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Chromatin sensitive partial wave spectroscopic (csPWS) microscopy enables label free detection of nanoscale chromatin packing alterations that occur before visible cellular transformation. However, manual nuclear segmentation limits…

Image and Video Processing · Electrical Eng. & Systems 2025-10-28 Jahidul Arafat , Sanjaya Poudel

t-SNE and hierarchical clustering are popular methods of exploratory data analysis, particularly in biology. Building on recent advances in speeding up t-SNE and obtaining finer-grained structure, we combine the two to create tree-SNE, a…

Machine Learning · Computer Science 2020-02-14 Isaac Robinson , Emma Pierce-Hoffman

Detecting synaptic clefts is a crucial step to investigate the biological function of synapses. The volume electron microscopy (EM) allows the identification of synaptic clefts by photoing EM images with high resolution and fine details.…

Computer Vision and Pattern Recognition · Computer Science 2021-01-13 Yi Liu , Shuiwang Ji

In the realm of modern diagnostic technology, video capsule endoscopy (VCE) is a standout for its high efficacy and non-invasive nature in diagnosing various gastrointestinal (GI) conditions, including obscure bleeding. Importantly, for the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Hechen Li , Yanan Wu , Long Bai , An Wang , Tong Chen , Hongliang Ren

Recently, the lung infection due to Coronavirus Disease (COVID-19) affected a large human group worldwide and the assessment of the infection rate in the lung is essential for treatment planning. This research aims to propose a…

Image and Video Processing · Electrical Eng. & Systems 2020-04-29 Seifedine Kadry , Venkatesan Rajinikanth , Seungmin Rho , Nadaradjane Sri Madhava Raja , Vaddi Seshagiri Rao , Krishnan Palani Thanaraj

Segmentation of histological images is one of the most crucial tasks for many biomedical analyses including quantification of certain tissue type. However, challenges are posed by high variability and complexity of structural features in…

Computer Vision and Pattern Recognition · Computer Science 2020-07-30 Xiaohang Fu , Tong Liu , Zhaohan Xiong , Bruce H. Smaill , Martin K. Stiles , Jichao Zhao

Pelvic fractures, often caused by high-impact trauma, frequently require surgical intervention. Imaging techniques such as CT and 2D X-ray imaging are used to transfer the surgical plan to the operating room through image registration,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Daiqi Liu , Fuxin Fan , Andreas Maier

Many medical and biological protocols for analyzing individual biological cells involve morphological evaluation based on cell staining, designed to enhance imaging contrast and enable clinicians and biologists to differentiate between…

Lung cancer is a primary contributor to cancer-related mortality globally, highlighting the necessity for precise early detection of pulmonary nodules through low-dose CT (LDCT) imaging. Deep learning methods have improved nodule detection…

Quantitative Methods · Quantitative Biology 2025-12-10 Fateme Mobini , Mohammad Reza Hedyehzadeh , Mahdi Yousefi

Self-supervised learning (SSL) methods are popular since they can address situations with limited annotated data by directly utilising the underlying data distribution. However, the adoption of such methods is not explored enough in…

Image and Video Processing · Electrical Eng. & Systems 2024-08-01 Joseph Geo Benjamin , Mothilal Asokan , Amna Alhosani , Hussain Alasmawi , Werner Gerhard Diehl , Leanne Bricker , Karthik Nandakumar , Mohammad Yaqub

Efficient label acquisition processes are key to obtaining robust classifiers. However, data labeling is often challenging and subject to high levels of label noise. This can arise even when classification targets are well defined, if…

Artificial Intelligence · Computer Science 2018-08-22 Olivier Deiss , Siddharth Biswal , Jing Jin , Haoqi Sun , M. Brandon Westover , Jimeng Sun

Automated fetal brain extraction from full-uterus MRI is a challenging task due to variable head sizes, orientations, complex anatomy, and prevalent artifacts. While deep-learning (DL) models trained on synthetic images have been successful…

Image and Video Processing · Electrical Eng. & Systems 2024-10-30 Javid Dadashkarimi , Valeria Pena Trujillo , Camilo Jaimes , Lilla Zöllei , Malte Hoffmann

Segmentation of medical images is a fundamental task with numerous applications. While MRI, CT, and PET modalities have significantly benefited from deep learning segmentation techniques, more recent modalities, like functional ultrasound…

Image and Video Processing · Electrical Eng. & Systems 2025-07-24 Hana Sebia , Thomas Guyet , Mickaël Pereira , Marco Valdebenito , Hugues Berry , Benjamin Vidal

Motivation: Capillary electrophoresis (CE) of nucleic acids is a workhorse technology underlying high-throughput genome analysis and large-scale chemical mapping for nucleic acid structural inference. Despite the wide availability of…

Quantitative Methods · Quantitative Biology 2011-05-16 Sungroh Yoon , Jinkyu Kim , Justine Hum , Hanjoo Kim , Seunghyun Park , Wipapat Kladwang , Rhiju Das

Bright-field microscopy, a cost-effective solution for live-cell culture, is often the only resource available, along with standard CPUs, for many low-budget labs. The inherent challenges of bright-field images -- their noisiness, low…

Quantitative Methods · Quantitative Biology 2025-11-03 Surajit Das , Pavel Zun

Surgical phase segmentation is central to computer-assisted surgery, yet robust models remain difficult to develop when labeled surgical videos are scarce. We study data-efficient phase segmentation for manual small-incision cataract…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Lincoln Spencer , Song Wang , Chen Chen

In the last two decades Computer Aided Diagnostics (CAD) systems were developed to help radiologists analyze screening mammograms. The benefits of current CAD technologies appear to be contradictory and they should be improved to be…

Computer Vision and Pattern Recognition · Computer Science 2017-11-10 Dezső Ribli , Anna Horváth , Zsuzsa Unger , Péter Pollner , István Csabai

Sickle cell anemia, which is characterized by abnormal erythrocyte morphology, can be detected using microscopic images. Computational techniques in medicine enhance the diagnosis and treatment efficiency. However, many computational…

Computer Vision and Pattern Recognition · Computer Science 2024-12-25 Victor Júnio Alcântara Cardoso , Rodrigo Moreira , João Fernando Mari , Larissa Ferreira Rodrigues Moreira

Tissue stiffness is related to soft tissue pathologies and can be assessed through palpation or via clinical imaging systems, e.g., ultrasound or magnetic resonance imaging. Typically, the image based approaches are not suitable during…

Signal Processing · Electrical Eng. & Systems 2025-09-04 Maximilian Neidhardt , Sarah Latus , Tim Eixmann , Gereon Hüttmann , Alexander Schlaefer

Accurate click-through rate (CTR) prediction is vital for online advertising and recommendation systems. Recent deep learning advancements have improved the ability to capture feature interactions and understand user interests. However,…

Information Retrieval · Computer Science 2025-02-24 Kefan Wang , Hao Wang , Kenan Song , Wei Guo , Kai Cheng , Zhi Li , Yong Liu , Defu Lian , Enhong Chen