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Confocal laser endomicroscopy (CLE) is an advanced optical fluorescence technology undergoing assessment for applications in brain tumor surgery. Despite its promising potential, interpreting the unfamiliar gray tone images of fluorescent…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Mohammadhassan Izadyyazdanabadi , Evgenii Belykh , Michael Mooney , Nikolay Martirosyan , Jennifer Eschbacher , Peter Nakaji , Mark C. Preul , Yezhou Yang

Videomicroscopy, when combined with machine learning, offers a promising approach for studying the early development of in vitro produced (IVP) embryos. However, manually annotating developmental events, and more specifically cell…

Quantitative Methods · Quantitative Biology 2026-05-19 Yasmine Hachani , Patrick Bouthemy , Elisa Fromont , Sylvie Ruffini , Ludivine Laffont , Alline de Paula Reis

The functions of different regions of the human brain are closely linked to their distinct cytoarchitecture, which is defined by the spatial arrangement and morphology of the cells. Identifying brain regions by their cytoarchitecture…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Pralaypati Ta , Sriram Venkatesaperumal , Keerthi Ram , Mohanasankar Sivaprakasam

An important limitation to the development of Artificial Intelligence (AI)-based solutions for In Vitro Fertilization (IVF) is the absence of a public reference benchmark to train and evaluate deep learning (DL) models. In this work, we…

Image and Video Processing · Electrical Eng. & Systems 2022-05-16 Tristan Gomez , Magalie Feyeux , Nicolas Normand , Laurent David , Perrine Paul-Gilloteaux , Thomas Fréour , Harold Mouchère

Cervical Cancer continues to be the leading gynecological malignancy, posing a persistent threat to women's health on a global scale. Early screening via cytology Whole Slide Image (WSI) diagnosis is critical to prevent this Cancer…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Honglin Li , Yusuan Sun , Chenglu Zhu , Yunlong Zhang , Shichuan Zhang , Zhongyi Shui , Pingyi Chen , Jingxiong Li , Sunyi Zheng , Can Cui , Lin Yang

This research aims to develop a dynamic and scalable framework to facilitate harmonization of Common Data Elements (CDEs) across heterogeneous biomedical datasets by addressing challenges such as semantic heterogeneity, structural…

Information Retrieval · Computer Science 2025-06-04 Madan Krishnamurthy , Daniel Korn , Melissa A Haendel , Christopher J Mungall , Anne E Thessen

Cervical cancer is one of the most deadly and common diseases among women worldwide. It is completely curable if diagnosed in an early stage, but the tedious and costly detection procedure makes it unviable to conduct population-wise…

Computer Vision and Pattern Recognition · Computer Science 2021-10-25 Hritam Basak , Rohit Kundu , Sukanta Chakraborty , Nibaran Das

Embryo fragmentation is a morphological indicator critical for evaluating developmental potential in In Vitro Fertilization (IVF). However, manual grading is subjective and inefficient, while existing deep learning solutions often lack…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Ming-Jhe Lee

Cervical cancer remains a significant health challenge, with high incidence and mortality rates, particularly in transitioning countries. Conventional Liquid-Based Cytology(LBC) is a labor-intensive process, requires expert pathologists and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-30 Love Panta , Suraj Prasai , Karishma Malla Vaidya , Shyam Shrestha , Suresh Manandhar

Human brain atlases provide spatial reference systems for data characterizing brain organization at different levels, coming from different brains. Cytoarchitecture is a basic principle of the microstructural organization of the brain, as…

Image and Video Processing · Electrical Eng. & Systems 2021-07-07 Christian Schiffer , Hannah Spitzer , Kai Kiwitz , Nina Unger , Konrad Wagstyl , Alan C. Evans , Stefan Harmeling , Katrin Amunts , Timo Dickscheid

Labelling tissue components in histology whole slide images (WSIs) is prohibitively labour-intensive: a single slide may contain tens of thousands of structures--cells, nuclei, and other morphologically distinct objects--each requiring…

Quantitative Methods · Quantitative Biology 2026-04-13 Muhammad Haseeb Ahmad , Sharmila Rajendran , Damion Young , Jon Mason

Tracking all nuclei of an embryo in noisy and dense fluorescence microscopy data is a challenging task. We build upon a recent method for nuclei tracking that combines weakly-supervised learning from a small set of nuclei center point…

Computer Vision and Pattern Recognition · Computer Science 2022-08-25 Peter Hirsch , Caroline Malin-Mayor , Anthony Santella , Stephan Preibisch , Dagmar Kainmueller , Jan Funke

Accurate embryo morphology assessment is essential in assisted reproductive technology for selecting the most viable embryo. Artificial intelligence has the potential to enhance this process. However, the limited availability of embryo data…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Oriana Presacan , Alexandru Dorobantiu , Vajira Thambawita , Michael A. Riegler , Mette H. Stensen , Mario Iliceto , Alexandru C. Aldea , Akriti Sharma

Automated analysis of volumetric medical imaging on edge devices is severely constrained by the high memory and computational demands of 3D Convolutional Neural Networks (CNNs). This paper develops a lightweight computer vision framework…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Amirreza Parvahan , Mohammad Hoseyni , Javad Khoramdel , Amirhossein Nikoofard

The timing of cell divisions in early embryos during the In-Vitro Fertilization (IVF) process is a key predictor of embryo viability. However, observing cell divisions in Time-Lapse Monitoring (TLM) is a time-consuming process and highly…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Tien-Phat Nguyen , Trong-Thang Pham , Tri Nguyen , Hieu Le , Dung Nguyen , Hau Lam , Phong Nguyen , Jennifer Fowler , Minh-Triet Tran , Ngan Le

Deep learning generally suffers from enormous computational resources and time-consuming training processes. Broad Learning System (BLS) and its convolutional variants have been proposed to mitigate these issues and have achieved superb…

Machine Learning · Computer Science 2023-04-04 Chunyu Lei , C. L. Philip Chen , Jifeng Guo , Tong Zhang

Cervical cancer is one of the most severe diseases threatening women's health. Early detection and diagnosis can significantly reduce cancer risk, in which cervical cytology classification is indispensable. Researchers have recently…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Linyi Qian , Qian Huang , Yulin Chen , Junzhou Chen

Determining cell identities in imaging sequences is an important yet challenging task. The conventional method for cell identification is via cell tracking, which is complex and can be time-consuming. In this study, we propose an innovative…

Quantitative Methods · Quantitative Biology 2024-03-05 Baiyang Dai , Jiamin Yang , Hari Shroff , Patrick La Riviere

Ultrasound is the primary imaging modality in clinical practice during pregnancy. More than 140M fetuses are born yearly, resulting in numerous scans. The availability of a large volume of fetal ultrasound scans presents the opportunity to…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Hussain Alasmawi , Leanne Bricker , Mohammad Yaqub

The process of fertilizing a human egg outside the body in order to help those suffering from infertility to conceive is known as in vitro fertilization (IVF). Despite being the most effective method of assisted reproductive technology…