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We consider a chemical reaction network governed by mass action kinetics and composed of N different species which can reversibly form heterodimers. A fast iterative algorithm is introduced to compute the equilibrium concentrations of such…

Molecular Networks · Quantitative Biology 2011-10-13 M. G. A. van Dorp , F. Berger , E. Carlon

Estimating the causal effects of interventions is crucial to policy and decision-making, yet outcome data are often missing or subject to non-standard measurement error. While ground-truth outcomes can sometimes be obtained through costly…

Machine Learning · Statistics 2026-04-22 Ezinne Nwankwo , Lauri Goldkind , Angela Zhou

Field experiments and computer simulations are effective but time-consuming methods of measuring the quality of engineered systems at different settings. To reduce the total time required, experimenters may employ Bayesian optimization,…

Machine Learning · Computer Science 2024-04-30 Jiuge Ren , David Sweet

Decentralized stochastic optimization has emerged as a fundamental paradigm for large-scale machine learning. However, practical implementations often rely on biased gradient estimators arising from communication compression or inexact…

Optimization and Control · Mathematics 2026-04-10 Qing Xu , Yiwei Liao , Wenqi Fan , Xingxing You , Songyi Dian

Multi-modal hashing methods have gained popularity due to their fast speed and low storage requirements. Among them, the supervised methods demonstrate better performance by utilizing labels as supervisory signals compared with unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2024-12-20 Jin-Yu Liu , Xian-Ling Mao , Tian-Yi Che , Rong-Cheng Tu

Many major works in social science employ matching to make causal conclusions, but different matches on the same data may produce different treatment effect estimates, even when they achieve similar balance or minimize the same loss…

Applications · Statistics 2023-03-23 Marco Morucci , Cynthia Rudin

Modeling complex physical systems such as they arise in civil engineering applications requires finding a trade-off between physical fidelity and practicality. Consequently, deviations of simulation from measurements are ubiquitous even…

Computational Engineering, Finance, and Science · Computer Science 2026-03-18 Paolo Villani , Daniel Andrés Arcones , Jörg F. Unger , Martin Weiser

Previous research on nonlinear oscillator networks has shown that chaos synchronization is attainable for identical oscillators but deteriorates in the presence of parameter mismatches. Here, we identify regimes for which the opposite…

Adaptation and Self-Organizing Systems · Physics 2021-04-29 Yoshiki Sugitani , Yuanzhao Zhang , Adilson E. Motter

The authors propose robust adaptive strategies based on stochastic minimax optimization for a series of simulated treatments on a one-dimensional patient phantom. The plan applied during the first fractions should be able to handle…

Optimization and Control · Mathematics 2018-10-01 Michelle Böck , Anders Forsgren , Kjell Eriksson , Björn Hårdemark

Mixture-of-Experts (MoE) models have shown remarkable capability in instruction tuning, especially when the number of tasks scales. However, previous methods simply merge all training tasks (e.g. creative writing, coding, and mathematics)…

Computation and Language · Computer Science 2024-06-18 Tong Zhu , Daize Dong , Xiaoye Qu , Jiacheng Ruan , Wenliang Chen , Yu Cheng

We study a new aggregation operator for gradients coming from a mini-batch for stochastic gradient (SG) methods that allows a significant speed-up in the case of sparse optimization problems. We call this method AdaBatch and it only…

Machine Learning · Computer Science 2017-11-07 Alexandre Défossez , Francis Bach

The emergence of Big Data has enabled new research perspectives in the discrete choice community. While the techniques to estimate Machine Learning models on a massive amount of data are well established, these have not yet been fully…

Optimization and Control · Mathematics 2020-12-23 Gael Lederrey , Virginie Lurkin , Tim Hillel , Michel Bierlaire

Analytical join queries over unstructured data are increasingly prevalent in data analytics. Applying machine learning (ML) models to label every pair in the cross product of tables can achieve state-of-the-art accuracy, but the cost of…

Databases · Computer Science 2026-03-18 Yuxuan Zhu , Tengjun Jin , Chenghao Mo , Daniel Kang

We develop fast distribution-free conformal prediction algorithms for obtaining multivalid coverage on exchangeable data in the batch setting. Multivalid coverage guarantees are stronger than marginal coverage guarantees in two ways: (1)…

Machine Learning · Computer Science 2022-10-03 Christopher Jung , Georgy Noarov , Ramya Ramalingam , Aaron Roth

Noisy matrix completion has attracted significant attention due to its applications in recommendation systems, signal processing and image restoration. Most existing works rely on (weighted) least squares methods under various low-rank…

Machine Learning · Statistics 2024-12-17 Ziyuan Chen , Fang Yao

In particle physics, as in many areas of science, parameter inference relies on simulations to bridge the gap between theory and experiment. Recent developments in simulation-based inference have boosted the sensitivity of analyses;…

High Energy Physics - Phenomenology · Physics 2026-04-23 Ezequiel Alvarez , Sean Benevedes , Manuel Szewc , Jesse Thaler

Imperfect molecular detection in single-cell experiments introduces technical noise that obscures the true stochastic dynamics of gene regulatory networks. While binomial models of molecular capture provide a principled description of…

Molecular Networks · Quantitative Biology 2025-12-03 Iryna Zabaikina , Ramon Grima

Clustering is a pivotal challenge in unsupervised machine learning and is often investigated through the lens of mixture models. The optimal error rate for recovering cluster labels in Gaussian and sub-Gaussian mixture models involves ad…

Statistics Theory · Mathematics 2024-07-18 Maximilien Dreveton , Alperen Gözeten , Matthias Grossglauser , Patrick Thiran

Clustering mixed data presents numerous challenges inherent to the very heterogeneous nature of the variables. A clustering algorithm should be able, despite of this heterogeneity, to extract discriminant pieces of information from the…

Machine Learning · Computer Science 2022-05-10 Robin Fuchs , Denys Pommeret , Cinzia Viroli

Recent advancements in Mixed Integer Optimization (MIO) algorithms, paired with hardware enhancements, have led to significant speedups in resolving MIO problems. These strategies have been utilized for optimal subset selection,…

Methodology · Statistics 2024-03-27 Madhav Sankaranarayanan , Intekhab Hossain , Tom Chen
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