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The large-scale development of large language models (LLMs) in medical contexts, such as diagnostic assistance and treatment recommendations, necessitates that these models possess accurate medical knowledge and deliver traceable…

Artificial Intelligence · Computer Science 2025-08-12 Qiyuan Li , Haijiang Liu , Caicai Guo , Chao Gao , Deyu Chen , Meng Wang , Feng Gao , Frank van Harmelen , Jinguang Gu

The use of machine learning (ML) techniques in the biomedical field has become increasingly important, particularly with the large amounts of data generated by the aftermath of the COVID-19 pandemic. However, due to the complex nature of…

Machine Learning · Computer Science 2023-03-17 Anthony Onoja , Francesco Raimondi

Healthcare requires AI that is predictive, reliable, and data-efficient. However, recent generative models lack physical foundation and temporal reasoning required for clinical decision support. As scaling language models show diminishing…

Machine Learning · Computer Science 2025-11-21 Mohammad Areeb Qazi , Maryam Nadeem , Mohammad Yaqub

Time series forecasting has applications across domains and industries, especially in healthcare, but the technical expertise required to analyze data, build models, and interpret results can be a barrier to using these techniques. This…

Machine Learning · Computer Science 2025-12-10 Aaron D. Mullen , Daniel R. Harris , Svetla Slavova , V. K. Cody Bumgardner

In biomedical research, unified access to up-to-date domain-specific knowledge is crucial, as such knowledge is continuously accumulated in scientific literature and structured resources. Identifying and extracting specific information is a…

Information Retrieval · Computer Science 2020-06-03 Anastasios Nentidis , Konstantinos Bougiatiotis , Anastasia Krithara , Georgios Paliouras

The recent boom of large language models (LLMs) has re-ignited the hope that artificial intelligence (AI) systems could aid medical diagnosis. Yet despite dazzling benchmark scores, LLM assistants have yet to deliver measurable improvements…

Artificial Intelligence · Computer Science 2025-07-03 Matthew JY Kang , Wenli Yang , Monica R Roberts , Byeong Ho Kang , Charles B Malpas

Medical education relies heavily on Simulated Patients (SPs) to provide a safe environment for students to practice clinical skills, including medical image analysis. However, the high cost of recruiting qualified SPs and the lack of…

Artificial Intelligence · Computer Science 2024-08-23 Yanzeng Li , Cheng Zeng , Jinchao Zhang , Jie Zhou , Lei Zou

Benefiting from the powerful expressive capability of graphs, graph-based approaches have been popularly applied to handle multi-modal medical data and achieved impressive performance in various biomedical applications. For disease…

Machine Learning · Computer Science 2022-03-14 Shuai Zheng , Zhenfeng Zhu , Zhizhe Liu , Zhenyu Guo , Yang Liu , Yuchen Yang , Yao Zhao

Citation recommendation for research papers is a valuable task that can help researchers improve the quality of their work by suggesting relevant related work. Current approaches for this task rely primarily on the text of the papers and…

Digital Libraries · Computer Science 2021-06-11 Arthur Brack , Anett Hoppe , Ralph Ewerth

In the field of medicine and healthcare, the utilization of medical expertise, based on medical knowledge combined with patients' health information is a life-critical challenge for patients and health professionals. The within-laying…

Artificial Intelligence · Computer Science 2025-10-13 Mubaris Nadeem , Madjid Fathi

Question answering (QA) systems are increasingly deployed across domains. However, their reliability is undermined when retrieved evidence is incomplete, noisy, or uncertain. Existing knowledge graph (KG) based QA frameworks typically…

Computation and Language · Computer Science 2026-01-16 Yu Takahashi , Shun Takeuchi , Kexuan Xin , Guillaume Pelat , Yoshiaki Ikai , Junya Saito , Jonathan Vitale , Shlomo Berkovsky , Amin Beheshti

Many clinical deep learning algorithms are population-based and difficult to interpret. Such properties limit their clinical utility as population-based findings may not generalize to individual patients and physicians are reluctant to…

Signal Processing · Electrical Eng. & Systems 2020-12-01 Dani Kiyasseh , Tingting Zhu , David A. Clifton

Personalized recommendations are popular in these days of Internet driven activities, specifically shopping. Recommendation methods can be grouped into three major categories, content based filtering, collaborative filtering and machine…

Information Retrieval · Computer Science 2021-01-11 Yuhao Mao , Serguei A. Mokhov , Sudhir P. Mudur

The dearth of prescribing guidelines for physicians is one key driver of the current opioid epidemic in the United States. In this work, we analyze medical and pharmaceutical claims data to draw insights on characteristics of patients who…

Machine Learning · Computer Science 2020-05-01 Chirag Nagpal , Dennis Wei , Bhanukiran Vinzamuri , Monica Shekhar , Sara E. Berger , Subhro Das , Kush R. Varshney

Exponential growth in Electronic Healthcare Records (EHR) has resulted in new opportunities and urgent needs for discovery of meaningful data-driven representations and patterns of diseases in Computational Phenotyping research. Deep…

Machine Learning · Statistics 2015-12-14 Zhengping Che , Sanjay Purushotham , Robinder Khemani , Yan Liu

With large volumes of health care data comes the research area of computational phenotyping, making use of techniques such as machine learning to describe illnesses and other clinical concepts from the data itself. The "traditional"…

Machine Learning · Statistics 2016-12-30 Chris Hodapp

Knowledge graphs (KGs) are the cornerstone of the semantic web, offering up-to-date representations of real-world entities and relations. Yet large language models (LLMs) remain largely static after pre-training, causing their internal…

Computation and Language · Computer Science 2026-03-24 Songlin Zhai , Guilin Qi , Yue Wang , Yuan Meng

Parkinson's Disease (PD) affects millions globally, impacting movement. Prior research utilized deep learning for PD prediction, primarily focusing on medical images, neglecting the data's underlying manifold structure. This work proposes a…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Jun-En Ding , Chien-Chin Hsu , Feng Liu

The `pre-train, prompt, predict' paradigm of large language models (LLMs) has achieved remarkable success in open-domain question answering (OD-QA). However, few works explore this paradigm in the scenario of multi-document question…

Computation and Language · Computer Science 2023-12-27 Yu Wang , Nedim Lipka , Ryan A. Rossi , Alexa Siu , Ruiyi Zhang , Tyler Derr

The integration of deep learning approaches in biomedical research has been transformative, enabling breakthroughs in various applications. Despite these strides, its application in protein inference is impeded by the scarcity of…

Machine Learning · Computer Science 2026-05-07 Zheng Ma , Jiazhen Chen , Lei Xin , Ali Ghodsi