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Electronic health records represent a holistic overview of patients' trajectories. Their increasing availability has fueled new hopes to leverage them and develop accurate risk prediction models for a wide range of diseases. Given the…

With COVID-19 now pervasive, identification of high-risk individuals is crucial. Using data from a major healthcare provider in Southwestern Pennsylvania, we develop survival models predicting severe COVID-19 progression. In this endeavor,…

Machine Learning · Computer Science 2022-08-30 Helen Zhou , Cheng Cheng , Kelly J. Shields , Gursimran Kochhar , Tariq Cheema , Zachary C. Lipton , Jeremy C. Weiss

Understanding when and how linguistic knowledge emerges during language model training remains a central challenge for interpretability. Most existing tools are post hoc, rely on scalar metrics, or require nontrivial integration effort,…

Computation and Language · Computer Science 2025-07-08 Nura Aljaafari , Danilo S. Carvalho , André Freitas

Estimating individualized treatment rules (ITRs) is fundamental to precision medicine, where the goal is to tailor treatment decisions to individual patient characteristics. While numerous methods have been developed for ITR estimation,…

Methodology · Statistics 2026-05-15 Eun Jeong Oh , Min Qian

Pandemic outbreaks such as COVID-19 occur unexpectedly, and need immediate action due to their potential devastating consequences on global health. Point-of-care routine assessments such as electrocardiogram (ECG), can be used to develop…

Signal Processing · Electrical Eng. & Systems 2023-01-12 Weijie Sun , Sunil Vasu Kalmady , Nariman Sepehrvand , Luan Manh Chu , Zihan Wang , Amir Salimi , Abram Hindle , Russell Greiner , Padma Kaul

Estimation of temporal counterfactual outcomes from observed history is crucial for decision-making in many domains such as healthcare and e-commerce, particularly when randomized controlled trials (RCTs) suffer from high cost or…

Machine Learning · Computer Science 2024-02-13 Chuizheng Meng , Yihe Dong , Sercan Ö. Arık , Yan Liu , Tomas Pfister

The recent COVID-19 pandemic has promoted vigorous scientific activity in an effort to understand, advice and control the pandemic. Data is now freely available at a staggering rate worldwide. Unfortunately, this unprecedented level of…

Applications · Statistics 2024-01-31 Yuansan Liu , Saransh Srivastava , Zuo Huang , Felisa J. Vázquez-Abad

Deep learning models have shown tremendous potential in learning representations, which are able to capture some key properties of the data. This makes them great candidates for transfer learning: Exploiting commonalities between different…

Annotating medical images for disease detection is often tedious and expensive. Moreover, the available training samples for a given task are generally scarce and imbalanced. These conditions are not conducive for learning effective deep…

Image and Video Processing · Electrical Eng. & Systems 2023-01-24 Fouzia Altaf , Syed M. S. Islam , Naeem K. Janjua , Naveed Akhtar

We address the problem of predicting when a disease will develop, i.e., medical event time (MET), from a patient's electronic health record (EHR). The MET of non-communicable diseases like diabetes is highly correlated to cumulative health…

Machine Learning · Computer Science 2023-06-01 Takayuki Katsuki , Kohei Miyaguchi , Akira Koseki , Toshiya Iwamori , Ryosuke Yanagiya , Atsushi Suzuki

Modern systems (e.g., deep neural networks, big data analytics, and compilers) are highly configurable, which means they expose different performance behavior under different configurations. The fundamental challenge is that one cannot…

Artificial Intelligence · Computer Science 2019-02-27 Mohammad Ali Javidian , Pooyan Jamshidi , Marco Valtorta

We present a Transfer Causal Learning (TCL) framework when target and source domains share the same covariate/feature spaces, aiming to improve causal effect estimation accuracy in limited data. Limited data is very common in medical…

Machine Learning · Computer Science 2024-01-02 Song Wei , Hanyu Zhang , Ronald Moore , Rishikesan Kamaleswaran , Yao Xie

Continual learning aims to update models under distribution shift without forgetting, yet many high-stakes deployments, such as healthcare, also require interpretability. In practice, models that adapt well (e.g., deep networks) are often…

Machine Learning · Computer Science 2026-04-21 Dongkyu Cho , Xiyue Li , Samrachana Adhikari , Rumi Chunara

The COVID-19 pandemic has magnified an already existing trend of people looking for healthcare solutions online. One class of solutions are symptom checkers, which have become very popular in the context of COVID-19. Traditional symptom…

Artificial Intelligence · Computer Science 2020-12-02 Anitha Kannan , Richard Chen , Vignesh Venkataraman , Geoffrey J. Tso , Xavier Amatriain

Dynamic treatment regimes (DTRs) are critical to precision medicine, optimizing long-term outcomes through personalized, real-time decision-making in evolving clinical contexts, but require careful supervision for unsafe treatment risks.…

Machine Learning · Computer Science 2025-06-10 Yishan Shen , Yuyang Ye , Hui Xiong , Yong Chen

Predicting pedestrian motion trajectories is crucial for path planning and motion control of autonomous vehicles. Accurately forecasting crowd trajectories is challenging due to the uncertain nature of human motions in different…

Computer Vision and Pattern Recognition · Computer Science 2024-01-11 Yu Liu , Yuexin Zhang , Kunming Li , Yongliang Qiao , Stewart Worrall , You-Fu Li , He Kong

In order to model the evolution of user preference, we should learn user/item embeddings based on time-ordered item purchasing sequences, which is defined as Sequential Recommendation (SR) problem. Existing methods leverage sequential…

Information Retrieval · Computer Science 2021-08-24 Ziwei Fan , Zhiwei Liu , Jiawei Zhang , Yun Xiong , Lei Zheng , Philip S. Yu

The impact of machine learning models on healthcare will depend on the degree of trust that healthcare professionals place in the predictions made by these models. In this paper, we present a method to provide people with clinical expertise…

Machine Learning · Computer Science 2021-03-05 Aniruddh Raghu , John Guttag , Katherine Young , Eugene Pomerantsev , Adrian V. Dalca , Collin M. Stultz

Clinical outcome prediction based on the Electronic Health Record (EHR) plays a crucial role in improving the quality of healthcare. Conventional deep sequential models fail to capture the rich temporal patterns encoded in the longand…

Machine Learning · Computer Science 2019-08-27 Luchen Liu , Haoran Li , Zhiting Hu , Haoran Shi , Zichang Wang , Jian Tang , Ming Zhang

Generalizing deep reinforcement learning agents to unseen environments remains a significant challenge. One promising solution is Unsupervised Environment Design (UED), a co-evolutionary framework in which a teacher adaptively generates…

Machine Learning · Computer Science 2026-03-17 Geonwoo Cho , Jaegyun Im , Jihwan Lee , Hojun Yi , Sejin Kim , Sundong Kim
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