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We propose an unsupervised deep learning method for atlas based registration to achieve segmentation and spatial alignment of the embryonic brain in a single framework. Our approach consists of two sequential networks with a specifically…

Image and Video Processing · Electrical Eng. & Systems 2020-05-14 Wietske A. P. Bastiaansen , Melek Rousian , Régine P. M. Steegers-Theunissen , Wiro J. Niessen , Anton Koning , Stefan Klein

We propose a clustering-based approach for identifying coherent flow structures in continuous dynamical systems. We first treat a particle trajectory over a finite time interval as a high-dimensional data point and then cluster these data…

Dynamical Systems · Mathematics 2022-12-27 Wai Ming Chau , Shingyu Leung

Cervical intraepithelial neoplasia (CIN) grade of histopathology images is a crucial indicator in cervical biopsy results. Accurate CIN grading of epithelium regions helps pathologists with precancerous lesion diagnosis and treatment…

Image and Video Processing · Electrical Eng. & Systems 2019-07-26 Yuan Xue , Qianying Zhou , Jiarong Ye , L. Rodney Long , Sameer Antani , Carl Cornwell , Zhiyun Xue , Xiaolei Huang

Studying the cellular architecture of the human cerebral cortex is critical for understanding brain organization and function. It requires investigating complex texture patterns in histological images, yet automatic methods that scale…

Neurons and Cognition · Quantitative Biology 2026-03-06 Christian Schiffer , Zeynep Boztoprak , Jan-Oliver Kropp , Julia Thönnißen , Katia Berr , Hannah Spitzer , Katrin Amunts , Timo Dickscheid

Carotid atherosclerosis is the major cause of ischemic stroke resulting in significant rates of mortality and disability annually. Early diagnosis of such cases is of great importance, since it enables clinicians to apply a more effective…

Image and Video Processing · Electrical Eng. & Systems 2022-02-08 Theofanis Ganitidis , Maria Athanasiou , Kalliopi Dalakleidi , Nikos Melanitis , Spyretta Golemati , Konstantina S Nikita

Medical image classification has developed rapidly under the impetus of the convolutional neural network (CNN). Due to the fixed size of the receptive field of the convolution kernel, it is difficult to capture the global features of…

Image and Video Processing · Electrical Eng. & Systems 2022-09-22 Xiangzuo Huo , Gang Sun , Shengwei Tian , Yan Wang , Long Yu , Jun Long , Wendong Zhang , Aolun Li

Semantic segmentation of breast cancer metastases in histopathological slides is a challenging task. In fact, significant variation in data characteristics of histopathology images (domain shift) make generalization of deep learning to…

Image and Video Processing · Electrical Eng. & Systems 2021-06-01 Gianluca Gerard , Marco Piastra

Confocal laser endomicroscopy (CLE) is a non-invasive, real-time imaging modality that can be used for in-situ, in-vivo imaging and the microstructural analysis of mucous structures. The diagnosis using CLE is, however, complicated by…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Nils Porsche , Flurin Müller-Diesing , Sweta Banerjee , Miguel Goncalves , Marc Aubreville

The click-through rate (CTR) prediction task is to predict whether a user will click on the recommended item. As mind-boggling amounts of data are produced online daily, accelerating CTR prediction model training is critical to ensuring an…

Minimally invasive image-guided surgery heavily relies on vision. Deep learning models for surgical video analysis could therefore support visual tasks such as assessing the critical view of safety (CVS) in laparoscopic cholecystectomy…

Image and Video Processing · Electrical Eng. & Systems 2021-09-21 Pietro Mascagni , Deepak Alapatt , Alain Garcia , Nariaki Okamoto , Armine Vardazaryan , Guido Costamagna , Bernard Dallemagne , Nicolas Padoy

Label-free approaches are attractive in cytological imaging due to their flexibility and cost efficiency. They are supported by machine learning methods, which, despite the lack of labeling and the associated lower contrast, can classify…

Computer Vision and Pattern Recognition · Computer Science 2023-11-27 Stefan Röhrl , Johannes Groll , Manuel Lengl , Simon Schumann , Christian Klenk , Dominik Heim , Martin Knopp , Oliver Hayden , Klaus Diepold

Failure in brittle materials under dynamic loading conditions is a result of the propagation and coalescence of microcracks. Simulating this mechanism at the continuum level is computationally expensive or, in some cases, intractable. The…

Deep learning segmentation and fluorescence imaging techniques allow the cellular morphology of living embryos to be constructed spatiotemporally. These development processes involve numerous molecules distributed at the subcellular scale,…

This paper investigates the application of deep learning models for lung Computed Tomography (CT) image analysis. Traditional deep learning frameworks encounter compatibility issues due to variations in slice numbers and resolutions in CT…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Chih-Chung Hsu , Chih-Yu Jian , Chia-Ming Lee , Chi-Han Tsai , Sheng-Chieh Dai

Nowadays, computer-aided sperm analysis (CASA) systems have made a big leap in extracting the characteristics of spermatozoa for studies or measuring human fertility. The first step in sperm characteristics analysis is sperm detection in…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Mohammad reza Mohammadi , Mohammad Rahimzadeh , Abolfazl Attar

A manual assessment of sperm motility requires microscopy observation, which is challenging due to the fast-moving spermatozoa in the field of view. To obtain correct results, manual evaluation requires extensive training. Therefore,…

The usage of chemical imaging technologies is becoming a routine accompaniment to traditional methods in pathology. Significant technological advances have developed these next generation techniques to provide rich, spatially resolved,…

Machine Learning · Computer Science 2022-09-07 Spencer A. Thomas

Screening Papanicolaou test samples has proven to be highly effective in reducing cervical cancer-related mortality. However, the lack of trained cytopathologists hinders its widespread implementation in low-resource settings. Deep…

Image and Video Processing · Electrical Eng. & Systems 2023-06-08 Thomas Stegmüller , Christian Abbet , Behzad Bozorgtabar , Holly Clarke , Patrick Petignat , Pierre Vassilakos , Jean-Philippe Thiran

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

Cytoarchitectonic mapping provides anatomically grounded parcellations of brain structure and forms a foundation for integrative, multi-modal neuroscience analyses. These parcellations are defined based on the shape, density, and spatial…

Image and Video Processing · Electrical Eng. & Systems 2026-01-16 Shiqi Zhang , Fang Xu , Pengcheng Zhou
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