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In conventional clinical in-vitro fertilization practices embryos are transferred either at the cleavage or blastocyst stages of development. Cleavage stage transfers, particularly, are beneficial for patients with relatively poor prognosis…

Infertility has a considerable impact on individuals' quality of life, affecting them socially and psychologically, with projections indicating a rise in the upcoming years. In vitro fertilization (IVF) emerges as one of the primary…

A major challenge in clinical In-Vitro Fertilization (IVF) is selecting the highest quality embryo to transfer to the patient in the hopes of achieving a pregnancy. Time-lapse microscopy provides clinicians with a wealth of information for…

Embryo quality assessment after in vitro fertilization (IVF) is primarily done visually by embryologists. Variability among assessors, however, remains one of the main causes of the low success rate of IVF. This study aims to develop an…

Image and Video Processing · Electrical Eng. & Systems 2020-08-31 Ali Akbar Septiandri , Ade Jamal , Pritta Ameilia Iffanolida , Oki Riayati , Budi Wiweko

Artificial intelligence has recently shown promise in automated embryo selection for In-Vitro Fertilization (IVF). However, current approaches either address partial embryo evaluation lacking holistic quality assessment or target clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Yong Sun , Yipeng Wang , Junyu Shi , Zhiyuan Zhang , Yanmei Xiao , Lei Zhu , Manxi Jiang , Qiang Nie

Time-lapse is a technology used to record the development of embryos during in-vitro fertilization (IVF). Accurate classification of embryo early development stages can provide embryologists valuable information for assessing the embryo…

Image and Video Processing · Electrical Eng. & Systems 2019-08-27 Zihan Liu , Bo Huang , Yuqi Cui , Yifan Xu , Bo Zhang , Lixia Zhu , Yang Wang , Lei Jin , Dongrui Wu

The selection of the optimal embryo for transfer is a critical yet challenging step in in vitro fertilization (IVF), primarily due to its reliance on the manual inspection of extensive time-lapse imaging data. A key obstacle in this process…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Zahra Asghari Varzaneh , Niclas Wölner-Hanssen , Reza Khoshkangini , Thomas Ebner , Magnus Johnsson

Automating human preimplantation embryo grading offers the potential for higher success rates with in vitro fertilization (IVF) by providing new quantitative and objective measures of embryo quality. Current IVF procedures typically use…

Image and Video Processing · Electrical Eng. & Systems 2020-08-21 Md Yousuf Harun , M Arifur Rahman , Joshua Mellinger , Willy Chang , Thomas Huang , Brienne Walker , Kristen Hori , Aaron T. Ohta

The developmental process of embryos follows a monotonic order. An embryo can progressively cleave from one cell to multiple cells and finally transform to morula and blastocyst. For time-lapse videos of embryos, most existing developmental…

Computer Vision and Pattern Recognition · Computer Science 2021-07-15 Stanislav Lukyanenko , Won-Dong Jang , Donglai Wei , Robbert Struyven , Yoon Kim , Brian Leahy , Helen Yang , Alexander Rush , Dalit Ben-Yosef , Daniel Needleman , Hanspeter Pfister

A critical factor that influences the success of an in-vitro fertilization (IVF) procedure is the quality of the transferred embryo. Embryo morphology assessments, conventionally performed through manual microscopic analysis suffer from…

This study addresses the issue of leveraging federated learning to improve data privacy and performance in IVF embryo selection. The EM (Expectation-Maximization) algorithm is incorporated into deep learning models to form a federated…

Image and Video Processing · Electrical Eng. & Systems 2025-01-09 Jung-Hua Wang , Huai-Wen Chang , Rong-Yu Wu , Ting-Yuan Wang , Ming-Jer Chen , Yu-Chiao Yi

We present the first deep learning model for the analysis of intracytoplasmic sperm injection (ICSI) procedures. Using a dataset of ICSI procedure videos, we train a deep neural network to segment key objects in the videos achieving a mean…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Chloe He , Raksha Jain , Jérôme Chambost , Céline Jacques , Cristina Hickman

Segmentation and spatial alignment of ultrasound (US) imaging data acquired in the in first trimester are crucial for monitoring human embryonic growth and development throughout this crucial period of life. Current approaches are either…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 W. A. P. Bastiaansen , M. Rousian , R. P. M. Steegers-Theunissen , W. J. Niessen , A. H. J. Koning , S. Klein

Embryo quality assessment based on morphological attributes is important for achieving higher pregnancy rates from in vitro fertilization (IVF). The accurate segmentation of the embryo's inner cell mass (ICM) and trophectoderm epithelium…

Image and Video Processing · Electrical Eng. & Systems 2020-08-21 Md Yousuf Harun , Thomas Huang , Aaron T. Ohta

Deep learning has achieved spectacular performance in image and speech recognition and synthesis. It outperforms other machine learning algorithms in problems where large amounts of data are available. In the area of measurement technology,…

Quantitative Methods · Quantitative Biology 2019-08-20 Yueqin Li , Ata Mahjoubfar , Claire Lifan Chen , Kayvan Reza Niazi , Li Pei , Bahram Jalali

Reliable evaluation of blastocyst quality is critical for the success of in vitro fertilization (IVF) treatments. Current embryo grading practices primarily rely on visual assessment of morphological features, which introduces subjectivity,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Nahid Khoshk Angabini , Mohsen Tajgardan , Mahesh Madhavan , Zahra Asghari Varzaneh , Reza Khoshkangini , Thomas Ebner

This paper presents a deep learning framework for image classification aimed at increasing predictive performance for Cytotoxic Edema (CE) diagnosis in infants and children. The proposed framework includes two 3D network architectures…

Image and Video Processing · Electrical Eng. & Systems 2022-10-11 Henok Ghebrechristos , Stence Nicholas , David Mirsky , Gita Alaghband , Manh Huynh , Zackary Kromer , Ligia Batista , Brent ONeill , Steven Moulton , Daniel M. Lindberg

Assessing and selecting the most viable embryos for transfer is an essential part of in vitro fertilization (IVF). In recent years, several approaches have been made to improve and automate the procedure using artificial intelligence (AI)…

Machine Learning · Computer Science 2022-04-06 Jørgen Berntsen , Jens Rimestad , Jacob Theilgaard Lassen , Dang Tran , Mikkel Fly Kragh

In clinical In-Vitro Fertilization (IVF), identifying the most viable embryo for transfer is important to increasing the likelihood of a successful pregnancy. Traditionally, this process involves embryologists manually assessing embryos'…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Junsik Kim , Zhiyi Shi , Davin Jeong , Johannes Knittel , Helen Y. Yang , Yonghyun Song , Wanhua Li , Yicong Li , Dalit Ben-Yosef , Daniel Needleman , Hanspeter Pfister

Automating embryo viability prediction for in vitro fertilization (IVF) is important but challenging due to the limited availability of labeled pregnancy outcome data, as only a small fraction of embryos are labeled after transfer.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Zhiyi Shi , Junsik Kim , Helen Y. Yang , Yonghyun Song , Hyun-Jic Oh , Dalit Ben-Yosef , Daniel Needleman , Hanspeter Pfister
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