended generation tasks. However, they often struggle to adapt content to users with differing cognitive capacities, leading to a phenomenon we term cognitive…

Computation and Language · Computer Science 2025-09-25 Qingsong Wang , Tao Wu , Wang Lin , Yueying Feng , Gongsheng Yuan , Chang Yao , Jingyuan Chen

Scarcity of annotated data, particularly for rare or atypical morphologies, present significant challenges for cell and nuclei segmentation in computational pathology. While manual annotation is labor-intensive and costly, synthetic data…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Dominik Winter , Mai Bui , Monica Azqueta Gavaldon , Nicolas Triltsch , Marco Rosati , Nicolas Brieu

With the remarkable recent progress on learning deep generative models, it becomes increasingly interesting to develop models for controllable image synthesis from reconfigurable inputs. This paper focuses on a recent emerged task,…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Wei Sun , Tianfu Wu

We propose a novel cost aggregation network, called Cost Aggregation Transformers (CATs), to find dense correspondences between semantically similar images with additional challenges posed by large intra-class appearance and geometric…

Computer Vision and Pattern Recognition · Computer Science 2021-12-16 Seokju Cho , Sunghwan Hong , Sangryul Jeon , Yunsung Lee , Kwanghoon Sohn , Seungryong Kim

We present GraPLUS (Graph-based Placement Using Semantics), a novel framework for plausible object placement in images that leverages scene graphs and large language models. Our approach uniquely combines graph-structured scene…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Mir Mohammad Khaleghi , Mehran Safayani , Abdolreza Mirzaei

Healthcare artificial intelligence systems often degrade in performance when deployed across institutions, with documented performance drops and perpetuation of discriminatory patterns embedded in data. This brittleness comes, in part, from…

Machine Learning · Computer Science 2026-03-30 Munib Mesinovic , Max Buhlan , Tingting Zhu

Skin cancer is one of the most common cancers worldwide and early detection is critical for effective treatment. However, current AI diagnostic tools are often trained on datasets dominated by lighter skin tones, leading to reduced accuracy…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Areez Muhammed Shabu , Mohammad Samar Ansari , Asra Aslam

This paper presents a novel method to deal with the challenging task of generating photographic images conditioned on semantic image descriptions. Our method introduces accompanying hierarchical-nested adversarial objectives inside the…

Computer Vision and Pattern Recognition · Computer Science 2018-04-10 Zizhao Zhang , Yuanpu Xie , Lin Yang

Artificial intelligence (AI) is transforming cancer diagnosis and treatment. The intricate nature of this disease necessitates the collaboration of diverse stakeholders with varied expertise to ensure the effectiveness of cancer research.…

Digital Libraries · Computer Science 2025-12-30 Shahab Mosallaie , Andrea Schiffauerova , Ashkan Ebadi

One of the most challenging aspects of medical image analysis is the lack of a high quantity of annotated data. This makes it difficult for deep learning algorithms to perform well due to a lack of variations in the input space. While…

Computer Vision and Pattern Recognition · Computer Science 2020-03-13 Soumyajyoti Dey , Soham Das , Swarnendu Ghosh , Shyamali Mitra , Sukanta Chakrabarty , Nibaran Das

We present a novel framework for multi-domain synthesis of artwork from semantic layouts. One of the main limitations of this challenging task is the lack of publicly available segmentation datasets for art synthesis. To address this…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Yuantian Huang , Satoshi Iizuka , Edgar Simo-Serra , Kazuhiro Fukui

Developing reliable healthcare AI models requires training with representative and diverse data. In imbalanced datasets, model performance tends to plateau on the more prevalent classes while remaining low on less common cases. To overcome…

In the realm of dermatological diagnoses, where the analysis of dermatoscopic and microscopic skin lesion images is pivotal for the accurate and early detection of various medical conditions, the costs associated with creating diverse and…

In computer-assisted surgery, automatically recognizing anatomical organs is crucial for understanding the surgical scene and providing intraoperative assistance. While machine learning models can identify such structures, their deployment…

Computer Vision and Pattern Recognition · Computer Science 2024-11-22 Danush Kumar Venkatesh , Dominik Rivoir , Micha Pfeiffer , Fiona Kolbinger , Stefanie Speidel

Computational analysis of whole slide images (WSIs) has seen significant research progress in recent years, with applications ranging across important diagnostic and prognostic tasks such as survival or cancer subtype prediction. Many…

Computer Vision and Pattern Recognition · Computer Science 2024-11-28 Zak Buzzard , Konstantin Hemker , Nikola Simidjievski , Mateja Jamnik
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