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The use of multi-centric analyses is crucial for obtaining sufficient sample sizes and representative clinical populations in experimental studies. In this setting, data harmonization techniques are typically employed to address systematic…

Quantitative Methods · Quantitative Biology 2026-01-22 Santiago Silva , Ghiles Reguig , Neil P Oxtoby , Andre Altmann , Marco Lorenzi

Target tracking represents a state estimation problem recurrent in many practical scenarios like air traffic control, autonomous vehicles, marine radar surveillance and so on. In a Bayesian perspective, when phenomena like clutter are…

Applications · Statistics 2022-11-28 Alessandro D'Ortenzio , Costanzo Manes , Umut Orguner

Gaussian Probability Path based Generative Models (GPPGMs) generate data by reversing a stochastic process that progressively corrupts samples with Gaussian noise. Despite state-of-the-art results in 3D molecular generation, their…

Machine Learning · Computer Science 2026-02-23 Jingxiang Qu , Wenhan Gao , Ruichen Xu , Yi Liu

Reliable machine learning and statistical analysis rely on diverse, well-distributed training data. However, real-world datasets are often limited in size and exhibit underrepresentation across key subpopulations, leading to biased…

Methodology · Statistics 2025-07-15 Xinyu Tian , Xiaotong Shen

Finite mixture models are among the most popular statistical models used in different data science disciplines. Despite their broad applicability, inference under these models typically leads to computationally challenging non-convex…

Machine Learning · Computer Science 2018-09-25 Babak Barazandeh , Meisam Razaviyayn

The bat algorithm (BA) has been shown to be effective to solve a wider range of optimization problems. However, there is not much theoretical analysis concerning its convergence and stability. In order to prove the convergence of the bat…

Optimization and Control · Mathematics 2019-03-29 Si Chen , Guo-Hua Peng , Xing-Shi He , Xin-She Yang

Computer models are commonly used to represent a wide range of real systems, but they often involve some unknown parameters. Estimating the parameters by collecting physical data becomes essential in many scientific fields, ranging from…

Applications · Statistics 2020-05-27 Chih-Li Sung , Beau David Barber , Berkley J. Walker

The recent, impressive advances in algorithmic generation of high-fidelity image, audio, and video are largely due to great successes in score-based diffusion models. A key implementing step is score matching, that is, the estimation of the…

Machine Learning · Statistics 2024-09-12 Zehao Dou , Subhodh Kotekal , Zhehao Xu , Harrison H. Zhou

Healthcare relies on multiple types of data, such as medical images, genetic information, and clinical records, to improve diagnosis and treatment. However, missing data is a common challenge due to privacy restrictions, cost, and technical…

Machine Learning · Computer Science 2025-03-13 Nazanin Moradinasab , Saurav Sengupta , Jiebei Liu , Sana Syed , Donald E. Brown

The Expectation-Maximization (EM) algorithm is a widely used method for maximum likelihood estimation in models with latent variables. For estimating mixtures of Gaussians, its iteration can be viewed as a soft version of the k-means…

Machine Learning · Statistics 2017-06-06 Constantinos Daskalakis , Christos Tzamos , Manolis Zampetakis

Algorithmic robust statistics has traditionally focused on the contamination model where a small fraction of the samples are arbitrarily corrupted. We consider a recent contamination model that combines two kinds of corruptions: (i) small…

Data Structures and Algorithms · Computer Science 2024-10-23 Thanasis Pittas , Ankit Pensia

Multireference alignment (MRA) problem is to estimate an underlying signal from a large number of noisy circularly-shifted observations. The existing methods are always proposed under the hypothesis of a single Gaussian noise. However, the…

Optimization and Control · Mathematics 2021-07-23 Cuicui Zhao , Jun Liu , Xinqi Gong

Mixed-effects models have emerged as the gold standard of statistical analysis in different sub-fields of linguistics (Baayen, Davidson & Bates, 2008; Johnson, 2009; Barr, et al, 2013; Gries, 2015). One problematic feature of these models…

Applications · Statistics 2017-01-19 Christopher Eager , Joseph Roy

This paper studies a factor modeling-based approach for clustering high-dimensional data generated from a mixture of strongly correlated variables. Statistical modeling with correlated structures pervades modern applications in economics,…

Statistics Theory · Mathematics 2024-08-23 Shange Tang , Soham Jana , Jianqing Fan

The theory behind compressive sampling pre-supposes that a given sequence of observations may be exactly represented by a linear combination of a small number of basis vectors. In practice, however, even small deviations from an exact…

Optimization and Control · Mathematics 2014-06-30 Jonathan M. Nichols , Albert K. Oh , Rebecca M. Willett

We study the performance of the spectral method for the phase synchronization problem with additive Gaussian noises and incomplete data. The spectral method utilizes the leading eigenvector of the data matrix followed by a normalization…

Statistics Theory · Mathematics 2024-01-09 Anderson Ye Zhang

Consider the problem of estimating the $\gamma$-level set $G^*_{\gamma}=\{x:f(x)\geq\gamma\}$ of an unknown $d$-dimensional density function $f$ based on $n$ independent observations $X_1,...,X_n$ from the density. This problem has been…

Statistics Theory · Mathematics 2009-08-26 Aarti Singh , Clayton Scott , Robert Nowak

Genome-Scale Metabolic Models (GEMs) describe the interactions between genes, proteins, and the biochemical reactions that underpin an organism's metabolism aiming to computationally simulate functions at the cellular level. While many…

It is generally believed that ensemble approaches, which combine multiple algorithms or models, can outperform any single algorithm at machine learning tasks, such as prediction. In this paper, we propose Bayesian convex and linear…

Statistics Theory · Mathematics 2014-03-07 Yun Yang , David B. Dunson

Several researchers have experimentally shown that substantial improvements can be obtained in difficult pattern recognition problems by combining or integrating the outputs of multiple classifiers. This chapter provides an analytical…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Kagan Tumer , Joydeep Ghosh
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