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Tip enhanced Raman scattering (TERS) amplifies the intensity of vibrational Raman scattering by employing the tip of a probe interacting, in ultra close proximity, with a surface. Although a general understanding of the TERS process is…

Dynamic surface-enhanced Raman spectroscopy (SERS) is nowadays one of the most interesting applications of SERS, in particular for single molecule studies. In fact, it enables the study of real-time processes at the molecular level. This…

Creating plasmonic nanoparticles on a tapered optical fiber tip enables a remote SERS sensing probe, ideal for challenging sampling scenarios like biological tissue, specific cells, on-site environmental monitoring, and deep brain…

Synthesis and characterization of high-quality single-crystal WSe2 films on highly-insulating substrate is presented. We demonstrate for the first time that the presence of gold nanoparticles in the basal plane of a WSe2 film can enhance…

Mesoscale and Nanoscale Physics · Physics 2018-11-21 Bablu Mukherjee , Wei Sun Leong , Yida Li , Hao Gong , Linfeng Sun , Ze Xiang Shen , Ergun Simsek , John T. L. Thong

In the case of polymer medical devices, the surface design plays a crucial role in contact with human tissue. The use of AgNPs as antibacterial agents is well known; however, their anchoring into the polymer surface can still be…

Other Quantitative Biology · Quantitative Biology 2023-12-06 Jana Pryjmakova , Daniel Grossberger , Anna Kutova , Barbora Vokata , Miroslav Slouf , Petr Slepicka , Jakub Siegel

There is an urgent need for the development of novel and truly rapid (equal or less than 1 hour) antibiotic susceptibility testing (AST) platforms in order to provide best antimicrobial prescribing practices and to help reduce the…

Subcellular Processes · Quantitative Biology 2025-01-22 Allen Fraiman , Lawrence Ziegler

We demonstrated fabrication of black silicon with slanted nanocone array on both planar and 3D micro and meso scale structures produced by a high-throughput lithography-free oblique-angle plasma etching process. Nanocones with gradual…

Mesoscale and Nanoscale Physics · Physics 2014-02-10 Zhida Xu , Logan Liu

Tip-Enhanced Raman Spectroscopy (TERS) provides nanoscale chemical fingerprints alongside high-resolution topographic mapping of molecules, offering a powerful tool for materials discovery. However, TERS image datasets are challenging to…

Materials Science · Physics 2026-02-24 Harshit Sethi , Markus Junttila , Orlando J Silveira , Adam S Foster

Ordered Ag nanowire arrays with high aspect ratio and high density self-supporting Ag nanowire patterns were successfully prepared using potentiostatic electrodeposition within the confined nanochannels of a commercial porous anodic…

Materials Science · Physics 2011-06-15 Baoliang Sun , Xiaohong Jiang , Shuxi Dai , Zuliang Du

Single molecule detection, sequencing and conformational mapping of aptamers are important for improving medical and biosensing technologies and for better understanding of biological processes at the molecular level. We obtain vibrational…

Biomolecules · Quantitative Biology 2016-12-05 Siyu He , Hongyuan Li , Zhe He , Dmitri V. Voronine

We present a general framework for inverse design of nanopatterned surfaces that maximize spatially averaged surface-enhanced Raman (SERS) spectra from molecules distributed randomly throughout a material or fluid, building upon a recently…

Topology optimization (TO) of 3D surface-enhanced Raman scattering (SERS) substrates faces challenges in managing field singularities and modeling orientation-averaged anisotropic molecules. We present 3D TO for manufacturable SERS…

An early detection of different tumor subtypes is crucial for an effective guidance to personalized therapy. While much efforts focus on decoding the sequence of DNA basis to detect the genetic mutations related to cancer, it is becoming…

Surface-Enhanced Raman Scattering (SERS) allows for detection and identification of molecular vibrational fingerprints in minute sample quantities. The SERS process can be also exploited for optical manipulation of molecular vibrations. We…

Optical fiber-based platforms are increasingly explored as compact, minimally invasive tools for integrated photonic functionalities in biomedical applications. Among these, the combination of plasmonic heating and optical sensing on a…

Surface Enhanced Raman Spectroscopy (SERS) is a highly sensitive and selective technique that greatly enhances the signal of an analyte, compared with its signal from classical Raman Spectroscopy, due to its interaction with a substrates…

Materials Science · Physics 2025-10-20 Jan Komeda , Antonio Cammarata , Tomas Polcar

This comprehensive review discusses the development of scanning electron microscopy and the application of this technology in different fields such as biology, nanobiotechnology and biomedical science. Besides being a tool for high…

Quantitative Methods · Quantitative Biology 2023-11-02 Aniruddha Acharya

Raman spectroscopy is a powerful technique to characterize materials. It probes non-destructively chemical composition, crystallinity, defects, strain and coupling phenomena. However, the Raman response of surfaces or thin films is often…

It is an established understanding that the electromagnetic contribution (the plasmon-mediated enhancement of the laser and scattered local electromagnetic fields) is the main actor in Surface Enhanced Raman Scattering (SERS), with the…

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